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Note: You're navigating the results of models obtained with IntOGen (2020). A new boostDM version is available here.
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Mutation AA change Consequence type BoostDM score IntOGen frequency
2:29220829:T F1174L missense_variant 1.00 13
2:29209798:T R1275Q missense_variant 1.00 11
2:29220831:G F1174L missense_variant 1.00 2
2:29220831:C F1174V missense_variant 1.00 1
2:29220831:T F1174I missense_variant 1.00 1
2:29220830:C F1174C missense_variant 1.00 1
2:29209798:A R1275L missense_variant 1.00 1
2:29222350:G I1170T missense_variant 0.97 1
2:29213993:C F1245C missense_variant 0.97 1
2:29213994:T F1245I missense_variant 0.97 1
2:29213993:T F1245Y missense_variant 0.97 1
2:29222584:G G1128A missense_variant 0.94 1
2:29220765:T L1196M missense_variant 0.69 1
2:29220829:C F1174L missense_variant 1.00 0
2:29220830:T F1174Y missense_variant 1.00 0
2:29220830:G F1174S missense_variant 1.00 0
2:29209798:G R1275P missense_variant 1.00 0
2:29214006:G E1241Q missense_variant 1.00 0
2:29214006:T E1241K missense_variant 1.00 0
2:29214006:A E1241* stop_gained 1.00 0
2:29222348:C I1171V missense_variant 0.98 0
2:29222348:G I1171L missense_variant 0.98 0
2:29222348:A I1171F missense_variant 0.98 0
2:29222351:C I1170V missense_variant 0.98 0
2:29222351:A I1170F missense_variant 0.98 0
2:29222351:G I1170L missense_variant 0.98 0
2:29222347:G I1171T missense_variant 0.98 0
2:29222347:T I1171N missense_variant 0.98 0
2:29222347:C I1171S missense_variant 0.98 0
2:29220764:T L1196Q missense_variant 0.98 0
2:29220764:G L1196P missense_variant 0.98 0
2:29220764:C L1196R missense_variant 0.98 0
2:29222350:T I1170N missense_variant 0.97 0
2:29222350:C I1170S missense_variant 0.97 0
2:29214008:C L1240W missense_variant 0.97 0
2:29214008:G L1240S missense_variant 0.97 0
2:29213994:C F1245V missense_variant 0.97 0
2:29213994:G F1245L missense_variant 0.97 0
2:29213993:G F1245S missense_variant 0.97 0
2:29220747:G G1202R missense_variant 0.96 0
2:29220747:T G1202R missense_variant 0.96 0
2:29220746:T G1202E missense_variant 0.96 0
2:29220746:A G1202V missense_variant 0.96 0
2:29220746:G G1202A missense_variant 0.96 0
2:29197644:T S1324Y missense_variant 0.96 0
2:29197644:C S1324C missense_variant 0.96 0
2:29197644:A S1324F missense_variant 0.96 0
2:29222366:A L1165F missense_variant 0.96 0
2:29222366:C L1165V missense_variant 0.96 0
2:29222366:T L1165I missense_variant 0.96 0
2:29214075:A P1218S missense_variant 0.96 0
2:29214075:T P1218T missense_variant 0.96 0
2:29214075:C P1218A missense_variant 0.96 0
2:29220822:T Q1177K missense_variant 0.96 0
2:29220822:C Q1177E missense_variant 0.96 0
2:29207174:C T1312R missense_variant 0.96 0
2:29207174:T T1312K missense_variant 0.96 0
2:29207174:A T1312I missense_variant 0.96 0
2:29196804:A A1377V missense_variant 0.96 0
2:29220730:C F1207L missense_variant 0.96 0
2:29220759:A L1198F missense_variant 0.96 0
2:29220785:T S1189Y missense_variant 0.96 0
2:29220759:T L1198I missense_variant 0.96 0
2:29196804:T A1377D missense_variant 0.96 0
2:29220752:C A1200G missense_variant 0.96 0
2:29220752:A A1200V missense_variant 0.96 0
2:29220730:T F1207L missense_variant 0.96 0
2:29220752:T A1200E missense_variant 0.96 0
2:29220785:C S1189C missense_variant 0.96 0
2:29220785:A S1189F missense_variant 0.96 0
2:29220759:C L1198V missense_variant 0.96 0
2:29196804:C A1377G missense_variant 0.96 0
2:29214008:T L1240* stop_gained 0.96 0
2:29222537:T P1144T missense_variant 0.95 0
2:29222537:C P1144A missense_variant 0.95 0
2:29222537:A P1144S missense_variant 0.95 0
2:29220833:C K1173R missense_variant 0.95 0
2:29222345:G S1172R missense_variant 0.95 0
2:29222345:C S1172G missense_variant 0.95 0
2:29222345:A S1172C missense_variant 0.95 0
2:29220833:A K1173I missense_variant 0.95 0
2:29220834:G K1173Q missense_variant 0.95 0
2:29220834:C K1173E missense_variant 0.95 0
2:29220833:G K1173T missense_variant 0.95 0
2:29214032:A D1232V missense_variant 0.95 0
2:29214032:C D1232G missense_variant 0.95 0
2:29214032:G D1232A missense_variant 0.95 0
2:29197608:A Q1336L missense_variant 0.95 0
2:29197608:C Q1336R missense_variant 0.95 0
2:29197608:G Q1336P missense_variant 0.95 0
2:29196850:C M1362V missense_variant 0.95 0
2:29196850:G M1362L missense_variant 0.95 0
2:29197611:A N1335I missense_variant 0.95 0
2:29197611:C N1335S missense_variant 0.95 0
2:29197611:G N1335T missense_variant 0.95 0
2:29197612:A N1335Y missense_variant 0.95 0
2:29197612:C N1335D missense_variant 0.95 0
2:29197612:G N1335H missense_variant 0.95 0
2:29214053:A D1225V missense_variant 0.95 0
2:29214053:C D1225G missense_variant 0.95 0
2:29214053:G D1225A missense_variant 0.95 0
2:29197605:A E1337V missense_variant 0.95 0
2:29209820:G I1268L missense_variant 0.95 0
2:29209822:A K1267M missense_variant 0.95 0
2:29209822:C K1267R missense_variant 0.95 0
2:29209822:G K1267T missense_variant 0.95 0
2:29220819:A N1178Y missense_variant 0.95 0
2:29209823:C K1267E missense_variant 0.95 0
2:29209823:G K1267Q missense_variant 0.95 0
2:29196811:G N1375H missense_variant 0.95 0
2:29196792:A E1381V missense_variant 0.95 0
2:29196792:C E1381G missense_variant 0.95 0
2:29220818:G N1178T missense_variant 0.95 0
2:29220818:C N1178S missense_variant 0.95 0
2:29220818:A N1178I missense_variant 0.95 0
2:29220816:G I1179L missense_variant 0.95 0
2:29220816:C I1179V missense_variant 0.95 0
2:29220816:A I1179F missense_variant 0.95 0
2:29220810:T R1181S missense_variant 0.95 0
2:29220810:C R1181G missense_variant 0.95 0
2:29220810:A R1181C missense_variant 0.95 0
2:29209850:A T1258S missense_variant 0.95 0
2:29209850:C T1258A missense_variant 0.95 0
2:29209850:G T1258P missense_variant 0.95 0
2:29220795:G S1186R missense_variant 0.95 0
2:29220795:C S1186G missense_variant 0.95 0
2:29220795:A S1186C missense_variant 0.95 0
2:29209861:A N1254I missense_variant 0.95 0
2:29209861:C N1254S missense_variant 0.95 0
2:29209861:G N1254T missense_variant 0.95 0
2:29209862:A N1254Y missense_variant 0.95 0
2:29209862:C N1254D missense_variant 0.95 0
2:29209862:G N1254H missense_variant 0.95 0
2:29196792:G E1381A missense_variant 0.95 0
2:29196802:A I1378F missense_variant 0.95 0
2:29196847:A T1363S missense_variant 0.95 0
2:29220771:G I1194L missense_variant 0.95 0
2:29220771:C I1194V missense_variant 0.95 0
2:29220771:A I1194F missense_variant 0.95 0
2:29196847:C T1363A missense_variant 0.95 0
2:29196847:G T1363P missense_variant 0.95 0
2:29209874:A I1250F missense_variant 0.95 0
2:29209874:C I1250V missense_variant 0.95 0
2:29209874:G I1250L missense_variant 0.95 0
2:29209876:A D1249V missense_variant 0.95 0
2:29209876:C D1249G missense_variant 0.95 0
2:29209876:G D1249A missense_variant 0.95 0
2:29213987:A H1247L missense_variant 0.95 0
