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Note: You're navigating the results of models obtained with IntOGen (2020). A new boostDM version is available here.
APC PRAD ×
Select a mutation to see further information
Mutation AA change Consequence type BoostDM score IntOGen frequency
5:112839942:T R1450* stop_gained 1.00 3
5:112837938:T K782* stop_gained 1.00 2
5:112838934:T R1114* stop_gained 1.00 2
5:112840215:T Q1541* stop_gained 1.00 2
5:112842570:T R2326* stop_gained 1.00 2
5:112842270:T R2226* stop_gained 1.00 2
5:112840131:T E1513* stop_gained 1.00 1
5:112840311:T E1573* stop_gained 1.00 1
5:112840200:T E1536* stop_gained 1.00 1
5:112838832:T E1080* stop_gained 1.00 1
5:112840272:T E1560* stop_gained 1.00 1
5:112840159:G L1522* stop_gained 1.00 1
5:112840294:A S1567* stop_gained 1.00 1
5:112839793:A S1400* stop_gained 1.00 1
5:112840143:T Q1517* stop_gained 1.00 1
5:112838961:T Q1123* stop_gained 1.00 1
5:112839538:A S1315* stop_gained 1.00 1
5:112840210:G S1539* stop_gained 1.00 1
5:112838220:T R876* stop_gained 1.00 1
5:112840320:T E1576* stop_gained 0.99 1
5:112841896:A W2101* stop_gained 1.00 0
5:112840074:T E1494* stop_gained 1.00 0
5:112838298:T E902* stop_gained 1.00 0
5:112839876:T G1428* stop_gained 1.00 0
5:112837905:T E771* stop_gained 1.00 0
5:112837649:A W685* stop_gained 1.00 0
5:112838346:T E918* stop_gained 1.00 0
5:112837690:A W699* stop_gained 1.00 0
5:112837691:A W699* stop_gained 1.00 0
5:112839387:T E1265* stop_gained 1.00 0
5:112839363:T E1257* stop_gained 1.00 0
5:112838133:T E847* stop_gained 1.00 0
5:112838415:T E941* stop_gained 1.00 0
5:112840527:T E1645* stop_gained 1.00 0
5:112842216:T E2208* stop_gained 1.00 0
5:112837755:T G721* stop_gained 1.00 0
5:112838325:T E911* stop_gained 1.00 0
5:112840596:T E1668* stop_gained 1.00 0
5:112837566:T E658* stop_gained 1.00 0
5:112841910:T E2106* stop_gained 1.00 0
5:112842165:T G2191* stop_gained 1.00 0
5:112838268:T E892* stop_gained 1.00 0
5:112838271:T E893* stop_gained 1.00 0
5:112841897:A W2101* stop_gained 1.00 0
5:112842108:T E2172* stop_gained 1.00 0
5:112842123:T E2177* stop_gained 1.00 0
5:112842162:T G2190* stop_gained 1.00 0
5:112837648:A W685* stop_gained 1.00 0
5:112841526:T E1978* stop_gained 1.00 0
5:112837638:T G682* stop_gained 1.00 0
5:112837881:T E763* stop_gained 1.00 0
5:112838457:T E955* stop_gained 1.00 0
5:112841697:T E2035* stop_gained 1.00 0
5:112837680:T E696* stop_gained 1.00 0
5:112838652:T E1020* stop_gained 1.00 0
5:112841637:T E2015* stop_gained 1.00 0
5:112841439:T E1949* stop_gained 1.00 0
5:112842027:T G2145* stop_gained 1.00 0
5:112838694:T E1034* stop_gained 1.00 0
5:112843557:T E2655* stop_gained 1.00 0
5:112840770:T E1726* stop_gained 1.00 0
5:112842015:T G2141* stop_gained 1.00 0
5:112843359:T E2589* stop_gained 1.00 0
5:112843286:A W2564* stop_gained 1.00 0
5:112843338:T E2582* stop_gained 1.00 0
5:112843329:T E2579* stop_gained 1.00 0
5:112843422:T G2610* stop_gained 1.00 0
5:112843429:A W2612* stop_gained 1.00 0
5:112843430:A W2612* stop_gained 1.00 0
