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Note: You're navigating the results of models obtained with IntOGen (2020). A new boostDM version is available here.
ERCC2 BLCA ×
Select a mutation to see further information
Mutation AA change Consequence type BoostDM score IntOGen frequency
19:45364429:C N238S missense_variant 1.00 14
19:45369122:A S44L missense_variant 1.00 8
19:45368734:G E86Q missense_variant 1.00 6
19:45357298:A T484M missense_variant 1.00 5
19:45368961:C Y72C missense_variant 0.98 5
19:45357299:C T484A missense_variant 1.00 2
19:45368955:A S74L missense_variant 0.99 2
19:45368952:T R75K missense_variant 0.99 2
19:45352577:A H659Y missense_variant 0.98 2
19:45370170:C S23C missense_variant 0.90 2
19:45370197:C Y14C missense_variant 0.73 2
19:45369129:C M42V missense_variant 0.69 2
19:45364516:C Y209C missense_variant 0.98 1
19:45364313:T S246Y missense_variant 0.97 1
19:45364313:A S246F missense_variant 0.97 1
19:45357361:A P463L missense_variant 0.96 1
19:45357362:A P463S missense_variant 0.96 1
19:45368937:G I80T missense_variant 0.96 1
19:45368638:A H118Y missense_variant 0.91 1
19:45357523:A A443V missense_variant 0.87 1
19:45351640:C Q758E missense_variant 0.85 1
19:45354735:G E554Q missense_variant 0.79 1
19:45352529:T G675S missense_variant 0.66 1
19:45353094:G G607A missense_variant 0.57 1
19:45357298:C T484R missense_variant 1.00 0
19:45357298:T T484K missense_variant 1.00 0
19:45368734:T E86K missense_variant 1.00 0
19:45364429:G N238T missense_variant 1.00 0
19:45364429:A N238I missense_variant 1.00 0
19:45357299:G T484P missense_variant 1.00 0
19:45357299:A T484S missense_variant 1.00 0
19:45368962:G Y72H missense_variant 0.99 0
19:45368962:C Y72D missense_variant 0.99 0
19:45368962:T Y72N missense_variant 0.99 0
19:45364517:G Y209H missense_variant 0.99 0
19:45364517:C Y209D missense_variant 0.99 0
19:45364517:T Y209N missense_variant 0.99 0
19:45368952:G R75T missense_variant 0.99 0
19:45368952:A R75I missense_variant 0.99 0
19:45368961:A Y72F missense_variant 0.98 0
19:45368961:G Y72S missense_variant 0.98 0
19:45365100:T S140Y missense_variant 0.98 0
19:45365100:A S140F missense_variant 0.98 0
19:45364283:C L256R missense_variant 0.98 0
19:45364283:G L256P missense_variant 0.98 0
19:45364283:T L256H missense_variant 0.98 0
19:45365100:C S140C missense_variant 0.98 0
19:45365103:T A139D missense_variant 0.98 0
19:45365103:A A139V missense_variant 0.98 0
19:45365103:C A139G missense_variant 0.98 0
19:45352577:T H659N missense_variant 0.98 0
19:45352577:C H659D missense_variant 0.98 0
19:45364516:G Y209S missense_variant 0.98 0
19:45364516:A Y209F missense_variant 0.98 0
19:45364546:G I199T missense_variant 0.98 0
19:45364546:T I199N missense_variant 0.98 0
19:45364546:C I199S missense_variant 0.98 0
19:45364902:C L177R missense_variant 0.97 0
19:45364902:T L177Q missense_variant 0.97 0
19:45364902:G L177P missense_variant 0.97 0
19:45368946:G V77A missense_variant 0.97 0
19:45368959:T C73S missense_variant 0.97 0
19:45368959:G C73R missense_variant 0.97 0
19:45368959:C C73G missense_variant 0.97 0
19:45364478:G S222P missense_variant 0.97 0
19:45364478:C S222A missense_variant 0.97 0
19:45368946:T V77E missense_variant 0.97 0
19:45364478:T S222T missense_variant 0.97 0
19:45368946:C V77G missense_variant 0.97 0
19:45368956:G S74P missense_variant 0.97 0
19:45368956:T S74T missense_variant 0.97 0
19:45368956:C S74A missense_variant 0.97 0
19:45365101:G S140P missense_variant 0.97 0
19:45365101:C S140A missense_variant 0.97 0
19:45365101:T S140T missense_variant 0.97 0
19:45364313:C S246C missense_variant 0.97 0
19:45365050:T F157I missense_variant 0.97 0
19:45365050:C F157V missense_variant 0.97 0
19:45365050:G F157L missense_variant 0.97 0
19:45368721:C L90W missense_variant 0.97 0
19:45368739:T I84N missense_variant 0.97 0
19:45368739:G I84T missense_variant 0.97 0
19:45368739:C I84S missense_variant 0.97 0
19:45368730:T L87H missense_variant 0.97 0
19:45368730:G L87P missense_variant 0.97 0
19:45368730:C L87R missense_variant 0.97 0
19:45368713:C F93V missense_variant 0.97 0
19:45368713:G F93L missense_variant 0.97 0
19:45368713:T F93I missense_variant 0.97 0
19:45368718:C L91R missense_variant 0.97 0
19:45368718:G L91P missense_variant 0.97 0
19:45368718:T L91H missense_variant 0.97 0
19:45368721:G L90S missense_variant 0.97 0
19:45352600:T F651Y missense_variant 0.96 0
19:45352637:T Y639N missense_variant 0.96 0
19:45352642:C L637R missense_variant 0.96 0
19:45352642:G L637P missense_variant 0.96 0
19:45357368:T L461M missense_variant 0.96 0
19:45352642:T L637Q missense_variant 0.96 0
19:45357361:C P463R missense_variant 0.96 0
19:45357370:A T460I missense_variant 0.96 0
19:45357370:C T460R missense_variant 0.96 0
19:45357370:T T460K missense_variant 0.96 0
19:45352615:T I646N missense_variant 0.96 0
19:45357361:T P463Q missense_variant 0.96 0
19:45352637:C Y639D missense_variant 0.96 0
19:45352637:G Y639H missense_variant 0.96 0
19:45352601:T F651I missense_variant 0.96 0
19:45357362:C P463A missense_variant 0.96 0
19:45352601:C F651V missense_variant 0.96 0
19:45357364:A S462F missense_variant 0.96 0
19:45357364:C S462C missense_variant 0.96 0
19:45352601:G F651L missense_variant 0.96 0
19:45357362:T P463T missense_variant 0.96 0
19:45357364:T S462Y missense_variant 0.96 0
19:45357368:C L461V missense_variant 0.96 0