2:29213987:C H1247R missense_variant 0.95 0
2:29213987:G H1247P missense_variant 0.95 0
2:29197596:A E1340V missense_variant 0.95 0
2:29197596:C E1340G missense_variant 0.95 0
2:29197596:G E1340A missense_variant 0.95 0
2:29213991:A I1246F missense_variant 0.95 0
2:29213991:C I1246V missense_variant 0.95 0
2:29213991:G I1246L missense_variant 0.95 0
2:29213996:A H1244L missense_variant 0.95 0
2:29213996:C H1244R missense_variant 0.95 0
2:29213996:G H1244P missense_variant 0.95 0
2:29196802:C I1378V missense_variant 0.95 0
2:29213999:A N1243I missense_variant 0.95 0
2:29213999:C N1243S missense_variant 0.95 0
2:29213999:G N1243T missense_variant 0.95 0
2:29214000:A N1243Y missense_variant 0.95 0
2:29214000:C N1243D missense_variant 0.95 0
2:29214000:G N1243H missense_variant 0.95 0
2:29214002:A E1242V missense_variant 0.95 0
2:29214002:C E1242G missense_variant 0.95 0
2:29214002:G E1242A missense_variant 0.95 0
2:29214005:A E1241V missense_variant 0.95 0
2:29214005:C E1241G missense_variant 0.95 0
2:29214005:G E1241A missense_variant 0.95 0
2:29220761:G E1197A missense_variant 0.95 0
2:29220761:C E1197G missense_variant 0.95 0
2:29214011:A Y1239F missense_variant 0.95 0
2:29214011:C Y1239C missense_variant 0.95 0
2:29214011:G Y1239S missense_variant 0.95 0
2:29196802:G I1378L missense_variant 0.95 0
2:29196850:A M1362L missense_variant 0.95 0
2:29209820:C I1268V missense_variant 0.95 0
2:29197605:C E1337G missense_variant 0.95 0
2:29197605:G E1337A missense_variant 0.95 0
2:29214030:A I1233F missense_variant 0.95 0
2:29214030:C I1233V missense_variant 0.95 0
2:29214030:G I1233L missense_variant 0.95 0
2:29197615:A S1334C missense_variant 0.95 0
2:29197615:C S1334G missense_variant 0.95 0
2:29197615:G S1334R missense_variant 0.95 0
2:29214060:A M1223L missense_variant 0.95 0
2:29214060:C M1223V missense_variant 0.95 0
2:29214060:G M1223L missense_variant 0.95 0
2:29196819:A D1372V missense_variant 0.95 0
2:29220761:A E1197V missense_variant 0.95 0
2:29197626:A Y1330F missense_variant 0.95 0
2:29197626:C Y1330C missense_variant 0.95 0
2:29197626:G Y1330S missense_variant 0.95 0
2:29196858:A Y1359F missense_variant 0.95 0
2:29196858:C Y1359C missense_variant 0.95 0
2:29220722:A E1210V missense_variant 0.95 0
2:29220722:C E1210G missense_variant 0.95 0
2:29220722:G E1210A missense_variant 0.95 0
2:29220737:A K1205M missense_variant 0.95 0
2:29220737:C K1205R missense_variant 0.95 0
2:29220737:G K1205T missense_variant 0.95 0
2:29220756:G M1199L missense_variant 0.95 0
2:29220738:C K1205E missense_variant 0.95 0
2:29220738:G K1205Q missense_variant 0.95 0
2:29220743:A D1203V missense_variant 0.95 0
2:29220743:C D1203G missense_variant 0.95 0
2:29220743:G D1203A missense_variant 0.95 0
2:29220756:C M1199V missense_variant 0.95 0
2:29220756:A M1199L missense_variant 0.95 0
2:29196858:G Y1359S missense_variant 0.95 0
2:29196819:C D1372G missense_variant 0.95 0
2:29196819:G D1372A missense_variant 0.95 0
2:29196822:A E1371V missense_variant 0.95 0
2:29196822:C E1371G missense_variant 0.95 0
2:29196822:G E1371A missense_variant 0.95 0
2:29222596:G H1124P missense_variant 0.95 0
2:29196831:A H1368L missense_variant 0.95 0
2:29196831:C H1368R missense_variant 0.95 0
2:29196831:G H1368P missense_variant 0.95 0
2:29222596:C H1124R missense_variant 0.95 0
2:29222596:A H1124L missense_variant 0.95 0
2:29196834:A Q1367L missense_variant 0.95 0
2:29197651:A I1322F missense_variant 0.95 0
2:29197651:C I1322V missense_variant 0.95 0
2:29197651:G I1322L missense_variant 0.95 0
2:29197653:A E1321V missense_variant 0.95 0
2:29197653:C E1321G missense_variant 0.95 0
2:29197653:G E1321A missense_variant 0.95 0
2:29196834:C Q1367R missense_variant 0.95 0
2:29196834:G Q1367P missense_variant 0.95 0
2:29197560:A K1352M missense_variant 0.95 0
2:29197560:C K1352R missense_variant 0.95 0
2:29197560:G K1352T missense_variant 0.95 0
2:29196810:A N1375I missense_variant 0.95 0
2:29196810:C N1375S missense_variant 0.95 0
2:29196810:G N1375T missense_variant 0.95 0
2:29196811:A N1375Y missense_variant 0.95 0
2:29196811:C N1375D missense_variant 0.95 0
2:29207175:A T1312S missense_variant 0.95 0
2:29207175:C T1312A missense_variant 0.95 0
2:29207175:G T1312P missense_variant 0.95 0
2:29207177:A D1311V missense_variant 0.95 0
2:29207177:C D1311G missense_variant 0.95 0
2:29207177:G D1311A missense_variant 0.95 0
2:29222581:G E1129A missense_variant 0.95 0
2:29197569:A D1349V missense_variant 0.95 0
2:29197569:C D1349G missense_variant 0.95 0
2:29197569:G D1349A missense_variant 0.95 0
2:29207181:A T1310S missense_variant 0.95 0
2:29207181:C T1310A missense_variant 0.95 0
2:29207181:G T1310P missense_variant 0.95 0
2:29207183:A K1309I missense_variant 0.95 0
2:29207183:C K1309R missense_variant 0.95 0
2:29207183:G K1309T missense_variant 0.95 0
2:29222581:C E1129G missense_variant 0.95 0
2:29207184:C K1309E missense_variant 0.95 0
2:29207184:G K1309Q missense_variant 0.95 0
2:29222581:A E1129V missense_variant 0.95 0
2:29207190:A T1307S missense_variant 0.95 0
2:29207190:C T1307A missense_variant 0.95 0
2:29207190:G T1307P missense_variant 0.95 0
2:29222575:G Y1131S missense_variant 0.95 0
2:29222575:C Y1131C missense_variant 0.95 0
2:29222575:A Y1131F missense_variant 0.95 0
2:29222572:G E1132A missense_variant 0.95 0
2:29222572:C E1132G missense_variant 0.95 0
2:29222572:A E1132V missense_variant 0.95 0
2:29207201:A E1303V missense_variant 0.95 0
2:29207201:C E1303G missense_variant 0.95 0
2:29207201:G E1303A missense_variant 0.95 0
2:29196843:A Q1364L missense_variant 0.95 0
2:29207213:A E1299V missense_variant 0.95 0
2:29207213:C E1299G missense_variant 0.95 0
2:29207213:G E1299A missense_variant 0.95 0
2:29197573:A M1348L missense_variant 0.95 0
2:29197573:C M1348V missense_variant 0.95 0
2:29197573:G M1348L missense_variant 0.95 0
2:29207223:A M1296L missense_variant 0.95 0
2:29207223:C M1296V missense_variant 0.95 0
2:29207223:G M1296L missense_variant 0.95 0
2:29222408:G T1151P missense_variant 0.95 0
2:29222408:C T1151A missense_variant 0.95 0
2:29222408:A T1151S missense_variant 0.95 0
2:29222398:G E1154A missense_variant 0.95 0
2:29222398:C E1154G missense_variant 0.95 0
2:29222398:A E1154V missense_variant 0.95 0
2:29207228:A K1294M missense_variant 0.95 0
2:29207228:C K1294R missense_variant 0.95 0
2:29207228:G K1294T missense_variant 0.95 0
2:29207229:C K1294E missense_variant 0.95 0
2:29207229:G K1294Q missense_variant 0.95 0
2:29222386:G E1158A missense_variant 0.95 0
2:29222386:C E1158G missense_variant 0.95 0
2:29222386:A E1158V missense_variant 0.95 0
2:29222383:G Q1159P missense_variant 0.95 0
2:29222383:C Q1159R missense_variant 0.95 0
2:29207241:A M1290L missense_variant 0.95 0
2:29207241:C M1290V missense_variant 0.95 0
2:29207241:G M1290L missense_variant 0.95 0