5:112842930:T E2446* stop_gained 1.00 0
5:112838151:T E853* stop_gained 1.00 0
5:112843567:A W2658* stop_gained 1.00 0
5:112843568:A W2658* stop_gained 1.00 0
5:112843578:T E2662* stop_gained 1.00 0
5:112841145:T G1851* stop_gained 1.00 0
5:112841142:T E1850* stop_gained 1.00 0
5:112843227:T G2545* stop_gained 1.00 0
5:112842966:T E2458* stop_gained 1.00 0
5:112842963:T E2457* stop_gained 1.00 0
5:112841250:T E1886* stop_gained 1.00 0
5:112842891:T E2433* stop_gained 1.00 0
5:112842876:T E2428* stop_gained 1.00 0
5:112842819:T G2409* stop_gained 1.00 0
5:112843106:A W2504* stop_gained 1.00 0
5:112841100:T G1836* stop_gained 1.00 0
5:112841622:T K2010* stop_gained 1.00 0
5:112837866:T K758* stop_gained 1.00 0
5:112838517:T K975* stop_gained 1.00 0
5:112837860:T K756* stop_gained 1.00 0
5:112837806:T K738* stop_gained 1.00 0
5:112841739:T K2049* stop_gained 1.00 0
5:112841745:T K2051* stop_gained 1.00 0
5:112841748:T K2052* stop_gained 1.00 0
5:112841898:T K2102* stop_gained 1.00 0
5:112842171:T K2193* stop_gained 1.00 0
5:112839903:T K1437* stop_gained 1.00 0
5:112842009:T K2139* stop_gained 1.00 0
5:112837740:T K716* stop_gained 1.00 0
5:112840350:T K1586* stop_gained 1.00 0
5:112840440:T K1616* stop_gained 1.00 0
5:112840416:T K1608* stop_gained 1.00 0
5:112842198:T K2202* stop_gained 1.00 0
5:112841442:T K1950* stop_gained 1.00 0
5:112838532:T K980* stop_gained 1.00 0
5:112838682:T K1030* stop_gained 1.00 0
5:112841265:T E1891* stop_gained 1.00 0
5:112842129:T K2179* stop_gained 1.00 0
5:112840794:T K1734* stop_gained 1.00 0
5:112843434:T K2614* stop_gained 1.00 0
5:112843440:T K2616* stop_gained 1.00 0
5:112840800:T K1736* stop_gained 1.00 0
5:112840899:T K1769* stop_gained 1.00 0
5:112840905:T K1771* stop_gained 1.00 0
5:112838613:T K1007* stop_gained 1.00 0
5:112843251:T K2553* stop_gained 1.00 0
5:112842957:T K2455* stop_gained 1.00 0
5:112842927:T K2445* stop_gained 1.00 0
5:112840902:T K1770* stop_gained 1.00 0
5:112842894:T R2434* stop_gained 1.00 0
5:112843449:T E2619* stop_gained 1.00 0
5:112839099:T E1169* stop_gained 1.00 0
5:112843443:T E2617* stop_gained 1.00 0
5:112839729:T E1379* stop_gained 1.00 0
5:112839714:T E1374* stop_gained 1.00 0
5:112839444:T E1284* stop_gained 1.00 0
5:112838709:T G1039* stop_gained 1.00 0
5:112840923:T K1777* stop_gained 1.00 0
5:112842132:T K2180* stop_gained 1.00 0
5:112843551:T K2653* stop_gained 1.00 0
5:112839669:T K1359* stop_gained 1.00 0
5:112839450:T E1286* stop_gained 1.00 0
5:112839327:T K1245* stop_gained 1.00 0
5:112839168:T K1192* stop_gained 1.00 0
5:112839138:T K1182* stop_gained 1.00 0
5:112840182:T E1530* stop_gained 1.00 0
5:112841055:T K1821* stop_gained 1.00 0
5:112842837:T E2415* stop_gained 1.00 0
5:112843140:T E2516* stop_gained 1.00 0
5:112839000:T E1136* stop_gained 1.00 0
5:112839039:T E1149* stop_gained 1.00 0
5:112839042:T E1150* stop_gained 1.00 0
5:112839045:T E1151* stop_gained 1.00 0
5:112839054:T E1154* stop_gained 1.00 0
5:112839057:T E1155* stop_gained 1.00 0
5:112841859:T E2089* stop_gained 1.00 0