19:45352600:G F651S missense_variant 0.96 0
19:45352600:C F651C missense_variant 0.96 0
19:45352615:C I646S missense_variant 0.96 0
19:45352615:G I646T missense_variant 0.96 0
19:45368676:C L105R missense_variant 0.96 0
19:45368659:T S111T missense_variant 0.96 0
19:45368670:T L107Q missense_variant 0.96 0
19:45368659:G S111P missense_variant 0.96 0
19:45368659:C S111A missense_variant 0.96 0
19:45368670:G L107P missense_variant 0.96 0
19:45368670:C L107R missense_variant 0.96 0
19:45368664:T L109Q missense_variant 0.96 0
19:45368664:G L109P missense_variant 0.96 0
19:45368676:T L105Q missense_variant 0.96 0
19:45368664:C L109R missense_variant 0.96 0
19:45368680:G F104L missense_variant 0.96 0
19:45368680:C F104V missense_variant 0.96 0
19:45368676:G L105P missense_variant 0.96 0
19:45368680:T F104I missense_variant 0.96 0
19:45361553:T F403Y missense_variant 0.96 0
19:45361553:C F403C missense_variant 0.96 0
19:45361544:T L406H missense_variant 0.96 0
19:45361625:T L379H missense_variant 0.96 0
19:45361625:G L379P missense_variant 0.96 0
19:45361625:C L379R missense_variant 0.96 0
19:45361640:C F374C missense_variant 0.96 0
19:45361620:T S381T missense_variant 0.96 0
19:45361620:G S381P missense_variant 0.96 0
19:45361640:G F374S missense_variant 0.96 0
19:45361620:C S381A missense_variant 0.96 0
19:45361616:T L382Q missense_variant 0.96 0
19:45361616:G L382P missense_variant 0.96 0
19:45361616:C L382R missense_variant 0.96 0
19:45361604:T L386Q missense_variant 0.96 0
19:45361604:G L386P missense_variant 0.96 0
19:45361604:C L386R missense_variant 0.96 0
19:45361598:T I388N missense_variant 0.96 0
19:45361640:T F374Y missense_variant 0.96 0
19:45361598:G I388T missense_variant 0.96 0
19:45361598:C I388S missense_variant 0.96 0
19:45361589:T L391H missense_variant 0.96 0
19:45361589:G L391P missense_variant 0.96 0
19:45361589:C L391R missense_variant 0.96 0
19:45361541:G V407A missense_variant 0.96 0
19:45361541:T V407D missense_variant 0.96 0
19:45361571:T L397H missense_variant 0.96 0
19:45361571:G L397P missense_variant 0.96 0
19:45361571:C L397R missense_variant 0.96 0
19:45361544:C L406R missense_variant 0.96 0
19:45361544:G L406P missense_variant 0.96 0
19:45361565:T L399H missense_variant 0.96 0
19:45361565:G L399P missense_variant 0.96 0
19:45361565:C L399R missense_variant 0.96 0
19:45361562:T L400H missense_variant 0.96 0
19:45361562:G L400P missense_variant 0.96 0
19:45361638:C C375G missense_variant 0.96 0
19:45361638:G C375R missense_variant 0.96 0
19:45361638:T C375S missense_variant 0.96 0
19:45361562:C L400R missense_variant 0.96 0
19:45361554:T F403I missense_variant 0.96 0
19:45361554:G F403L missense_variant 0.96 0
19:45361554:C F403V missense_variant 0.96 0
19:45361553:G F403S missense_variant 0.96 0
19:45361533:C Y410D missense_variant 0.96 0
19:45361533:G Y410H missense_variant 0.96 0
19:45361533:T Y410N missense_variant 0.96 0
19:45361580:T F394Y missense_variant 0.96 0
19:45361580:G F394S missense_variant 0.96 0
19:45361580:C F394C missense_variant 0.96 0
19:45361541:C V407G missense_variant 0.96 0
19:45368937:T I80N missense_variant 0.96 0
19:45368937:C I80S missense_variant 0.96 0
19:45357639:C L433R missense_variant 0.95 0
19:45357654:G I428T missense_variant 0.95 0
19:45357654:C I428S missense_variant 0.95 0
19:45357639:T L433Q missense_variant 0.95 0
19:45357675:T F421Y missense_variant 0.95 0
19:45357697:C F414V missense_variant 0.95 0
19:45357697:G F414L missense_variant 0.95 0
19:45357697:T F414I missense_variant 0.95 0
19:45357654:T I428N missense_variant 0.95 0
19:45357675:G F421S missense_variant 0.95 0
19:45357675:C F421C missense_variant 0.95 0
19:45357639:G L433P missense_variant 0.95 0
19:45365148:C L124R missense_variant 0.95 0
19:45365157:C V121G missense_variant 0.95 0
19:45365148:G L124P missense_variant 0.95 0
19:45365148:T L124Q missense_variant 0.95 0
19:45365157:T V121E missense_variant 0.95 0
19:45365157:G V121A missense_variant 0.95 0
19:45368640:T I117N missense_variant 0.95 0
19:45368646:G L115S missense_variant 0.95 0
19:45368646:C L115W missense_variant 0.95 0
19:45368644:T C116S missense_variant 0.95 0
19:45368644:G C116R missense_variant 0.95 0
19:45368644:C C116G missense_variant 0.95 0
19:45368640:G I117T missense_variant 0.95 0
19:45368640:C I117S missense_variant 0.95 0
19:45364926:T P169H missense_variant 0.95 0
19:45364926:A P169L missense_variant 0.95 0
19:45364926:C P169R missense_variant 0.95 0
19:45365130:C V130G missense_variant 0.95 0
19:45365119:G C134R missense_variant 0.95 0
19:45365130:T V130D missense_variant 0.95 0
19:45365119:C C134G missense_variant 0.95 0
19:45365119:T C134S missense_variant 0.95 0
19:45365130:G V130A missense_variant 0.95 0
19:45364480:T V221E missense_variant 0.94 0
19:45364480:C V221G missense_variant 0.94 0
19:45364480:G V221A missense_variant 0.94 0
19:45368944:T P78T missense_variant 0.94 0
19:45368943:A P78L missense_variant 0.94 0
19:45368943:C P78R missense_variant 0.94 0
19:45368943:T P78Q missense_variant 0.94 0
19:45368944:C P78A missense_variant 0.94 0
19:45368944:A P78S missense_variant 0.94 0
19:45368967:T L70H missense_variant 0.94 0
19:45368967:C L70R missense_variant 0.94 0
19:45368964:T I71N missense_variant 0.94 0
19:45368964:G I71T missense_variant 0.94 0
19:45368964:C I71S missense_variant 0.94 0