2:29197585:A S1344C missense_variant 0.95 0
2:29197585:C S1344G missense_variant 0.95 0
2:29197585:G S1344R missense_variant 0.95 0
2:29222383:A Q1159L missense_variant 0.95 0
2:29222380:G D1160A missense_variant 0.95 0
2:29222380:C D1160G missense_variant 0.95 0
2:29222380:A D1160V missense_variant 0.95 0
2:29222377:G E1161A missense_variant 0.95 0
2:29222377:C E1161G missense_variant 0.95 0
2:29222377:A E1161V missense_variant 0.95 0
2:29222371:G D1163A missense_variant 0.95 0
2:29222371:C D1163G missense_variant 0.95 0
2:29222371:A D1163V missense_variant 0.95 0
2:29207255:A K1285M missense_variant 0.95 0
2:29207255:C K1285R missense_variant 0.95 0
2:29207255:G K1285T missense_variant 0.95 0
2:29207256:C K1285E missense_variant 0.95 0
2:29207256:G K1285Q missense_variant 0.95 0
2:29207261:A Y1283F missense_variant 0.95 0
2:29207261:C Y1283C missense_variant 0.95 0
2:29207261:G Y1283S missense_variant 0.95 0
2:29207264:A Y1282F missense_variant 0.95 0
2:29207264:C Y1282C missense_variant 0.95 0
2:29207264:G Y1282S missense_variant 0.95 0
2:29222363:G M1166L missense_variant 0.95 0
2:29222363:C M1166V missense_variant 0.95 0
2:29222363:A M1166L missense_variant 0.95 0
2:29207268:A S1281C missense_variant 0.95 0
2:29207268:C S1281G missense_variant 0.95 0
2:29207268:G S1281R missense_variant 0.95 0
2:29196843:C Q1364R missense_variant 0.95 0
2:29196843:G Q1364P missense_variant 0.95 0
2:29222359:G E1167A missense_variant 0.95 0
2:29222359:C E1167G missense_variant 0.95 0
2:29222359:A E1167V missense_variant 0.95 0
2:29209789:A Y1278F missense_variant 0.95 0
2:29209789:C Y1278C missense_variant 0.95 0
2:29209789:G Y1278S missense_variant 0.95 0
2:29209793:A I1277F missense_variant 0.95 0
2:29209793:C I1277V missense_variant 0.95 0
2:29209793:G I1277L missense_variant 0.95 0
2:29209795:A D1276V missense_variant 0.95 0
2:29209795:C D1276G missense_variant 0.95 0
2:29209795:G D1276A missense_variant 0.95 0
2:29197588:A T1343S missense_variant 0.95 0
2:29197588:C T1343A missense_variant 0.95 0
2:29197588:G T1343P missense_variant 0.95 0
2:29209805:A M1273L missense_variant 0.95 0
2:29209805:C M1273V missense_variant 0.95 0
2:29209805:G M1273L missense_variant 0.95 0
2:29220828:G N1175H missense_variant 0.95 0
2:29220828:C N1175D missense_variant 0.95 0
2:29209813:A D1270V missense_variant 0.95 0
2:29209813:C D1270G missense_variant 0.95 0
2:29209813:G D1270A missense_variant 0.95 0
2:29220828:A N1175Y missense_variant 0.95 0
2:29220824:G H1176P missense_variant 0.95 0
2:29220824:C H1176R missense_variant 0.95 0
2:29220824:A H1176L missense_variant 0.95 0
2:29220821:G Q1177P missense_variant 0.95 0
2:29220821:C Q1177R missense_variant 0.95 0
2:29220821:A Q1177L missense_variant 0.95 0
2:29220819:G N1178H missense_variant 0.95 0
2:29220819:C N1178D missense_variant 0.95 0
2:29209820:A I1268F missense_variant 0.95 0
2:29220747:A G1202* stop_gained 0.94 0
2:29196789:G R1382T missense_variant 0.94 0
2:29197571:A M1348I missense_variant 0.94 0
2:29222579:A V1130L missense_variant 0.94 0
2:29222594:T G1125S missense_variant 0.94 0
2:29196789:T R1382K missense_variant 0.94 0
2:29222606:T G1121S missense_variant 0.94 0
2:29222570:T G1133S missense_variant 0.94 0
2:29222570:G G1133R missense_variant 0.94 0
2:29222570:A G1133C missense_variant 0.94 0
2:29197620:A S1332I missense_variant 0.94 0
2:29197581:A G1345V missense_variant 0.94 0
2:29197581:G G1345A missense_variant 0.94 0
2:29197581:T G1345E missense_variant 0.94 0
2:29222594:G G1125R missense_variant 0.94 0
2:29197654:G E1321Q missense_variant 0.94 0
2:29197654:T E1321K missense_variant 0.94 0
2:29197655:A W1320C missense_variant 0.94 0
2:29197655:G W1320C missense_variant 0.94 0
2:29222594:A G1125C missense_variant 0.94 0
2:29197656:A W1320L missense_variant 0.94 0
2:29197656:G W1320S missense_variant 0.94 0
2:29222593:T G1125D missense_variant 0.94 0
2:29197554:A C1354F missense_variant 0.94 0
2:29197554:G C1354S missense_variant 0.94 0
2:29197554:T C1354Y missense_variant 0.94 0
2:29222600:A G1123C missense_variant 0.94 0
2:29197582:G G1345R missense_variant 0.94 0
2:29222606:G G1121R missense_variant 0.94 0
2:29197582:T G1345R missense_variant 0.94 0
2:29197620:G S1332T missense_variant 0.94 0
2:29197620:T S1332N missense_variant 0.94 0
2:29222593:G G1125A missense_variant 0.94 0
2:29222593:A G1125V missense_variant 0.94 0
2:29222591:T A1126T missense_variant 0.94 0
2:29197668:A G1316V missense_variant 0.94 0
2:29197668:G G1316A missense_variant 0.94 0
2:29197668:T G1316E missense_variant 0.94 0
2:29222591:G A1126P missense_variant 0.94 0
2:29197669:G G1316R missense_variant 0.94 0
2:29197669:T G1316R missense_variant 0.94 0
2:29196816:G R1373T missense_variant 0.94 0
2:29196816:T R1373K missense_variant 0.94 0
2:29196836:A W1366C missense_variant 0.94 0
2:29196836:G W1366C missense_variant 0.94 0
2:29222606:A G1121C missense_variant 0.94 0
2:29196837:A W1366L missense_variant 0.94 0
2:29196837:G W1366S missense_variant 0.94 0
2:29222600:T G1123S missense_variant 0.94 0
2:29222569:T G1133D missense_variant 0.94 0
2:29197591:T V1342I missense_variant 0.94 0
2:29222600:G G1123R missense_variant 0.94 0
2:29196840:A C1365F missense_variant 0.94 0
2:29197676:A W1313C missense_variant 0.94 0
2:29197676:G W1313C missense_variant 0.94 0
2:29222591:A A1126S missense_variant 0.94 0
2:29222585:T G1128R missense_variant 0.94 0
2:29222585:G G1128R missense_variant 0.94 0
2:29222585:A G1128W missense_variant 0.94 0
2:29222584:T G1128E missense_variant 0.94 0
2:29197603:A V1338F missense_variant 0.94 0
2:29222584:A G1128V missense_variant 0.94 0
2:29196816:A R1373M missense_variant 0.94 0
2:29214058:A M1223I missense_variant 0.94 0
2:29214054:T D1225N missense_variant 0.94 0
2:29214054:G D1225H missense_variant 0.94 0
2:29197575:A R1347L missense_variant 0.94 0
2:29196855:A R1360L missense_variant 0.94 0
2:29196855:G R1360P missense_variant 0.94 0
2:29196855:T R1360Q missense_variant 0.94 0
2:29197575:G R1347P missense_variant 0.94 0
2:29197575:T R1347Q missense_variant 0.94 0
2:29197578:A G1346V missense_variant 0.94 0
2:29197578:G G1346A missense_variant 0.94 0
2:29197578:T G1346D missense_variant 0.94 0
2:29197579:A G1346C missense_variant 0.94 0
2:29197579:G G1346R missense_variant 0.94 0
2:29197579:T G1346S missense_variant 0.94 0
2:29214054:A D1225Y missense_variant 0.94 0
2:29222599:A G1123V missense_variant 0.94 0
2:29214033:T D1232N missense_variant 0.94 0
2:29222569:G G1133A missense_variant 0.94 0
2:29222569:A G1133V missense_variant 0.94 0
2:29197571:G M1348I missense_variant 0.94 0
2:29214033:G D1232H missense_variant 0.94 0
2:29214033:A D1232Y missense_variant 0.94 0
2:29197571:T M1348I missense_variant 0.94 0
2:29222579:T V1130M missense_variant 0.94 0
2:29222564:T V1135M missense_variant 0.94 0
2:29222564:G V1135L missense_variant 0.94 0