5:112843866:T E2758* stop_gained 1.00 0
5:112838740:A W1049* stop_gained 1.00 0
5:112842501:T G2303* stop_gained 1.00 0
5:112842597:T G2335* stop_gained 1.00 0
5:112844049:T K2819* stop_gained 1.00 0
5:112844037:T K2815* stop_gained 1.00 0
5:112844073:T G2827* stop_gained 1.00 0
5:112838769:T E1059* stop_gained 1.00 0
5:112838763:T E1057* stop_gained 1.00 0
5:112843842:T E2750* stop_gained 1.00 0
5:112843797:T G2735* stop_gained 1.00 0
5:112843749:T E2719* stop_gained 1.00 0
5:112843968:T K2792* stop_gained 1.00 0
5:112838733:T E1047* stop_gained 1.00 0
5:112838988:T E1132* stop_gained 1.00 0
5:112838925:T E1111* stop_gained 1.00 0
5:112844064:T E2824* stop_gained 1.00 0
5:112842831:T K2413* stop_gained 1.00 0
5:112841715:T E2041* stop_gained 1.00 0
5:112837591:G L666* stop_gained 1.00 0
5:112837600:A L669* stop_gained 1.00 0
5:112837600:G L669* stop_gained 1.00 0
5:112837591:A L666* stop_gained 1.00 0
5:112837615:A L674* stop_gained 1.00 0
5:112837588:G L665* stop_gained 1.00 0
5:112837645:A L684* stop_gained 1.00 0
5:112837588:A L665* stop_gained 1.00 0
5:112840057:A L1488* stop_gained 1.00 0
5:112840060:G L1489* stop_gained 1.00 0
5:112837687:A L698* stop_gained 1.00 0
5:112837687:G L698* stop_gained 1.00 0
5:112840057:G L1488* stop_gained 1.00 0
5:112837771:A L726* stop_gained 1.00 0
5:112837771:G L726* stop_gained 1.00 0
5:112840060:A L1489* stop_gained 1.00 0
5:112839433:A L1280* stop_gained 1.00 0
5:112838485:A L964* stop_gained 1.00 0
5:112838485:G L964* stop_gained 1.00 0
5:112837885:A L764* stop_gained 1.00 0
5:112837885:G L764* stop_gained 1.00 0
5:112837900:A L769* stop_gained 1.00 0
5:112837900:G L769* stop_gained 1.00 0
5:112841938:A L2115* stop_gained 1.00 0
5:112841938:G L2115* stop_gained 1.00 0
5:112839424:G L1277* stop_gained 1.00 0
5:112838071:A L826* stop_gained 1.00 0
5:112840159:A L1522* stop_gained 1.00 0
5:112839424:A L1277* stop_gained 1.00 0
5:112841463:T E1957* stop_gained 1.00 0
5:112840089:T G1499* stop_gained 1.00 0
5:112841883:T E2097* stop_gained 1.00 0
5:112840146:T K1518* stop_gained 1.00 0
5:112840323:T E1577* stop_gained 1.00 0
5:112840155:T E1521* stop_gained 1.00 0
5:112842195:T G2201* stop_gained 1.00 0
5:112839816:T E1408* stop_gained 1.00 0
5:112842187:A L2198* stop_gained 1.00 0
5:112839456:T G1288* stop_gained 1.00 0
5:112838775:T K1061* stop_gained 1.00 0
5:112839663:T G1357* stop_gained 1.00 0
5:112842297:T G2235* stop_gained 1.00 0
5:112841710:A L2039* stop_gained 1.00 0
5:112841626:G S2011* stop_gained 1.00 0
5:112840102:A S1503* stop_gained 1.00 0
5:112840102:G S1503* stop_gained 1.00 0
5:112839879:T Q1429* stop_gained 1.00 0
5:112840294:G S1567* stop_gained 1.00 0
5:112840357:A S1588* stop_gained 1.00 0
5:112840357:G S1588* stop_gained 1.00 0
5:112840425:T Q1611* stop_gained 1.00 0
5:112837554:T Q654* stop_gained 1.00 0
5:112837593:T Q667* stop_gained 1.00 0
5:112837657:A S688* stop_gained 1.00 0
5:112837657:G S688* stop_gained 1.00 0
5:112837677:T Q695* stop_gained 1.00 0
5:112839436:G S1281* stop_gained 1.00 0
5:112837732:A S713* stop_gained 1.00 0