19:45361641:C F374V missense_variant 0.94 0
19:45361641:G F374L missense_variant 0.94 0
19:45361641:T F374I missense_variant 0.94 0
19:45352349:C F684V missense_variant 0.94 0
19:45352349:G F684L missense_variant 0.94 0
19:45368976:T V67E missense_variant 0.94 0
19:45368976:G V67A missense_variant 0.94 0
19:45368976:C V67G missense_variant 0.94 0
19:45352349:T F684I missense_variant 0.94 0
19:45368967:G L70P missense_variant 0.94 0
19:45351696:G L739P missense_variant 0.94 0
19:45351711:T L734Q missense_variant 0.94 0
19:45351711:C L734R missense_variant 0.94 0
19:45364051:A A295V missense_variant 0.94 0
19:45364051:C A295G missense_variant 0.94 0
19:45364051:T A295D missense_variant 0.94 0
19:45351705:T L736Q missense_variant 0.94 0
19:45351705:G L736P missense_variant 0.94 0
19:45351705:C L736R missense_variant 0.94 0
19:45357642:T I432N missense_variant 0.94 0
19:45351703:T S737T missense_variant 0.94 0
19:45351703:G S737P missense_variant 0.94 0
19:45351703:C S737A missense_variant 0.94 0
19:45357642:G I432T missense_variant 0.94 0
19:45357642:C I432S missense_variant 0.94 0
19:45351681:G L744P missense_variant 0.94 0
19:45357634:T F435I missense_variant 0.94 0
19:45351699:T L738Q missense_variant 0.94 0
19:45351699:G L738P missense_variant 0.94 0
19:45351699:C L738R missense_variant 0.94 0
19:45351696:T L739H missense_variant 0.94 0
19:45351711:G L734P missense_variant 0.94 0
19:45357634:G F435L missense_variant 0.94 0
19:45357634:C F435V missense_variant 0.94 0
19:45357633:T F435Y missense_variant 0.94 0
19:45357633:G F435S missense_variant 0.94 0
19:45357633:C F435C missense_variant 0.94 0
19:45351696:C L739R missense_variant 0.94 0
19:45351681:T L744Q missense_variant 0.94 0
19:45351681:C L744R missense_variant 0.94 0
19:45368737:G E85Q missense_variant 0.94 0
19:45368737:T E85K missense_variant 0.94 0
19:45364298:T L251H missense_variant 0.93 0
19:45364298:G L251P missense_variant 0.93 0
19:45364298:C L251R missense_variant 0.93 0
19:45368742:G V83A missense_variant 0.93 0
19:45368742:C V83G missense_variant 0.93 0
19:45368742:T V83E missense_variant 0.93 0
19:45364456:A A229V missense_variant 0.93 0
19:45364456:C A229G missense_variant 0.93 0
19:45364456:T A229D missense_variant 0.93 0
19:45364954:T E160K missense_variant 0.92 0
19:45364954:G E160Q missense_variant 0.92 0
19:45364468:T L225Q missense_variant 0.92 0
19:45364468:C L225R missense_variant 0.92 0
19:45364447:G V232A missense_variant 0.92 0
19:45364468:G L225P missense_variant 0.92 0
19:45364447:T V232D missense_variant 0.92 0
19:45364447:C V232G missense_variant 0.92 0
19:45368734:A E86* stop_gained 0.92 0
19:45364439:G E235Q missense_variant 0.92 0
19:45364439:T E235K missense_variant 0.92 0
19:45364444:T F233Y missense_variant 0.92 0
19:45364444:C F233C missense_variant 0.92 0
19:45364444:G F233S missense_variant 0.92 0
19:45357304:T T482N missense_variant 0.92 0
19:45352592:C F654V missense_variant 0.92 0
19:45352592:G F654L missense_variant 0.92 0
19:45352592:T F654I missense_variant 0.92 0
19:45357347:T P468T missense_variant 0.92 0
19:45357347:C P468A missense_variant 0.92 0
19:45357347:A P468S missense_variant 0.92 0
19:45357346:T P468H missense_variant 0.92 0
19:45357346:C P468R missense_variant 0.92 0
19:45357346:A P468L missense_variant 0.92 0
19:45357329:T H474N missense_variant 0.92 0
19:45357329:C H474D missense_variant 0.92 0
19:45357329:A H474Y missense_variant 0.92 0
19:45357326:T P475T missense_variant 0.92 0
19:45357326:C P475A missense_variant 0.92 0
19:45357326:A P475S missense_variant 0.92 0
19:45357325:T P475H missense_variant 0.92 0
19:45357325:C P475R missense_variant 0.92 0
19:45357325:A P475L missense_variant 0.92 0
19:45357319:T T477N missense_variant 0.92 0
19:45357319:C T477S missense_variant 0.92 0
19:45357319:A T477I missense_variant 0.92 0
19:45357313:T A479E missense_variant 0.92 0
19:45357313:C A479G missense_variant 0.92 0
19:45357313:A A479V missense_variant 0.92 0
19:45357310:T T480N missense_variant 0.92 0
19:45357310:C T480S missense_variant 0.92 0
19:45357310:A T480I missense_variant 0.92 0
19:45357304:C T482S missense_variant 0.92 0
19:45357304:A T482I missense_variant 0.92 0
19:45357292:T A486E missense_variant 0.92 0
19:45357292:C A486G missense_variant 0.92 0
19:45357292:A A486V missense_variant 0.92 0
19:45357274:T P492H missense_variant 0.92 0
19:45357274:C P492R missense_variant 0.92 0
19:45357274:A P492L missense_variant 0.92 0
19:45352519:T V678D missense_variant 0.91 0
19:45352519:G V678A missense_variant 0.91 0
19:45352519:C V678G missense_variant 0.91 0
19:45352561:G V664A missense_variant 0.91 0
19:45352561:T V664E missense_variant 0.91 0
19:45352561:C V664G missense_variant 0.91 0
19:45368949:T T76N missense_variant 0.91 0
19:45368949:A T76I missense_variant 0.91 0
19:45368949:C T76S missense_variant 0.91 0
19:45352241:G F720L missense_variant 0.91 0
19:45352241:C F720V missense_variant 0.91 0
19:45352228:C M724R missense_variant 0.91 0
19:45352228:G M724T missense_variant 0.91 0
19:45352228:T M724K missense_variant 0.91 0
19:45352237:C L721R missense_variant 0.91 0
19:45352237:G L721P missense_variant 0.91 0
19:45352237:T L721Q missense_variant 0.91 0
19:45352240:C F720C missense_variant 0.91 0
19:45352216:T F728Y missense_variant 0.91 0
19:45352217:C F728V missense_variant 0.91 0
19:45352282:T L706H missense_variant 0.91 0