2:29222564:A V1135L missense_variant 0.94 0
2:29222546:T D1141N missense_variant 0.94 0
2:29222582:T E1129K missense_variant 0.94 0
2:29197591:A V1342F missense_variant 0.94 0
2:29197591:G V1342L missense_variant 0.94 0
2:29222546:G D1141H missense_variant 0.94 0
2:29222546:A D1141Y missense_variant 0.94 0
2:29196848:T M1362I missense_variant 0.94 0
2:29196848:G M1362I missense_variant 0.94 0
2:29197597:T E1340K missense_variant 0.94 0
2:29222573:T E1132K missense_variant 0.94 0
2:29214003:G E1242Q missense_variant 0.94 0
2:29214003:T E1242K missense_variant 0.94 0
2:29222573:G E1132Q missense_variant 0.94 0
2:29197606:T E1337K missense_variant 0.94 0
2:29197606:G E1337Q missense_variant 0.94 0
2:29222599:G G1123A missense_variant 0.94 0
2:29214027:T A1234T missense_variant 0.94 0
2:29214027:G A1234P missense_variant 0.94 0
2:29222579:G V1130L missense_variant 0.94 0
2:29196840:G C1365S missense_variant 0.94 0
2:29214027:A A1234S missense_variant 0.94 0
2:29214021:T G1236S missense_variant 0.94 0
2:29214021:G G1236R missense_variant 0.94 0
2:29196840:T C1365Y missense_variant 0.94 0
2:29197597:G E1340Q missense_variant 0.94 0
2:29213984:A R1248L missense_variant 0.94 0
2:29213984:G R1248P missense_variant 0.94 0
2:29222582:G E1129Q missense_variant 0.94 0
2:29222599:T G1123D missense_variant 0.94 0
2:29214021:A G1236C missense_variant 0.94 0
2:29197631:A M1328I missense_variant 0.94 0
2:29197631:G M1328I missense_variant 0.94 0
2:29197631:T M1328I missense_variant 0.94 0
2:29197543:A V1358L missense_variant 0.94 0
2:29197543:G V1358L missense_variant 0.94 0
2:29197543:T V1358I missense_variant 0.94 0
2:29214020:T G1236D missense_variant 0.94 0
2:29214020:G G1236A missense_variant 0.94 0
2:29196789:A R1382M missense_variant 0.94 0
2:29197638:A G1326V missense_variant 0.94 0
2:29197638:G G1326A missense_variant 0.94 0
2:29197638:T G1326E missense_variant 0.94 0
2:29213984:T R1248Q missense_variant 0.94 0
2:29197639:G G1326R missense_variant 0.94 0
2:29197639:T G1326R missense_variant 0.94 0
2:29196793:G E1381Q missense_variant 0.94 0
2:29196793:T E1381K missense_variant 0.94 0
2:29214058:G M1223I missense_variant 0.94 0
2:29214020:A G1236V missense_variant 0.94 0
2:29197603:T V1338I missense_variant 0.94 0
2:29197603:G V1338L missense_variant 0.94 0
2:29197549:A G1356W missense_variant 0.94 0
2:29197549:G G1356R missense_variant 0.94 0
2:29197549:T G1356R missense_variant 0.94 0
2:29196848:A M1362I missense_variant 0.94 0
2:29214058:T M1223I missense_variant 0.94 0
2:29220812:G V1180A missense_variant 0.94 0
2:29220803:G I1183T missense_variant 0.94 0
2:29220803:T I1183N missense_variant 0.94 0
2:29220807:C C1182G missense_variant 0.94 0
2:29222369:T F1164I missense_variant 0.94 0
2:29222369:G F1164L missense_variant 0.94 0
2:29222369:C F1164V missense_variant 0.94 0
2:29222368:T F1164Y missense_variant 0.94 0
2:29222368:G F1164S missense_variant 0.94 0
2:29220807:G C1182R missense_variant 0.94 0
2:29220807:T C1182S missense_variant 0.94 0
2:29220812:C V1180G missense_variant 0.94 0
2:29222368:C F1164C missense_variant 0.94 0
2:29220770:G I1194T missense_variant 0.94 0
2:29220770:T I1194N missense_variant 0.94 0
2:29222533:T L1145Q missense_variant 0.94 0
2:29222533:G L1145P missense_variant 0.94 0
2:29222533:C L1145R missense_variant 0.94 0
2:29222527:T V1147E missense_variant 0.94 0
2:29222527:G V1147A missense_variant 0.94 0
2:29222527:C V1147G missense_variant 0.94 0
2:29220773:C F1193C missense_variant 0.94 0
2:29220773:G F1193S missense_variant 0.94 0
2:29222365:T L1165H missense_variant 0.94 0
2:29220758:T L1198H missense_variant 0.94 0
2:29220758:G L1198P missense_variant 0.94 0
2:29220758:C L1198R missense_variant 0.94 0
2:29220732:C F1207V missense_variant 0.94 0
2:29220732:G F1207L missense_variant 0.94 0
2:29220732:T F1207I missense_variant 0.94 0
2:29222521:T V1149E missense_variant 0.94 0
2:29222521:G V1149A missense_variant 0.94 0
2:29222521:C V1149G missense_variant 0.94 0
2:29220740:C L1204R missense_variant 0.94 0
2:29220740:G L1204P missense_variant 0.94 0
2:29220740:T L1204H missense_variant 0.94 0
2:29222365:G L1165P missense_variant 0.94 0
2:29222365:C L1165R missense_variant 0.94 0
2:29220773:T F1193Y missense_variant 0.94 0
2:29220755:T M1199K missense_variant 0.94 0
2:29220755:G M1199T missense_variant 0.94 0
2:29220755:C M1199R missense_variant 0.94 0
2:29222374:C L1162R missense_variant 0.94 0
2:29220812:T V1180D missense_variant 0.94 0
2:29220815:C I1179S missense_variant 0.94 0
2:29220791:C L1187R missense_variant 0.94 0
2:29220791:G L1187P missense_variant 0.94 0
2:29222362:T M1166K missense_variant 0.94 0
2:29222395:T V1155E missense_variant 0.94 0
2:29222362:G M1166T missense_variant 0.94 0
2:29222362:C M1166R missense_variant 0.94 0
2:29220791:T L1187Q missense_variant 0.94 0
2:29222395:G V1155A missense_variant 0.94 0
2:29220797:C V1185G missense_variant 0.94 0
2:29220797:G V1185A missense_variant 0.94 0
2:29222395:C V1155G missense_variant 0.94 0
2:29222393:T C1156S missense_variant 0.94 0
2:29222393:G C1156R missense_variant 0.94 0
2:29222393:C C1156G missense_variant 0.94 0
2:29222390:T S1157T missense_variant 0.94 0
2:29222390:G S1157P missense_variant 0.94 0
2:29222390:C S1157A missense_variant 0.94 0
2:29220797:T V1185E missense_variant 0.94 0
2:29222353:C L1169R missense_variant 0.94 0
2:29220815:T I1179N missense_variant 0.94 0
2:29220803:C I1183S missense_variant 0.94 0
2:29220767:C L1195R missense_variant 0.94 0
2:29220767:G L1195P missense_variant 0.94 0
2:29220767:T L1195Q missense_variant 0.94 0
2:29220770:C I1194S missense_variant 0.94 0
2:29222374:T L1162Q missense_variant 0.94 0
2:29222374:G L1162P missense_variant 0.94 0
2:29220815:G I1179T missense_variant 0.94 0
2:29222353:T L1169Q missense_variant 0.94 0
2:29222353:G L1169P missense_variant 0.94 0
2:29222519:G K1150Q missense_variant 0.94 0
2:29222518:C K1150R missense_variant 0.94 0
2:29222518:G K1150T missense_variant 0.94 0
2:29222519:C K1150E missense_variant 0.94 0
2:29222530:A Q1146L missense_variant 0.94 0
2:29222530:C Q1146R missense_variant 0.94 0
2:29222518:A K1150M missense_variant 0.94 0
2:29222530:G Q1146P missense_variant 0.94 0
2:29220822:A Q1177* stop_gained 0.94 0
2:29223349:T L1118I missense_variant 0.94 0
2:29196795:C L1380W missense_variant 0.94 0
2:29196795:G L1380S missense_variant 0.94 0
2:29196798:C I1379S missense_variant 0.94 0
2:29196798:G I1379T missense_variant 0.94 0
2:29196798:T I1379N missense_variant 0.94 0
2:29196807:C F1376C missense_variant 0.94 0
2:29196807:G F1376S missense_variant 0.94 0
2:29196807:T F1376Y missense_variant 0.94 0
2:29196808:C F1376V missense_variant 0.94 0
2:29196808:G F1376L missense_variant 0.94 0
2:29196808:T F1376I missense_variant 0.94 0
2:29196813:A P1374L missense_variant 0.94 0