5:112837732:G S713* stop_gained 1.00 0
5:112839436:A S1281* stop_gained 1.00 0
5:112837834:A S747* stop_gained 1.00 0
5:112837834:G S747* stop_gained 1.00 0
5:112837863:T Q757* stop_gained 1.00 0
5:112837903:A S770* stop_gained 1.00 0
5:112837903:G S770* stop_gained 1.00 0
5:112839427:G S1278* stop_gained 1.00 0
5:112837959:T Q789* stop_gained 1.00 0
5:112839427:A S1278* stop_gained 1.00 0
5:112837971:T Q793* stop_gained 1.00 0
5:112839421:G S1276* stop_gained 1.00 0
5:112838026:A S811* stop_gained 1.00 0
5:112838026:G S811* stop_gained 1.00 0
5:112838062:A S823* stop_gained 1.00 0
5:112838062:G S823* stop_gained 1.00 0
5:112839421:A S1276* stop_gained 1.00 0
5:112839409:G S1272* stop_gained 1.00 0
5:112842013:G S2140* stop_gained 1.00 0
5:112842013:A S2140* stop_gained 1.00 0
5:112839409:A S1272* stop_gained 1.00 0
5:112839372:T Q1260* stop_gained 1.00 0
5:112839360:T Q1256* stop_gained 1.00 0
5:112841989:G S2132* stop_gained 1.00 0
5:112841989:A S2132* stop_gained 1.00 0
5:112841980:A S2129* stop_gained 1.00 0
5:112841907:T Q2105* stop_gained 1.00 0
5:112838473:A S960* stop_gained 1.00 0
5:112838473:G S960* stop_gained 1.00 0
5:112841659:G S2022* stop_gained 1.00 0
5:112841659:A S2022* stop_gained 1.00 0
5:112841626:A S2011* stop_gained 1.00 0
5:112838649:T G1019* stop_gained 1.00 0
5:112841448:T Q1952* stop_gained 1.00 0
5:112839661:A S1356* stop_gained 1.00 0
5:112839769:G S1392* stop_gained 1.00 0
5:112839769:A S1392* stop_gained 1.00 0
5:112839439:G S1282* stop_gained 1.00 0
5:112839439:A S1282* stop_gained 1.00 0
5:112839661:G S1356* stop_gained 1.00 0
5:112841814:T E2074* stop_gained 1.00 0
5:112838544:T E984* stop_gained 1.00 0
5:112838565:T E991* stop_gained 1.00 0
5:112843296:T G2568* stop_gained 1.00 0
5:112843353:T E2587* stop_gained 1.00 0
5:112843285:A W2564* stop_gained 1.00 0
5:112839975:T E1461* stop_gained 1.00 0
5:112841712:T Q2040* stop_gained 1.00 0
5:112840233:T E1547* stop_gained 1.00 0
5:112842949:G L2452* stop_gained 1.00 0
5:112842904:A L2437* stop_gained 1.00 0
5:112842904:G L2437* stop_gained 1.00 0
5:112842961:A L2456* stop_gained 1.00 0
5:112842949:A L2452* stop_gained 1.00 0
5:112841179:A L1862* stop_gained 1.00 0
5:112838701:A L1036* stop_gained 1.00 0
5:112839009:T K1139* stop_gained 1.00 0
5:112840392:T K1600* stop_gained 1.00 0
5:112841847:T R2085* stop_gained 1.00 0
5:112842981:T E2463* stop_gained 1.00 0
5:112841223:T E1877* stop_gained 1.00 0
5:112842499:G S2302* stop_gained 1.00 0
5:112842499:A S2302* stop_gained 1.00 0
5:112839783:T E1397* stop_gained 1.00 0
5:112841325:T Q1911* stop_gained 1.00 0
5:112838689:G S1032* stop_gained 1.00 0
5:112838697:T Q1035* stop_gained 1.00 0
5:112843309:A S2572* stop_gained 1.00 0
5:112843327:G S2578* stop_gained 1.00 0
5:112843327:A S2578* stop_gained 1.00 0
5:112838689:A S1032* stop_gained 1.00 0
5:112843309:G S2572* stop_gained 1.00 0
5:112842031:A S2146* stop_gained 1.00 0
5:112843261:G S2556* stop_gained 1.00 0
5:112843324:A S2577* stop_gained 1.00 0
5:112843261:A S2556* stop_gained 1.00 0