19:45352276:G L708P missense_variant 0.91 0
19:45352276:T L708Q missense_variant 0.91 0
19:45352282:C L706R missense_variant 0.91 0
19:45352240:T F720Y missense_variant 0.91 0
19:45352240:G F720S missense_variant 0.91 0
19:45352216:C F728C missense_variant 0.91 0
19:45352216:G F728S missense_variant 0.91 0
19:45352241:T F720I missense_variant 0.91 0
19:45352297:G L701P missense_variant 0.91 0
19:45352297:C L701R missense_variant 0.91 0
19:45352282:G L706P missense_variant 0.91 0
19:45352258:C V714G missense_variant 0.91 0
19:45352258:G V714A missense_variant 0.91 0
19:45352258:T V714D missense_variant 0.91 0
19:45352217:G F728L missense_variant 0.91 0
19:45352270:C V710G missense_variant 0.91 0
19:45352270:G V710A missense_variant 0.91 0
19:45352321:T L693Q missense_variant 0.91 0
19:45352321:G L693P missense_variant 0.91 0
19:45352321:C L693R missense_variant 0.91 0
19:45352270:T V710E missense_variant 0.91 0
19:45352313:T W696R missense_variant 0.91 0
19:45352313:G W696R missense_variant 0.91 0
19:45352313:C W696G missense_variant 0.91 0
19:45352309:T I697N missense_variant 0.91 0
19:45352309:G I697T missense_variant 0.91 0
19:45352309:C I697S missense_variant 0.91 0
19:45352217:T F728I missense_variant 0.91 0
19:45352276:C L708R missense_variant 0.91 0
19:45352297:T L701H missense_variant 0.91 0
19:45364541:A H201Y missense_variant 0.91 0
19:45364541:C H201D missense_variant 0.91 0
19:45364541:T H201N missense_variant 0.91 0
19:45369144:T H37N missense_variant 0.91 0
19:45369107:A T49I missense_variant 0.91 0
19:45369107:C T49R missense_variant 0.91 0
19:45369107:T T49K missense_variant 0.91 0
19:45369116:A T46I missense_variant 0.91 0
19:45369116:C T46S missense_variant 0.91 0
19:45369116:T T46N missense_variant 0.91 0
19:45369144:A H37Y missense_variant 0.91 0
19:45369144:C H37D missense_variant 0.91 0
19:45368638:T H118N missense_variant 0.91 0
19:45368638:C H118D missense_variant 0.91 0
19:45368658:T S111Y missense_variant 0.91 0
19:45368658:C S111C missense_variant 0.91 0
19:45368658:A S111F missense_variant 0.91 0
19:45364861:A P191S missense_variant 0.91 0
19:45364861:C P191A missense_variant 0.91 0
19:45364861:T P191T missense_variant 0.91 0
19:45368635:T P119T missense_variant 0.91 0
19:45368667:A A108V missense_variant 0.91 0
19:45368667:C A108G missense_variant 0.91 0
19:45364489:C A218G missense_variant 0.91 0
19:45364489:T A218E missense_variant 0.91 0
19:45364514:A H210Y missense_variant 0.91 0
19:45364514:C H210D missense_variant 0.91 0
19:45368667:T A108D missense_variant 0.91 0
19:45368635:C P119A missense_variant 0.91 0
19:45368635:A P119S missense_variant 0.91 0
19:45368634:T P119H missense_variant 0.91 0
19:45368634:C P119R missense_variant 0.91 0
19:45368634:A P119L missense_variant 0.91 0
19:45364514:T H210N missense_variant 0.91 0
19:45364489:A A218V missense_variant 0.91 0
19:45364477:C S222C missense_variant 0.91 0
19:45364477:T S222Y missense_variant 0.91 0
19:45364477:A S222F missense_variant 0.91 0
19:45364295:T T252N missense_variant 0.91 0
19:45364295:A T252I missense_variant 0.91 0
19:45364295:C T252S missense_variant 0.91 0
19:45368947:T V77M missense_variant 0.91 0
19:45368947:A V77L missense_variant 0.91 0
19:45368947:G V77L missense_variant 0.91 0
19:45368958:T C73Y missense_variant 0.91 0
19:45368958:G C73S missense_variant 0.91 0
19:45368958:A C73F missense_variant 0.91 0
19:45369075:C Q60E missense_variant 0.90 0
19:45369075:T Q60K missense_variant 0.90 0
19:45364900:T D178N missense_variant 0.90 0
19:45364900:A D178Y missense_variant 0.90 0
19:45364900:G D178H missense_variant 0.90 0
19:45354803:G V531A missense_variant 0.90 0
19:45354803:T V531D missense_variant 0.90 0
19:45354803:C V531G missense_variant 0.90 0
19:45370156:A L28F missense_variant 0.90 0
19:45370183:A P19S missense_variant 0.90 0
19:45370146:T T31K missense_variant 0.90 0
19:45370146:C T31R missense_variant 0.90 0
19:45370146:A T31M missense_variant 0.90 0
19:45370182:C P19R missense_variant 0.90 0
19:45370170:T S23Y missense_variant 0.90 0
19:45370170:A S23F missense_variant 0.90 0
19:45370182:T P19H missense_variant 0.90 0
19:45370156:T L28I missense_variant 0.90 0
19:45370156:C L28V missense_variant 0.90 0
19:45370183:C P19A missense_variant 0.90 0
19:45370183:T P19T missense_variant 0.90 0
19:45370182:A P19L missense_variant 0.90 0
19:45368733:C E86G missense_variant 0.89 0
19:45368724:G K89T missense_variant 0.89 0
19:45368736:C E85G missense_variant 0.89 0
19:45368736:A E85V missense_variant 0.89 0
19:45368733:G E86A missense_variant 0.89 0
19:45368724:A K89M missense_variant 0.89 0
19:45368724:C K89R missense_variant 0.89 0
19:45368736:G E85A missense_variant 0.89 0
19:45368725:C K89E missense_variant 0.89 0
19:45368725:G K89Q missense_variant 0.89 0
19:45368733:A E86V missense_variant 0.89 0
19:45357358:C L464R missense_variant 0.89 0
19:45357367:T L461Q missense_variant 0.89 0
19:45357367:G L461P missense_variant 0.89 0
19:45357367:C L461R missense_variant 0.89 0
19:45357365:T S462T missense_variant 0.89 0
19:45357365:G S462P missense_variant 0.89 0
19:45357365:C S462A missense_variant 0.89 0
19:45357358:T L464Q missense_variant 0.89 0
19:45357358:G L464P missense_variant 0.89 0
19:45363842:T V340E missense_variant 0.89 0
19:45363842:G V340A missense_variant 0.89 0
19:45369128:C M42R missense_variant 0.89 0
19:45369128:G M42T missense_variant 0.89 0