2:29196813:C P1374R missense_variant 0.94 0
2:29196813:T P1374H missense_variant 0.94 0
2:29196814:A P1374S missense_variant 0.94 0
2:29196814:C P1374A missense_variant 0.94 0
2:29196814:T P1374T missense_variant 0.94 0
2:29196825:A P1370L missense_variant 0.94 0
2:29196825:C P1370R missense_variant 0.94 0
2:29196825:T P1370H missense_variant 0.94 0
2:29196826:A P1370S missense_variant 0.94 0
2:29196826:C P1370A missense_variant 0.94 0
2:29196826:T P1370T missense_variant 0.94 0
2:29196832:A H1368Y missense_variant 0.94 0
2:29196832:C H1368D missense_variant 0.94 0
2:29196832:T H1368N missense_variant 0.94 0
2:29196835:C Q1367E missense_variant 0.94 0
2:29196835:T Q1367K missense_variant 0.94 0
2:29196838:C W1366G missense_variant 0.94 0
2:29196838:G W1366R missense_variant 0.94 0
2:29196838:T W1366R missense_variant 0.94 0
2:29196844:C Q1364E missense_variant 0.94 0
2:29196844:T Q1364K missense_variant 0.94 0
2:29196846:A T1363I missense_variant 0.94 0
2:29196846:C T1363S missense_variant 0.94 0
2:29196846:T T1363N missense_variant 0.94 0
2:29196849:C M1362R missense_variant 0.94 0
2:29196849:G M1362T missense_variant 0.94 0
2:29196849:T M1362K missense_variant 0.94 0
2:29196852:C I1361R missense_variant 0.94 0
2:29196852:G I1361T missense_variant 0.94 0
2:29196852:T I1361K missense_variant 0.94 0
2:29196859:C Y1359D missense_variant 0.94 0
2:29196859:G Y1359H missense_variant 0.94 0
2:29196859:T Y1359N missense_variant 0.94 0
2:29197542:C V1358G missense_variant 0.94 0
2:29197542:G V1358A missense_variant 0.94 0
2:29197542:T V1358E missense_variant 0.94 0
2:29197545:A P1357L missense_variant 0.94 0
2:29197545:C P1357R missense_variant 0.94 0
2:29197545:T P1357H missense_variant 0.94 0
2:29197546:A P1357S missense_variant 0.94 0
2:29197546:C P1357A missense_variant 0.94 0
2:29197546:T P1357T missense_variant 0.94 0
2:29197551:A P1355L missense_variant 0.94 0
2:29197551:C P1355R missense_variant 0.94 0
2:29197551:T P1355H missense_variant 0.94 0
2:29197552:A P1355S missense_variant 0.94 0
2:29197552:C P1355A missense_variant 0.94 0
2:29197552:T P1355T missense_variant 0.94 0
2:29197555:C C1354G missense_variant 0.94 0
2:29197555:G C1354R missense_variant 0.94 0
2:29197555:T C1354S missense_variant 0.94 0
2:29197563:A P1351L missense_variant 0.94 0
2:29197563:C P1351R missense_variant 0.94 0
2:29197563:T P1351H missense_variant 0.94 0
2:29197564:A P1351S missense_variant 0.94 0
2:29197564:C P1351A missense_variant 0.94 0
2:29197564:T P1351T missense_variant 0.94 0
2:29197566:A P1350L missense_variant 0.94 0
2:29197566:C P1350R missense_variant 0.94 0
2:29197566:T P1350Q missense_variant 0.94 0
2:29197567:A P1350S missense_variant 0.94 0
2:29197567:C P1350A missense_variant 0.94 0
2:29197567:T P1350T missense_variant 0.94 0
2:29197572:C M1348R missense_variant 0.94 0
2:29197572:G M1348T missense_variant 0.94 0
2:29197572:T M1348K missense_variant 0.94 0
2:29197587:A T1343I missense_variant 0.94 0
2:29197587:C T1343S missense_variant 0.94 0
2:29197587:T T1343N missense_variant 0.94 0
2:29197590:C V1342G missense_variant 0.94 0
2:29197590:G V1342A missense_variant 0.94 0
2:29197590:T V1342D missense_variant 0.94 0
2:29197593:C F1341C missense_variant 0.94 0
2:29197593:G F1341S missense_variant 0.94 0
2:29197593:T F1341Y missense_variant 0.94 0
2:29197594:C F1341V missense_variant 0.94 0
2:29197594:G F1341L missense_variant 0.94 0
2:29197594:T F1341I missense_variant 0.94 0
2:29197599:C L1339R missense_variant 0.94 0
2:29197599:G L1339P missense_variant 0.94 0
2:29197599:T L1339Q missense_variant 0.94 0
2:29197602:C V1338G missense_variant 0.94 0
2:29197602:G V1338A missense_variant 0.94 0
2:29197602:T V1338D missense_variant 0.94 0
2:29197609:C Q1336E missense_variant 0.94 0
2:29197609:T Q1336K missense_variant 0.94 0
2:29197623:A P1331L missense_variant 0.94 0
2:29197623:C P1331R missense_variant 0.94 0
2:29197623:T P1331H missense_variant 0.94 0
2:29197624:A P1331S missense_variant 0.94 0
2:29197624:C P1331A missense_variant 0.94 0
2:29197624:T P1331T missense_variant 0.94 0
2:29197627:C Y1330D missense_variant 0.94 0
2:29197627:G Y1330H missense_variant 0.94 0
2:29197627:T Y1330N missense_variant 0.94 0
2:29197629:A P1329L missense_variant 0.94 0
2:29197629:C P1329R missense_variant 0.94 0
2:29197629:T P1329Q missense_variant 0.94 0
2:29197630:A P1329S missense_variant 0.94 0
2:29197630:C P1329A missense_variant 0.94 0
2:29197630:T P1329T missense_variant 0.94 0
2:29197632:C M1328R missense_variant 0.94 0
2:29197632:G M1328T missense_variant 0.94 0
2:29197632:T M1328K missense_variant 0.94 0
2:29197636:C Y1327D missense_variant 0.94 0
2:29197636:G Y1327H missense_variant 0.94 0
2:29197636:T Y1327N missense_variant 0.94 0
2:29197641:C L1325R missense_variant 0.94 0
2:29197641:G L1325P missense_variant 0.94 0
2:29197641:T L1325H missense_variant 0.94 0
2:29197645:C S1324A missense_variant 0.94 0
2:29197645:G S1324P missense_variant 0.94 0
2:29197645:T S1324T missense_variant 0.94 0
2:29197647:C F1323C missense_variant 0.94 0
2:29197647:G F1323S missense_variant 0.94 0
2:29197647:T F1323Y missense_variant 0.94 0
2:29197650:C I1322S missense_variant 0.94 0
2:29197650:G I1322T missense_variant 0.94 0
2:29197650:T I1322N missense_variant 0.94 0
2:29197657:C W1320G missense_variant 0.94 0
2:29197657:G W1320R missense_variant 0.94 0
2:29197657:T W1320R missense_variant 0.94 0
2:29197659:C L1319R missense_variant 0.94 0
2:29197659:G L1319P missense_variant 0.94 0
2:29197659:T L1319Q missense_variant 0.94 0
2:29197662:C L1318R missense_variant 0.94 0
2:29197662:G L1318P missense_variant 0.94 0
2:29197662:T L1318Q missense_variant 0.94 0
2:29197671:C F1315C missense_variant 0.94 0
2:29197671:G F1315S missense_variant 0.94 0
2:29197671:T F1315Y missense_variant 0.94 0
2:29197672:C F1315V missense_variant 0.94 0
2:29197672:G F1315L missense_variant 0.94 0
2:29197672:T F1315I missense_variant 0.94 0
2:29197674:A S1314F missense_variant 0.94 0
2:29197674:C S1314C missense_variant 0.94 0
2:29197674:T S1314Y missense_variant 0.94 0
2:29197675:C S1314A missense_variant 0.94 0
2:29197675:G S1314P missense_variant 0.94 0
2:29197675:T S1314T missense_variant 0.94 0
2:29207180:A T1310I missense_variant 0.94 0
2:29207180:C T1310R missense_variant 0.94 0
2:29207180:T T1310K missense_variant 0.94 0
2:29207189:A T1307I missense_variant 0.94 0
2:29207189:C T1307S missense_variant 0.94 0
2:29207189:T T1307N missense_variant 0.94 0
2:29207210:A A1300V missense_variant 0.94 0
2:29207210:C A1300G missense_variant 0.94 0
2:29207210:T A1300D missense_variant 0.94 0
2:29207216:A P1298L missense_variant 0.94 0
2:29207216:C P1298R missense_variant 0.94 0
2:29207216:T P1298Q missense_variant 0.94 0
2:29207217:A P1298S missense_variant 0.94 0
2:29207217:C P1298A missense_variant 0.94 0