5:112842031:G S2146* stop_gained 1.00 0
5:112843324:G S2577* stop_gained 1.00 0
5:112839681:T K1363* stop_gained 1.00 0
5:112838856:T K1088* stop_gained 1.00 0
5:112842057:T E2155* stop_gained 1.00 0
5:112841119:A S1842* stop_gained 1.00 0
5:112841586:T E1998* stop_gained 1.00 0
5:112842916:G S2441* stop_gained 1.00 0
5:112842916:A S2441* stop_gained 1.00 0
5:112842912:T Q2440* stop_gained 1.00 0
5:112841164:G S1857* stop_gained 1.00 0
5:112841164:A S1857* stop_gained 1.00 0
5:112838157:T E855* stop_gained 1.00 0
5:112841119:G S1842* stop_gained 1.00 0
5:112838715:T Q1041* stop_gained 1.00 0
5:112842777:T E2395* stop_gained 1.00 0
5:112839981:T R1463* stop_gained 1.00 0
5:112840248:T E1552* stop_gained 1.00 0
5:112838109:T G839* stop_gained 1.00 0
5:112843362:T K2590* stop_gained 1.00 0
5:112841556:T K1988* stop_gained 1.00 0
5:112843290:T R2566* stop_gained 1.00 0
5:112841608:A S2005* stop_gained 1.00 0
5:112841608:G S2005* stop_gained 1.00 0
5:112842619:G L2342* stop_gained 1.00 0
5:112842619:A L2342* stop_gained 1.00 0
5:112843509:T E2639* stop_gained 1.00 0
5:112843513:A S2640* stop_gained 1.00 0
5:112843513:G S2640* stop_gained 1.00 0
5:112843287:T R2565* stop_gained 1.00 0
5:112840701:T G1703* stop_gained 1.00 0
5:112842204:T R2204* stop_gained 1.00 0
5:112842228:T Q2212* stop_gained 1.00 0
5:112841844:T Q2084* stop_gained 1.00 0
5:112841757:T R2055* stop_gained 1.00 0
5:112843045:G L2484* stop_gained 1.00 0
5:112843045:A L2484* stop_gained 1.00 0
5:112842507:T R2305* stop_gained 1.00 0
5:112838154:T R854* stop_gained 1.00 0
5:112842234:T K2214* stop_gained 1.00 0
5:112842771:T R2393* stop_gained 1.00 0
5:112840695:T Q1701* stop_gained 1.00 0
5:112840465:A L1624* stop_gained 1.00 0
5:112841833:A L2080* stop_gained 1.00 0
5:112838163:T G857* stop_gained 1.00 0
5:112838589:T Q999* stop_gained 1.00 0
5:112843489:G S2632* stop_gained 1.00 0
5:112843489:A S2632* stop_gained 1.00 0
5:112840728:T E1712* stop_gained 1.00 0
5:112840749:T E1719* stop_gained 1.00 0
5:112842865:A S2424* stop_gained 1.00 0
5:112842865:G S2424* stop_gained 1.00 0
5:112842856:A S2421* stop_gained 1.00 0
5:112842856:G S2421* stop_gained 1.00 0
5:112843234:A W2547* stop_gained 1.00 0
5:112839810:T Q1406* stop_gained 1.00 0
5:112843164:T K2524* stop_gained 1.00 0
5:112841236:A L1881* stop_gained 1.00 0
5:112841236:G L1881* stop_gained 1.00 0
5:112843686:T K2698* stop_gained 1.00 0
5:112838973:T Q1127* stop_gained 1.00 0
5:112842054:T Q2154* stop_gained 1.00 0
5:112838793:T Q1067* stop_gained 1.00 0
5:112841304:T Q1904* stop_gained 1.00 0
5:112843235:A W2547* stop_gained 1.00 0
5:112841379:T K1929* stop_gained 1.00 0
5:112839538:G S1315* stop_gained 1.00 0
5:112840896:T K1768* stop_gained 1.00 0
5:112839324:T Q1244* stop_gained 1.00 0
5:112840962:T R1790* stop_gained 1.00 0
5:112843815:T G2741* stop_gained 1.00 0
5:112842237:T Q2215* stop_gained 1.00 0
5:112840245:T K1551* stop_gained 1.00 0
5:112839201:T G1203* stop_gained 1.00 0
5:112843107:T R2505* stop_gained 1.00 0
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5:112838278:A S895* stop_gained 0.99 0