19:45363842:C V340G missense_variant 0.89 0
19:45369128:T M42K missense_variant 0.89 0
19:45364117:G I273T missense_variant 0.88 0
19:45364117:C I273S missense_variant 0.88 0
19:45364117:T I273N missense_variant 0.88 0
19:45354806:G V530A missense_variant 0.88 0
19:45354806:C V530G missense_variant 0.88 0
19:45354806:T V530E missense_variant 0.88 0
19:45353250:G Y584H missense_variant 0.88 0
19:45353250:C Y584D missense_variant 0.88 0
19:45353250:T Y584N missense_variant 0.88 0
19:45352798:A A617V missense_variant 0.87 0
19:45352798:C A617G missense_variant 0.87 0
19:45352798:T A617D missense_variant 0.87 0
19:45352777:A P624L missense_variant 0.87 0
19:45352777:C P624R missense_variant 0.87 0
19:45352777:T P624H missense_variant 0.87 0
19:45352778:A P624S missense_variant 0.87 0
19:45352778:C P624A missense_variant 0.87 0
19:45352778:T P624T missense_variant 0.87 0
19:45357478:C S458C missense_variant 0.87 0
19:45355691:T S506Y missense_variant 0.87 0
19:45355691:C S506C missense_variant 0.87 0
19:45355691:A S506F missense_variant 0.87 0
19:45357478:T S458Y missense_variant 0.87 0
19:45357481:A T457I missense_variant 0.87 0
19:45357481:C T457R missense_variant 0.87 0
19:45357481:T T457K missense_variant 0.87 0
19:45357478:A S458F missense_variant 0.87 0
19:45355707:T Q501K missense_variant 0.87 0
19:45355707:C Q501E missense_variant 0.87 0
19:45355700:T A503D missense_variant 0.87 0
19:45355700:C A503G missense_variant 0.87 0
19:45355700:A A503V missense_variant 0.87 0
19:45357523:T A443D missense_variant 0.87 0
19:45357497:C Q452E missense_variant 0.87 0
19:45357497:T Q452K missense_variant 0.87 0
19:45357514:A P446L missense_variant 0.87 0
19:45357514:C P446R missense_variant 0.87 0
19:45357514:T P446H missense_variant 0.87 0
19:45357523:C A443G missense_variant 0.87 0
19:45357529:A S441L missense_variant 0.87 0
19:45357529:C S441W missense_variant 0.87 0
19:45352816:G V611A missense_variant 0.86 0
19:45352771:C V626G missense_variant 0.86 0
19:45352816:T V611E missense_variant 0.86 0
19:45352771:G V626A missense_variant 0.86 0
19:45352771:T V626D missense_variant 0.86 0
19:45352816:C V611G missense_variant 0.86 0
19:45357301:C M483R missense_variant 0.85 0
19:45357301:G M483T missense_variant 0.85 0
19:45357301:T M483K missense_variant 0.85 0
19:45357307:T F481Y missense_variant 0.85 0
19:45357307:G F481S missense_variant 0.85 0
19:45357307:C F481C missense_variant 0.85 0
19:45357352:C I466S missense_variant 0.85 0
19:45357350:T Y467N missense_variant 0.85 0
19:45357350:G Y467H missense_variant 0.85 0
19:45357340:G I470T missense_variant 0.85 0
19:45357340:C I470S missense_variant 0.85 0
19:45357337:T L471Q missense_variant 0.85 0
19:45357337:G L471P missense_variant 0.85 0
19:45357337:C L471R missense_variant 0.85 0
19:45357332:T F473I missense_variant 0.85 0
19:45357332:G F473L missense_variant 0.85 0
19:45357332:C F473V missense_variant 0.85 0
19:45357352:G I466T missense_variant 0.85 0
19:45357350:C Y467D missense_variant 0.85 0
19:45357340:T I470N missense_variant 0.85 0
19:45357352:T I466N missense_variant 0.85 0
19:45357331:T F473Y missense_variant 0.85 0
19:45357331:G F473S missense_variant 0.85 0
19:45357331:C F473C missense_variant 0.85 0
19:45357322:T V476D missense_variant 0.85 0
19:45357284:C C489G missense_variant 0.85 0
19:45357284:G C489R missense_variant 0.85 0
19:45357284:T C489S missense_variant 0.85 0
19:45357322:G V476A missense_variant 0.85 0
19:45357322:C V476G missense_variant 0.85 0
19:45357295:C L485R missense_variant 0.85 0
19:45357295:G L485P missense_variant 0.85 0
19:45357316:T M478K missense_variant 0.85 0
19:45357295:T L485Q missense_variant 0.85 0
19:45357316:G M478T missense_variant 0.85 0
19:45357316:C M478R missense_variant 0.85 0
19:45357308:T F481I missense_variant 0.85 0
19:45357308:G F481L missense_variant 0.85 0
19:45357308:C F481V missense_variant 0.85 0
19:45369086:C I56S missense_variant 0.85 0
19:45369134:T L40Q missense_variant 0.85 0
19:45369134:G L40P missense_variant 0.85 0
19:45369134:C L40R missense_variant 0.85 0
19:45369102:T S51T missense_variant 0.85 0
19:45369102:G S51P missense_variant 0.85 0
19:45369102:C S51A missense_variant 0.85 0
19:45369098:T L52Q missense_variant 0.85 0
19:45369098:G L52P missense_variant 0.85 0
19:45369098:C L52R missense_variant 0.85 0
19:45369086:T I56N missense_variant 0.85 0
19:45369086:G I56T missense_variant 0.85 0
19:45351640:T Q758K missense_variant 0.85 0
19:45351642:A A757V missense_variant 0.85 0
19:45351642:C A757G missense_variant 0.85 0
19:45351642:T A757D missense_variant 0.85 0
19:45368930:G K82N missense_variant 0.84 0
19:45368930:A K82N missense_variant 0.84 0
19:45353130:G I595T missense_variant 0.84 0
19:45353103:G V604A missense_variant 0.84 0
19:45353103:C V604G missense_variant 0.84 0
19:45353130:C I595S missense_variant 0.84 0
19:45353103:T V604E missense_variant 0.84 0
19:45353130:T I595N missense_variant 0.84 0
19:45368637:G H118P missense_variant 0.84 0
19:45368631:C E120G missense_variant 0.84 0
19:45368631:A E120V missense_variant 0.84 0
19:45368649:G N114T missense_variant 0.84 0
19:45368649:C N114S missense_variant 0.84 0
19:45368649:A N114I missense_variant 0.84 0
19:45368637:C H118R missense_variant 0.84 0
19:45368650:A N114Y missense_variant 0.84 0
19:45368650:C N114D missense_variant 0.84 0
19:45368650:G N114H missense_variant 0.84 0