2:29207217:T P1298T missense_variant 0.94 0
2:29207219:A P1297L missense_variant 0.94 0
2:29207219:C P1297R missense_variant 0.94 0
2:29207219:T P1297H missense_variant 0.94 0
2:29207220:A P1297S missense_variant 0.94 0
2:29207220:C P1297A missense_variant 0.94 0
2:29207220:T P1297T missense_variant 0.94 0
2:29207234:A P1292L missense_variant 0.94 0
2:29207234:C P1292R missense_variant 0.94 0
2:29207234:T P1292Q missense_variant 0.94 0
2:29207235:A P1292S missense_variant 0.94 0
2:29207235:C P1292A missense_variant 0.94 0
2:29207235:T P1292T missense_variant 0.94 0
2:29207243:A A1289V missense_variant 0.94 0
2:29207243:C A1289G missense_variant 0.94 0
2:29207243:T A1289D missense_variant 0.94 0
2:29207270:A A1280V missense_variant 0.94 0
2:29207270:C A1280G missense_variant 0.94 0
2:29207270:T A1280E missense_variant 0.94 0
2:29209801:A A1274V missense_variant 0.94 0
2:29209801:C A1274G missense_variant 0.94 0
2:29209801:T A1274D missense_variant 0.94 0
2:29209825:A A1266V missense_variant 0.94 0
2:29209825:C A1266G missense_variant 0.94 0
2:29209825:T A1266D missense_variant 0.94 0
2:29209849:A T1258I missense_variant 0.94 0
2:29209849:C T1258S missense_variant 0.94 0
2:29209849:T T1258N missense_variant 0.94 0
2:29209867:A A1252V missense_variant 0.94 0
2:29209867:C A1252G missense_variant 0.94 0
2:29209867:T A1252D missense_variant 0.94 0
2:29209870:A A1251V missense_variant 0.94 0
2:29209870:C A1251G missense_variant 0.94 0
2:29209870:T A1251D missense_variant 0.94 0
2:29213988:A H1247Y missense_variant 0.94 0
2:29213988:C H1247D missense_variant 0.94 0
2:29213988:T H1247N missense_variant 0.94 0
2:29213990:C I1246S missense_variant 0.94 0
2:29213990:G I1246T missense_variant 0.94 0
2:29213990:T I1246N missense_variant 0.94 0
2:29213997:A H1244Y missense_variant 0.94 0
2:29213997:C H1244D missense_variant 0.94 0
2:29213997:T H1244N missense_variant 0.94 0
2:29214012:C Y1239D missense_variant 0.94 0
2:29214012:G Y1239H missense_variant 0.94 0
2:29214012:T Y1239N missense_variant 0.94 0
2:29214018:C C1237G missense_variant 0.94 0
2:29214018:G C1237R missense_variant 0.94 0
2:29214018:T C1237S missense_variant 0.94 0
2:29214026:A A1234V missense_variant 0.94 0
2:29214026:C A1234G missense_variant 0.94 0
2:29214026:T A1234D missense_variant 0.94 0
2:29214029:C I1233S missense_variant 0.94 0
2:29214029:G I1233T missense_variant 0.94 0
2:29214029:T I1233N missense_variant 0.94 0
2:29214038:A A1230V missense_variant 0.94 0
2:29214038:C A1230G missense_variant 0.94 0
2:29214038:T A1230D missense_variant 0.94 0
2:29214041:C V1229G missense_variant 0.94 0
2:29214041:G V1229A missense_variant 0.94 0
2:29214041:T V1229E missense_variant 0.94 0
2:29214047:C L1227R missense_variant 0.94 0
2:29214047:G L1227P missense_variant 0.94 0
2:29214047:T L1227Q missense_variant 0.94 0
2:29214050:C L1226R missense_variant 0.94 0
2:29214050:G L1226P missense_variant 0.94 0
2:29214050:T L1226H missense_variant 0.94 0
2:29214059:C M1223R missense_variant 0.94 0
2:29214059:G M1223T missense_variant 0.94 0
2:29214059:T M1223K missense_variant 0.94 0
2:29214065:C L1221R missense_variant 0.94 0
2:29214065:G L1221P missense_variant 0.94 0
2:29214065:T L1221Q missense_variant 0.94 0
2:29214071:A S1219F missense_variant 0.94 0
2:29214071:C S1219C missense_variant 0.94 0
2:29214071:T S1219Y missense_variant 0.94 0
2:29214078:C Q1217E missense_variant 0.94 0
2:29214078:T Q1217K missense_variant 0.94 0
2:29220713:A P1213L missense_variant 0.94 0
2:29220713:C P1213R missense_variant 0.94 0
2:29220713:T P1213H missense_variant 0.94 0
2:29220714:A P1213S missense_variant 0.94 0
2:29220714:C P1213A missense_variant 0.94 0
2:29220714:T P1213T missense_variant 0.94 0
2:29220779:A P1191L missense_variant 0.94 0
2:29220779:C P1191R missense_variant 0.94 0
2:29220779:T P1191H missense_variant 0.94 0
2:29220780:A P1191S missense_variant 0.94 0
2:29220780:C P1191A missense_variant 0.94 0
2:29220780:T P1191T missense_variant 0.94 0
2:29220825:A H1176Y missense_variant 0.94 0
2:29220825:C H1176D missense_variant 0.94 0
2:29220825:T H1176N missense_variant 0.94 0
2:29222356:A A1168V missense_variant 0.94 0
2:29222356:C A1168G missense_variant 0.94 0
2:29222356:T A1168D missense_variant 0.94 0
2:29222384:C Q1159E missense_variant 0.94 0
2:29222384:T Q1159K missense_variant 0.94 0
2:29222389:A S1157F missense_variant 0.94 0
2:29222389:C S1157C missense_variant 0.94 0
2:29222389:T S1157Y missense_variant 0.94 0
2:29222401:A P1153L missense_variant 0.94 0
2:29222401:C P1153R missense_variant 0.94 0
2:29222401:T P1153H missense_variant 0.94 0
2:29222402:A P1153S missense_variant 0.94 0
2:29222402:C P1153A missense_variant 0.94 0
2:29222402:T P1153T missense_variant 0.94 0
2:29222404:C L1152R missense_variant 0.94 0
2:29222404:G L1152P missense_variant 0.94 0
2:29222404:T L1152Q missense_variant 0.94 0
2:29222407:A T1151M missense_variant 0.94 0
2:29222407:C T1151R missense_variant 0.94 0
2:29222407:T T1151K missense_variant 0.94 0
2:29222524:A A1148V missense_variant 0.94 0
2:29222524:C A1148G missense_variant 0.94 0
2:29222524:T A1148D missense_variant 0.94 0
2:29222536:A P1144L missense_variant 0.94 0
2:29222536:C P1144R missense_variant 0.94 0
2:29222536:T P1144H missense_variant 0.94 0
2:29222576:C Y1131D missense_variant 0.94 0
2:29222576:G Y1131H missense_variant 0.94 0
2:29222576:T Y1131N missense_variant 0.94 0
2:29222578:C V1130G missense_variant 0.94 0
2:29222578:G V1130A missense_variant 0.94 0
2:29222578:T V1130E missense_variant 0.94 0
2:29222587:C F1127C missense_variant 0.94 0
2:29222587:G F1127S missense_variant 0.94 0
2:29222587:T F1127Y missense_variant 0.94 0
2:29222588:C F1127V missense_variant 0.94 0
2:29222588:G F1127L missense_variant 0.94 0
2:29222588:T F1127I missense_variant 0.94 0
2:29222590:A A1126V missense_variant 0.94 0
2:29222590:C A1126G missense_variant 0.94 0
2:29222590:T A1126D missense_variant 0.94 0
2:29222597:A H1124Y missense_variant 0.94 0
2:29222597:C H1124D missense_variant 0.94 0
2:29222597:T H1124N missense_variant 0.94 0
2:29222602:C L1122R missense_variant 0.94 0
2:29222602:G L1122P missense_variant 0.94 0
2:29222602:T L1122Q missense_variant 0.94 0
2:29223349:A L1118F missense_variant 0.94 0
2:29223349:C L1118V missense_variant 0.94 0
2:29207226:C W1295G missense_variant 0.93 0
2:29209811:T F1271I missense_variant 0.93 0
2:29209855:G L1256P missense_variant 0.93 0
2:29209855:C L1256R missense_variant 0.93 0
2:29209859:T C1255S missense_variant 0.93 0
2:29209859:C C1255G missense_variant 0.93 0
2:29209852:G L1257S missense_variant 0.93 0
2:29209828:T V1265E missense_variant 0.93 0
2:29209828:G V1265A missense_variant 0.93 0
2:29209828:C V1265G missense_variant 0.93 0
2:29207240:T M1290K missense_variant 0.93 0
2:29209792:T I1277N missense_variant 0.93 0