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5:112827110:T G471* stop_gained 0.79 0
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5:112827992:T E538* stop_gained 0.78 0
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5:112755023:T K45* stop_gained 0.77 0
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5:112766410:T E74* stop_gained 0.77 0
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5:112766407:T K73* stop_gained 0.75 0
5:112766335:T K49* stop_gained 0.75 0
5:112819111:G L360* stop_gained 0.74 0
5:112819033:A L334* stop_gained 0.74 0
5:112818985:A L318* stop_gained 0.74 0
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5:112827132:G L478* stop_gained 0.74 0
5:112827132:A L478* stop_gained 0.74 0
5:112819284:T E418* stop_gained 0.74 0
5:112819212:T Q394* stop_gained 0.73 0
5:112818991:A S320* stop_gained 0.73 0
5:112818991:G S320* stop_gained 0.73 0
5:112819024:A S331* stop_gained 0.73 0
5:112819053:T Q341* stop_gained 0.73 0
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5:112819104:T Q358* stop_gained 0.73 0
5:112819266:T Q412* stop_gained 0.73 0
5:112821916:T Q445* stop_gained 0.73 0
5:112821953:A S457* stop_gained 0.73 0
5:112821953:G S457* stop_gained 0.73 0
5:112827116:T Q473* stop_gained 0.73 0
5:112827137:T Q480* stop_gained 0.73 0
5:112767371:T E135* stop_gained 0.73 0
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5:112767374:T E136* stop_gained 0.73 0
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5:112767344:T G126* stop_gained 0.73 0
5:112767218:T G84* stop_gained 0.73 0
5:112767353:T E129* stop_gained 0.73 0
5:112767386:T E140* stop_gained 0.73 0
5:112767269:T G101* stop_gained 0.73 0
5:112835141:A L645* stop_gained 0.66 0
5:112828959:G L577* stop_gained 0.66 0
5:112828959:A L577* stop_gained 0.66 0
5:112828917:A L563* stop_gained 0.66 0
5:112834982:A L592* stop_gained 0.66 0
5:112834982:G L592* stop_gained 0.66 0
5:112834973:A L589* stop_gained 0.66 0
5:112834991:A L595* stop_gained 0.66 0
5:112835054:A L616* stop_gained 0.66 0
5:112835155:T E650* stop_gained 0.66 0
5:112827999:A L540* stop_gained 0.65 0
5:112828881:A L551* stop_gained 0.65 0
5:112828872:A L548* stop_gained 0.65 0
5:112827999:G L540* stop_gained 0.65 0
5:112835093:G L629* stop_gained 0.63 0
5:112835093:A L629* stop_gained 0.63 0
5:112835123:G L639* stop_gained 0.63 0
5:112835123:A L639* stop_gained 0.63 0
5:112834994:A S596* stop_gained 0.62 0
5:112834955:G S583* stop_gained 0.62 0
5:112834994:G S596* stop_gained 0.62 0
5:112834955:A S583* stop_gained 0.62 0
5:112827974:T Q532* stop_gained 0.60 0
5:112828004:T Q542* stop_gained 0.60 0
5:112754919:G L10* stop_gained 0.57 0
5:112754916:A L9* stop_gained 0.57 0
5:112754919:A L10* stop_gained 0.57 0
5:112819224:T K398* stop_gained 0.52 0
5:112835080:T Q625* stop_gained 0.52 0
In silico saturation mutagenesis
Alt text Show figure caption
Cancer type Selected cancer type Mutational discovery Index Feature Complexity
(PRAD) Prostate adenocarcinoma PRAD 0.49 0.09