19:45368637:A H118L missense_variant 0.84 0
19:45368631:G E120A missense_variant 0.84 0
19:45364872:A Q187L missense_variant 0.84 0
19:45364872:G Q187P missense_variant 0.84 0
19:45364872:C Q187R missense_variant 0.84 0
19:45357490:T V454D missense_variant 0.84 0
19:45357490:G V454A missense_variant 0.84 0
19:45357490:C V454G missense_variant 0.84 0
19:45357542:C C437G missense_variant 0.84 0
19:45357542:G C437R missense_variant 0.84 0
19:45357542:T C437S missense_variant 0.84 0
19:45357500:G F451L missense_variant 0.84 0
19:45357500:T F451I missense_variant 0.84 0
19:45357530:C S441A missense_variant 0.84 0
19:45357530:G S441P missense_variant 0.84 0
19:45357499:T F451Y missense_variant 0.84 0
19:45357499:C F451C missense_variant 0.84 0
19:45357499:G F451S missense_variant 0.84 0
19:45357500:C F451V missense_variant 0.84 0
19:45357530:T S441T missense_variant 0.84 0
19:45365136:A K128M missense_variant 0.84 0
19:45365127:G D131A missense_variant 0.84 0
19:45365127:C D131G missense_variant 0.84 0
19:45365127:A D131V missense_variant 0.84 0
19:45365133:A D129V missense_variant 0.84 0
19:45365133:C D129G missense_variant 0.84 0
19:45365133:G D129A missense_variant 0.84 0
19:45365137:G K128Q missense_variant 0.84 0
19:45365137:C K128E missense_variant 0.84 0
19:45365136:G K128T missense_variant 0.84 0
19:45365136:C K128R missense_variant 0.84 0
19:45351663:G L750P missense_variant 0.84 0
19:45351645:C I756S missense_variant 0.84 0
19:45351645:G I756T missense_variant 0.84 0
19:45351645:T I756N missense_variant 0.84 0
19:45351663:T L750Q missense_variant 0.84 0
19:45351663:C L750R missense_variant 0.84 0
19:45351654:T I753K missense_variant 0.84 0
19:45351654:G I753T missense_variant 0.84 0
19:45351654:C I753R missense_variant 0.84 0
19:45354780:C F539V missense_variant 0.83 0
19:45354771:T Y542N missense_variant 0.83 0
19:45354771:G Y542H missense_variant 0.83 0
19:45354779:G F539S missense_variant 0.83 0
19:45364256:T T265N missense_variant 0.83 0
19:45364256:C T265S missense_variant 0.83 0
19:45364256:A T265I missense_variant 0.83 0
19:45354779:C F539C missense_variant 0.83 0
19:45354741:C W552G missense_variant 0.83 0
19:45354782:T F538Y missense_variant 0.83 0
19:45354782:G F538S missense_variant 0.83 0
19:45354782:C F538C missense_variant 0.83 0
19:45354780:T F539I missense_variant 0.83 0
19:45354780:G F539L missense_variant 0.83 0
19:45354779:T F539Y missense_variant 0.83 0
19:45354741:T W552R missense_variant 0.83 0
19:45354741:G W552R missense_variant 0.83 0
19:45354738:T Y553N missense_variant 0.83 0
19:45354771:C Y542D missense_variant 0.83 0
19:45354761:T M545K missense_variant 0.83 0
19:45354761:G M545T missense_variant 0.83 0
19:45354761:C M545R missense_variant 0.83 0
19:45354738:G Y553H missense_variant 0.83 0
19:45354738:C Y553D missense_variant 0.83 0
19:45363879:C H328D missense_variant 0.83 0
19:45363879:T H328N missense_variant 0.83 0
19:45363879:A H328Y missense_variant 0.83 0
19:45364430:A N238Y missense_variant 0.83 0
19:45364430:C N238D missense_variant 0.83 0
19:45364430:G N238H missense_variant 0.83 0
19:45363797:T P355H missense_variant 0.83 0
19:45363797:C P355R missense_variant 0.83 0
19:45363797:A P355L missense_variant 0.83 0
19:45364060:C L292R missense_variant 0.83 0
19:45364060:T L292Q missense_variant 0.83 0
19:45364060:G L292P missense_variant 0.83 0
19:45353085:G F610S missense_variant 0.83 0
19:45353085:T F610Y missense_variant 0.83 0
19:45353085:C F610C missense_variant 0.83 0
19:45365092:A R143W missense_variant 0.82 0
19:45365106:C T138R missense_variant 0.82 0
19:45365106:A T138I missense_variant 0.82 0
19:45365106:T T138K missense_variant 0.82 0
19:45365092:C R143G missense_variant 0.82 0
19:45353318:C I561S missense_variant 0.82 0
19:45353294:C I569S missense_variant 0.82 0
19:45353258:T L581Q missense_variant 0.82 0
19:45353327:T L558H missense_variant 0.82 0
19:45353330:C I557S missense_variant 0.82 0
19:45353294:G I569T missense_variant 0.82 0
19:45353294:T I569N missense_variant 0.82 0
19:45353297:C F568C missense_variant 0.82 0
19:45353297:G F568S missense_variant 0.82 0
19:45353297:T F568Y missense_variant 0.82 0
19:45353298:C F568V missense_variant 0.82 0
19:45353298:G F568L missense_variant 0.82 0
19:45353298:T F568I missense_variant 0.82 0
19:45353300:C L567R missense_variant 0.82 0
19:45353300:G L567P missense_variant 0.82 0
19:45353300:T L567H missense_variant 0.82 0
19:45353303:C L566R missense_variant 0.82 0
19:45353303:G L566P missense_variant 0.82 0
19:45353303:T L566Q missense_variant 0.82 0
19:45353264:G V579A missense_variant 0.82 0
19:45353330:G I557T missense_variant 0.82 0
19:45353330:T I557N missense_variant 0.82 0
19:45353258:G L581P missense_variant 0.82 0
19:45353327:G L558P missense_variant 0.82 0
19:45353264:C V579G missense_variant 0.82 0
19:45353258:C L581R missense_variant 0.82 0
19:45353318:G I561T missense_variant 0.82 0
19:45353264:T V579D missense_variant 0.82 0
19:45353327:C L558R missense_variant 0.82 0
19:45353318:T I561N missense_variant 0.82 0
19:45364082:T Y285N missense_variant 0.82 0
19:45364082:G Y285H missense_variant 0.82 0
19:45364082:C Y285D missense_variant 0.82 0
19:45352811:A H613Y missense_variant 0.82 0
19:45352814:T H612N missense_variant 0.82 0
19:45352811:C H613D missense_variant 0.82 0
19:45352814:A H612Y missense_variant 0.82 0