2:29209792:G I1277T missense_variant 0.93 0
2:29209792:C I1277S missense_variant 0.93 0
2:29209790:T Y1278N missense_variant 0.93 0
2:29209790:G Y1278H missense_variant 0.93 0
2:29209790:C Y1278D missense_variant 0.93 0
2:29209819:T I1268N missense_variant 0.93 0
2:29209859:G C1255R missense_variant 0.93 0
2:29209804:C M1273R missense_variant 0.93 0
2:29207172:C W1313G missense_variant 0.93 0
2:29207172:G W1313R missense_variant 0.93 0
2:29209855:T L1256H missense_variant 0.93 0
2:29209852:C L1257W missense_variant 0.93 0
2:29209810:C F1271C missense_variant 0.93 0
2:29209873:C I1250S missense_variant 0.93 0
2:29207187:C S1308A missense_variant 0.93 0
2:29207172:T W1313R missense_variant 0.93 0
2:29207187:T S1308T missense_variant 0.93 0
2:29207192:C F1306C missense_variant 0.93 0
2:29209810:G F1271S missense_variant 0.93 0
2:29209810:T F1271Y missense_variant 0.93 0
2:29209811:C F1271V missense_variant 0.93 0
2:29207187:G S1308P missense_variant 0.93 0
2:29207262:C Y1283D missense_variant 0.93 0
2:29207262:G Y1283H missense_variant 0.93 0
2:29207262:T Y1283N missense_variant 0.93 0
2:29209819:G I1268T missense_variant 0.93 0
2:29209819:C I1268S missense_variant 0.93 0
2:29207226:T W1295R missense_variant 0.93 0
2:29207226:G W1295R missense_variant 0.93 0
2:29209811:G F1271L missense_variant 0.93 0
2:29209873:T I1250N missense_variant 0.93 0
2:29207222:T M1296K missense_variant 0.93 0
2:29207192:G F1306S missense_variant 0.93 0
2:29207222:G M1296T missense_variant 0.93 0
2:29207222:C M1296R missense_variant 0.93 0
2:29207240:C M1290R missense_variant 0.93 0
2:29207237:T L1291Q missense_variant 0.93 0
2:29207265:C Y1282D missense_variant 0.93 0
2:29207192:T F1306Y missense_variant 0.93 0
2:29207193:C F1306V missense_variant 0.93 0
2:29207193:G F1306L missense_variant 0.93 0
2:29207193:T F1306I missense_variant 0.93 0
2:29207265:G Y1282H missense_variant 0.93 0
2:29207237:G L1291P missense_variant 0.93 0
2:29209804:T M1273K missense_variant 0.93 0
2:29207195:C I1305R missense_variant 0.93 0
2:29207195:G I1305T missense_variant 0.93 0
2:29207195:T I1305K missense_variant 0.93 0
2:29209873:G I1250T missense_variant 0.93 0
2:29209804:G M1273T missense_variant 0.93 0
2:29207237:C L1291R missense_variant 0.93 0
2:29207231:T V1293D missense_variant 0.93 0
2:29207208:T F1301I missense_variant 0.93 0
2:29207208:G F1301L missense_variant 0.93 0
2:29207208:C F1301V missense_variant 0.93 0
2:29207231:G V1293A missense_variant 0.93 0
2:29207265:T Y1282N missense_variant 0.93 0
2:29207231:C V1293G missense_variant 0.93 0
2:29207207:T F1301Y missense_variant 0.93 0
2:29207207:G F1301S missense_variant 0.93 0
2:29207207:C F1301C missense_variant 0.93 0
2:29207204:T M1302K missense_variant 0.93 0
2:29207204:G M1302T missense_variant 0.93 0
2:29207204:C M1302R missense_variant 0.93 0
2:29207240:G M1290T missense_variant 0.93 0
2:29223348:C L1118R missense_variant 0.93 0
2:29223348:T L1118H missense_variant 0.93 0
2:29223348:G L1118P missense_variant 0.93 0
2:29207239:T M1290I missense_variant 0.92 0
2:29207239:A M1290I missense_variant 0.92 0
2:29207225:G W1295S missense_variant 0.92 0
2:29207225:A W1295L missense_variant 0.92 0
2:29207224:G W1295C missense_variant 0.92 0
2:29207224:A W1295C missense_variant 0.92 0
2:29207221:T M1296I missense_variant 0.92 0
2:29207221:G M1296I missense_variant 0.92 0
2:29207221:A M1296I missense_variant 0.92 0
2:29207214:T E1299K missense_variant 0.92 0
2:29207214:G E1299Q missense_variant 0.92 0
2:29207198:A G1304V missense_variant 0.92 0
2:29207211:T A1300T missense_variant 0.92 0
2:29207211:G A1300P missense_variant 0.92 0
2:29207211:A A1300S missense_variant 0.92 0
2:29207198:G G1304A missense_variant 0.92 0
2:29207198:T G1304E missense_variant 0.92 0
2:29207199:G G1304R missense_variant 0.92 0
2:29207199:T G1304R missense_variant 0.92 0
2:29207202:G E1303Q missense_variant 0.92 0
2:29207202:T E1303K missense_variant 0.92 0
2:29207178:A D1311Y missense_variant 0.92 0
2:29207178:G D1311H missense_variant 0.92 0
2:29207178:T D1311N missense_variant 0.92 0
2:29207171:G W1313S missense_variant 0.92 0
2:29207271:T A1280T missense_variant 0.92 0
2:29207271:G A1280P missense_variant 0.92 0
2:29207271:A A1280S missense_variant 0.92 0
2:29207267:T S1281N missense_variant 0.92 0
2:29207267:G S1281T missense_variant 0.92 0
2:29207267:A S1281I missense_variant 0.92 0
2:29207258:T R1284K missense_variant 0.92 0
2:29207258:G R1284T missense_variant 0.92 0
2:29207258:A R1284I missense_variant 0.92 0
2:29207253:T G1286R missense_variant 0.92 0
2:29207253:G G1286R missense_variant 0.92 0
2:29207252:T G1286E missense_variant 0.92 0
2:29207252:G G1286A missense_variant 0.92 0
2:29207252:A G1286V missense_variant 0.92 0
2:29207250:T G1287S missense_variant 0.92 0
2:29207250:G G1287R missense_variant 0.92 0
2:29207250:A G1287C missense_variant 0.92 0
2:29207249:T G1287D missense_variant 0.92 0
2:29207249:G G1287A missense_variant 0.92 0
2:29207249:A G1287V missense_variant 0.92 0
2:29207246:T C1288Y missense_variant 0.92 0
2:29207246:G C1288S missense_variant 0.92 0
2:29207246:A C1288F missense_variant 0.92 0
2:29207244:T A1289T missense_variant 0.92 0
2:29207244:G A1289P missense_variant 0.92 0
2:29207244:A A1289S missense_variant 0.92 0
2:29207171:A W1313L missense_variant 0.92 0
2:29207239:G M1290I missense_variant 0.92 0
2:29214007:G L1240F missense_variant 0.92 0
2:29214007:A L1240F missense_variant 0.92 0
2:29220834:A K1173* stop_gained 0.92 0
2:29207229:A K1294* stop_gained 0.92 0
2:29207184:A K1309* stop_gained 0.92 0
2:29207256:A K1285* stop_gained 0.92 0
2:29220738:A K1205* stop_gained 0.92 0
2:29209823:A K1267* stop_gained 0.92 0
2:29197655:T W1320* stop_gained 0.91 0
2:29197656:T W1320* stop_gained 0.91 0
2:29197582:A G1345* stop_gained 0.91 0
2:29196837:T W1366* stop_gained 0.91 0
2:29197597:A E1340* stop_gained 0.91 0
2:29197606:A E1337* stop_gained 0.91 0
2:29222582:A E1129* stop_gained 0.91 0
2:29197669:A G1316* stop_gained 0.91 0
2:29197676:T W1313* stop_gained 0.91 0
2:29214003:A E1242* stop_gained 0.91 0
2:29197639:A G1326* stop_gained 0.91 0
2:29222573:A E1132* stop_gained 0.91 0
2:29197654:A E1321* stop_gained 0.91 0
2:29196836:T W1366* stop_gained 0.91 0
2:29196793:A E1381* stop_gained 0.91 0
2:29222344:T S1172N missense_variant 0.91 0
2:29222344:A S1172I missense_variant 0.91 0
2:29222344:G S1172T missense_variant 0.91 0
2:29209858:T C1255Y missense_variant 0.91 0
2:29209858:A C1255F missense_variant 0.91 0
2:29220794:A S1186I missense_variant 0.91 0
2:29220794:G S1186T missense_variant 0.91 0
2:29220794:T S1186N missense_variant 0.91 0
2:29220800:A G1184V missense_variant 0.91 0
2:29220800:G G1184A missense_variant 0.91 0
2:29220800:T G1184E missense_variant 0.91 0
2:29220801:A G1184W missense_variant 0.91 0
2:29220801:G G1184R missense_variant 0.91 0