19:45352814:C H612D missense_variant 0.82 0
19:45352811:T H613N missense_variant 0.82 0
19:45368985:T P64Q missense_variant 0.82 0
19:45364072:G L288P missense_variant 0.82 0
19:45364072:C L288R missense_variant 0.82 0
19:45368986:C P64A missense_variant 0.82 0
19:45364072:T L288Q missense_variant 0.82 0
19:45368985:A P64L missense_variant 0.82 0
19:45368986:A P64S missense_variant 0.82 0
19:45368986:T P64T missense_variant 0.82 0
19:45368985:C P64R missense_variant 0.82 0
19:45363792:T F357I missense_variant 0.82 0
19:45363792:G F357L missense_variant 0.82 0
19:45363792:C F357V missense_variant 0.82 0
19:45351685:C Q743E missense_variant 0.82 0
19:45351675:A S746L missense_variant 0.82 0
19:45357645:A P431L missense_variant 0.82 0
19:45357645:C P431R missense_variant 0.82 0
19:45357645:T P431H missense_variant 0.82 0
19:45357646:A P431S missense_variant 0.82 0
19:45357646:C P431A missense_variant 0.82 0
19:45357646:T P431T missense_variant 0.82 0
19:45351702:A S737F missense_variant 0.82 0
19:45351702:C S737C missense_variant 0.82 0
19:45351702:T S737Y missense_variant 0.82 0
19:45351685:T Q743K missense_variant 0.82 0
19:45351715:T Q733K missense_variant 0.82 0
19:45351715:C Q733E missense_variant 0.82 0
19:45357637:C H434D missense_variant 0.82 0
19:45357660:C P426R missense_variant 0.82 0
19:45357660:A P426L missense_variant 0.82 0
19:45357679:T P420T missense_variant 0.82 0
19:45357637:A H434Y missense_variant 0.82 0
19:45357679:C P420A missense_variant 0.82 0
19:45357679:A P420S missense_variant 0.82 0
19:45357637:T H434N missense_variant 0.82 0
19:45357660:T P426Q missense_variant 0.82 0
19:45352318:T P694H missense_variant 0.81 0
19:45353261:T A580D missense_variant 0.81 0
19:45353261:C A580G missense_variant 0.81 0
19:45353261:A A580V missense_variant 0.81 0
19:45354732:T Q555K missense_variant 0.81 0
19:45354732:C Q555E missense_variant 0.81 0
19:45353270:T T577N missense_variant 0.81 0
19:45353276:A A575V missense_variant 0.81 0
19:45353276:C A575G missense_variant 0.81 0
19:45354851:T A515D missense_variant 0.81 0
19:45354851:C A515G missense_variant 0.81 0
19:45354851:A A515V missense_variant 0.81 0
19:45353276:T A575D missense_variant 0.81 0
19:45353286:C Q572E missense_variant 0.81 0
19:45353286:T Q572K missense_variant 0.81 0
19:45353288:A T571I missense_variant 0.81 0
19:45353288:C T571S missense_variant 0.81 0
19:45353288:T T571N missense_variant 0.81 0
19:45364108:T T276K missense_variant 0.81 0
19:45364108:A T276I missense_variant 0.81 0
19:45364108:C T276R missense_variant 0.81 0
19:45353100:T S605Y missense_variant 0.81 0
19:45353100:C S605C missense_variant 0.81 0
19:45353100:A S605F missense_variant 0.81 0
19:45353316:C Q562E missense_variant 0.81 0
19:45353316:T Q562K missense_variant 0.81 0
19:45354812:T S528Y missense_variant 0.81 0
19:45354812:C S528C missense_variant 0.81 0
19:45361535:A T409I missense_variant 0.81 0
19:45361535:C T409S missense_variant 0.81 0
19:45361535:T T409N missense_variant 0.81 0
19:45352625:T Q643K missense_variant 0.81 0
19:45361547:A T405I missense_variant 0.81 0
19:45361547:C T405S missense_variant 0.81 0
19:45361547:T T405N missense_variant 0.81 0
19:45352625:C Q643E missense_variant 0.81 0
19:45354812:A S528F missense_variant 0.81 0
19:45354801:T P532T missense_variant 0.81 0
19:45352594:T T653N missense_variant 0.81 0
19:45352594:C T653S missense_variant 0.81 0
19:45352594:A T653I missense_variant 0.81 0
19:45352585:T A656D missense_variant 0.81 0
19:45352585:C A656G missense_variant 0.81 0
19:45352585:A A656V missense_variant 0.81 0
19:45361566:A L399F missense_variant 0.81 0
19:45361566:C L399V missense_variant 0.81 0
19:45361566:T L399I missense_variant 0.81 0
19:45352573:T A660E missense_variant 0.81 0
19:45352573:C A660G missense_variant 0.81 0
19:45352573:A A660V missense_variant 0.81 0
19:45352568:T Q662K missense_variant 0.81 0
19:45352568:C Q662E missense_variant 0.81 0
19:45361574:A P396L missense_variant 0.81 0
19:45361574:C P396R missense_variant 0.81 0
19:45361574:T P396Q missense_variant 0.81 0
19:45361577:A S395F missense_variant 0.81 0
19:45361577:C S395C missense_variant 0.81 0
19:45361577:T S395Y missense_variant 0.81 0
19:45361586:A A392V missense_variant 0.81 0
19:45361586:C A392G missense_variant 0.81 0
19:45361586:T A392D missense_variant 0.81 0
19:45354801:C P532A missense_variant 0.81 0
19:45354801:A P532S missense_variant 0.81 0
19:45354746:A A550V missense_variant 0.81 0
19:45354746:C A550G missense_variant 0.81 0
19:45354746:T A550D missense_variant 0.81 0
19:45352319:T P694T missense_variant 0.81 0
19:45352319:C P694A missense_variant 0.81 0
19:45352319:A P694S missense_variant 0.81 0
19:45361607:A T385I missense_variant 0.81 0
19:45361607:C T385S missense_variant 0.81 0
19:45361607:T T385N missense_variant 0.81 0
19:45352318:C P694R missense_variant 0.81 0
19:45352318:A P694L missense_variant 0.81 0
19:45352316:T R695S missense_variant 0.81 0
19:45352316:C R695G missense_variant 0.81 0
19:45352316:A R695C missense_variant 0.81 0
19:45352307:T Q698K missense_variant 0.81 0
19:45352307:C Q698E missense_variant 0.81 0
19:45352301:T H700N missense_variant 0.81 0
19:45352301:C H700D missense_variant 0.81 0
19:45352301:A H700Y missense_variant 0.81 0
19:45352273:T T709N missense_variant 0.81 0
19:45352273:C T709S missense_variant 0.81 0
19:45352273:A T709I missense_variant 0.81 0