2:29220801:T G1184R missense_variant 0.91 0
2:29209846:T C1259Y missense_variant 0.91 0
2:29209846:G C1259S missense_variant 0.91 0
2:29209846:A C1259F missense_variant 0.91 0
2:29220806:A C1182F missense_variant 0.91 0
2:29220806:G C1182S missense_variant 0.91 0
2:29220806:T C1182Y missense_variant 0.91 0
2:29209841:T G1261S missense_variant 0.91 0
2:29209841:G G1261R missense_variant 0.91 0
2:29209841:A G1261C missense_variant 0.91 0
2:29220809:A R1181L missense_variant 0.91 0
2:29220809:G R1181P missense_variant 0.91 0
2:29220809:T R1181H missense_variant 0.91 0
2:29209840:T G1261D missense_variant 0.91 0
2:29209840:G G1261A missense_variant 0.91 0
2:29209840:A G1261V missense_variant 0.91 0
2:29209835:T G1263R missense_variant 0.91 0
2:29209835:G G1263R missense_variant 0.91 0
2:29220813:A V1180F missense_variant 0.91 0
2:29220813:G V1180L missense_variant 0.91 0
2:29220813:T V1180I missense_variant 0.91 0
2:29209831:T R1264K missense_variant 0.91 0
2:29209831:G R1264T missense_variant 0.91 0
2:29209831:A R1264I missense_variant 0.91 0
2:29209826:T A1266T missense_variant 0.91 0
2:29209826:G A1266P missense_variant 0.91 0
2:29209826:A A1266S missense_variant 0.91 0
2:29209817:T G1269R missense_variant 0.91 0
2:29209817:G G1269R missense_variant 0.91 0
2:29209816:T G1269E missense_variant 0.91 0
2:29209816:G G1269A missense_variant 0.91 0
2:29209816:A G1269V missense_variant 0.91 0
2:29209814:T D1270N missense_variant 0.91 0
2:29209814:G D1270H missense_variant 0.91 0
2:29209814:A D1270Y missense_variant 0.91 0
2:29209808:T G1272R missense_variant 0.91 0
2:29209808:G G1272R missense_variant 0.91 0
2:29209808:A G1272W missense_variant 0.91 0
2:29209807:T G1272E missense_variant 0.91 0
2:29209807:G G1272A missense_variant 0.91 0
2:29209807:A G1272V missense_variant 0.91 0
2:29209803:T M1273I missense_variant 0.91 0
2:29209803:G M1273I missense_variant 0.91 0
2:29209803:A M1273I missense_variant 0.91 0
2:29209802:T A1274T missense_variant 0.91 0
2:29209802:G A1274P missense_variant 0.91 0
2:29209802:A A1274S missense_variant 0.91 0
2:29209796:T D1276N missense_variant 0.91 0
2:29209796:G D1276H missense_variant 0.91 0
2:29209796:A D1276Y missense_variant 0.91 0
2:29222360:G E1167Q missense_variant 0.91 0
2:29222360:T E1167K missense_variant 0.91 0
2:29222361:A M1166I missense_variant 0.91 0
2:29222361:G M1166I missense_variant 0.91 0
2:29222361:T M1166I missense_variant 0.91 0
2:29222372:A D1163Y missense_variant 0.91 0
2:29222372:G D1163H missense_variant 0.91 0
2:29222372:T D1163N missense_variant 0.91 0
2:29222378:G E1161Q missense_variant 0.91 0
2:29222378:T E1161K missense_variant 0.91 0
2:29222381:A D1160Y missense_variant 0.91 0
2:29222381:G D1160H missense_variant 0.91 0
2:29222381:T D1160N missense_variant 0.91 0
2:29222387:G E1158Q missense_variant 0.91 0
2:29222387:T E1158K missense_variant 0.91 0
2:29222392:A C1156F missense_variant 0.91 0
2:29222392:G C1156S missense_variant 0.91 0
2:29222392:T C1156Y missense_variant 0.91 0
2:29222399:G E1154Q missense_variant 0.91 0
2:29222399:T E1154K missense_variant 0.91 0
2:29220750:T G1201R missense_variant 0.91 0
2:29220750:G G1201R missense_variant 0.91 0
2:29220750:A G1201W missense_variant 0.91 0
2:29220749:T G1201E missense_variant 0.91 0
2:29220754:A M1199I missense_variant 0.91 0
2:29220754:G M1199I missense_variant 0.91 0
2:29220754:T M1199I missense_variant 0.91 0
2:29220749:G G1201A missense_variant 0.91 0
2:29220749:A G1201V missense_variant 0.91 0
2:29220744:T D1203N missense_variant 0.91 0
2:29220744:G D1203H missense_variant 0.91 0
2:29220744:A D1203Y missense_variant 0.91 0
2:29220725:T R1209Q missense_variant 0.91 0
2:29220725:G R1209P missense_variant 0.91 0
2:29220725:A R1209L missense_variant 0.91 0
2:29220762:G E1197Q missense_variant 0.91 0
2:29220762:T E1197K missense_variant 0.91 0
2:29209877:T D1249N missense_variant 0.91 0
2:29209877:G D1249H missense_variant 0.91 0
2:29209877:A D1249Y missense_variant 0.91 0
2:29209871:T A1251T missense_variant 0.91 0
2:29209871:G A1251P missense_variant 0.91 0
2:29209871:A A1251S missense_variant 0.91 0
2:29209868:T A1252T missense_variant 0.91 0
2:29209868:G A1252P missense_variant 0.91 0
2:29209868:A A1252S missense_variant 0.91 0
2:29209864:T R1253K missense_variant 0.91 0
2:29209864:G R1253T missense_variant 0.91 0
2:29209864:A R1253I missense_variant 0.91 0
2:29209858:G C1255S missense_variant 0.91 0
2:29222519:A K1150* stop_gained 0.90 0
2:29196795:T L1380* stop_gained 0.90 0
2:29222384:A Q1159* stop_gained 0.90 0
2:29197609:A Q1336* stop_gained 0.90 0
2:29196844:A Q1364* stop_gained 0.90 0
2:29214078:A Q1217* stop_gained 0.90 0
2:29196835:A Q1367* stop_gained 0.90 0
2:29209852:T L1257* stop_gained 0.90 0
2:29222525:G A1148P missense_variant 0.89 0
2:29222528:G V1147L missense_variant 0.89 0
2:29222528:T V1147M missense_variant 0.89 0
2:29222525:A A1148S missense_variant 0.89 0
2:29222525:T A1148T missense_variant 0.89 0
2:29222528:A V1147L missense_variant 0.89 0
2:29207224:T W1295* stop_gained 0.88 0
2:29207199:A G1304* stop_gained 0.88 0
2:29207225:T W1295* stop_gained 0.88 0
2:29207171:T W1313* stop_gained 0.88 0
2:29207214:A E1299* stop_gained 0.88 0
2:29207253:A G1286* stop_gained 0.88 0
2:29207202:A E1303* stop_gained 0.88 0
2:29209817:A G1269* stop_gained 0.86 0
2:29209835:A G1263* stop_gained 0.86 0
2:29222399:A E1154* stop_gained 0.86 0
2:29220762:A E1197* stop_gained 0.86 0
2:29222387:A E1158* stop_gained 0.86 0
2:29222360:A E1167* stop_gained 0.86 0
2:29222378:A E1161* stop_gained 0.86 0
2:29223342:G R1120P missense_variant 0.78 0
2:29223342:T R1120Q missense_variant 0.78 0
2:29223342:A R1120L missense_variant 0.78 0
2:29222551:T P1139H missense_variant 0.77 0
2:29222551:A P1139L missense_variant 0.77 0
2:29222551:C P1139R missense_variant 0.77 0
2:29220765:C L1196V missense_variant 0.69 0
2:29209786:T R1279K missense_variant 0.56 0
2:29209786:G R1279T missense_variant 0.56 0
2:29209786:A R1279M missense_variant 0.56 0
2:29197665:G V1317A missense_variant 0.54 0
2:29197665:C V1317G missense_variant 0.54 0
2:29197665:T V1317E missense_variant 0.54 0
2:29220774:G F1193L missense_variant 0.54 0
2:29197648:G F1323L missense_variant 0.54 0
2:29197648:T F1323I missense_variant 0.54 0
2:29220782:T L1190Q missense_variant 0.54 0
2:29220782:C L1190R missense_variant 0.54 0
2:29220774:T F1193I missense_variant 0.54 0
2:29220774:C F1193V missense_variant 0.54 0
2:29197648:C F1323V missense_variant 0.54 0
2:29220782:G L1190P missense_variant 0.54 0
2:29220728:T L1208H missense_variant 0.54 0
2:29220728:G L1208P missense_variant 0.54 0
2:29220728:C L1208R missense_variant 0.54 0
In silico saturation mutagenesis
Alt text Show figure caption
Cancer type Selected cancer type Mutational discovery Index Feature Complexity
(NB) Neuroblastoma NB 0.66 0.14