19:45352256:T Q715K missense_variant 0.81 0
19:45352256:C Q715E missense_variant 0.81 0
19:45352249:T A717D missense_variant 0.81 0
19:45352249:C A717G missense_variant 0.81 0
19:45361634:A A376V missense_variant 0.81 0
19:45361634:C A376G missense_variant 0.81 0
19:45361634:T A376D missense_variant 0.81 0
19:45352249:A A717V missense_variant 0.81 0
19:45352225:T A725E missense_variant 0.81 0
19:45352225:C A725G missense_variant 0.81 0
19:45352225:A A725V missense_variant 0.81 0
19:45352223:T Q726K missense_variant 0.81 0
19:45352223:C Q726E missense_variant 0.81 0
19:45352220:T P727T missense_variant 0.81 0
19:45352220:C P727A missense_variant 0.81 0
19:45352220:A P727S missense_variant 0.81 0
19:45352219:T P727H missense_variant 0.81 0
19:45352219:C P727R missense_variant 0.81 0
19:45352219:A P727L missense_variant 0.81 0
19:45354776:A T540I missense_variant 0.81 0
19:45364013:A P308S missense_variant 0.81 0
19:45364013:C P308A missense_variant 0.81 0
19:45364013:T P308T missense_variant 0.81 0
19:45354776:T T540N missense_variant 0.81 0
19:45354776:C T540S missense_variant 0.81 0
19:45353270:C T577S missense_variant 0.81 0
19:45353270:A T577I missense_variant 0.81 0
19:45363884:A A326V missense_variant 0.81 0
19:45363884:C A326G missense_variant 0.81 0
19:45363884:T A326D missense_variant 0.81 0
19:45354735:T E554K missense_variant 0.79 0
19:45354730:A Q555H missense_variant 0.79 0
19:45354730:G Q555H missense_variant 0.79 0
19:45354830:C N522S missense_variant 0.79 0
19:45354830:G N522T missense_variant 0.79 0
19:45354830:A N522I missense_variant 0.79 0
19:45353133:A A594V missense_variant 0.79 0
19:45364054:G E294A missense_variant 0.79 0
19:45364054:C E294G missense_variant 0.79 0
19:45364054:A E294V missense_variant 0.79 0
19:45353133:T A594D missense_variant 0.79 0
19:45353133:C A594G missense_variant 0.79 0
19:45364520:G S208R missense_variant 0.79 0
19:45364520:C S208G missense_variant 0.79 0
19:45364520:A S208C missense_variant 0.79 0
19:45357509:G F448L missense_variant 0.78 0
19:45357509:T F448I missense_variant 0.78 0
19:45357511:C V447G missense_variant 0.78 0
19:45357479:C S458A missense_variant 0.78 0
19:45357511:G V447A missense_variant 0.78 0
19:45357508:C F448C missense_variant 0.78 0
19:45357511:T V447E missense_variant 0.78 0
19:45357508:G F448S missense_variant 0.78 0
19:45357479:G S458P missense_variant 0.78 0
19:45357508:T F448Y missense_variant 0.78 0
19:45357509:C F448V missense_variant 0.78 0
19:45357479:T S458T missense_variant 0.78 0
19:45355686:T F508I missense_variant 0.78 0
19:45355692:C S506A missense_variant 0.78 0
19:45355685:C F508C missense_variant 0.78 0
19:45352750:G L633P missense_variant 0.78 0
19:45352750:T L633H missense_variant 0.78 0
19:45352769:C Y627D missense_variant 0.78 0
19:45352769:G Y627H missense_variant 0.78 0
19:45352769:T Y627N missense_variant 0.78 0
19:45355724:C I495S missense_variant 0.78 0
19:45355724:G I495T missense_variant 0.78 0
19:45355724:T I495N missense_variant 0.78 0
19:45355727:C I494S missense_variant 0.78 0
19:45355727:G I494T missense_variant 0.78 0
19:45355727:T I494N missense_variant 0.78 0
19:45355686:C F508V missense_variant 0.78 0
19:45355686:G F508L missense_variant 0.78 0
19:45355703:T V502E missense_variant 0.78 0
19:45355703:G V502A missense_variant 0.78 0
19:45355703:C V502G missense_variant 0.78 0
19:45355685:G F508S missense_variant 0.78 0
19:45355667:C I514S missense_variant 0.78 0
19:45355697:T I504N missense_variant 0.78 0
19:45355667:G I514T missense_variant 0.78 0
19:45355667:T I514N missense_variant 0.78 0
19:45352750:C L633R missense_variant 0.78 0
19:45355697:G I504T missense_variant 0.78 0
19:45355697:C I504S missense_variant 0.78 0
19:45355692:T S506T missense_variant 0.78 0
19:45355692:G S506P missense_variant 0.78 0
19:45355685:T F508Y missense_variant 0.78 0
19:45354788:T V536E missense_variant 0.78 0
19:45354788:G V536A missense_variant 0.78 0
19:45354788:C V536G missense_variant 0.78 0
19:45364066:A E290V missense_variant 0.78 0
19:45364109:G T276P missense_variant 0.78 0
19:45364109:A T276S missense_variant 0.78 0
19:45364109:C T276A missense_variant 0.78 0
19:45364066:C E290G missense_variant 0.78 0
19:45364066:G E290A missense_variant 0.78 0
19:45351643:T A757T missense_variant 0.78 0
19:45351643:A A757S missense_variant 0.78 0
19:45351643:G A757P missense_variant 0.78 0
19:45370188:C I17S missense_variant 0.78 0
19:45370198:G Y14H missense_variant 0.78 0
19:45370198:C Y14D missense_variant 0.78 0
19:45370164:C M25R missense_variant 0.78 0
19:45370198:T Y14N missense_variant 0.78 0
19:45370188:G I17T missense_variant 0.78 0
19:45370164:T M25K missense_variant 0.78 0
19:45370188:T I17N missense_variant 0.78 0
19:45370164:G M25T missense_variant 0.78 0
19:45365151:A P123L missense_variant 0.77 0
19:45365151:C P123R missense_variant 0.77 0
19:45365151:T P123H missense_variant 0.77 0
19:45364004:C P311A missense_variant 0.76 0
19:45364004:T P311T missense_variant 0.76 0
19:45364004:A P311S missense_variant 0.76 0
19:45364305:A V249F missense_variant 0.76 0
19:45364305:G V249L missense_variant 0.76 0
19:45364305:T V249I missense_variant 0.76 0
19:45364486:G D219A missense_variant 0.76 0
19:45364486:C D219G missense_variant 0.76 0
19:45364486:A D219V missense_variant 0.76 0
19:45364031:T D302N missense_variant 0.75 0
19:45364031:A D302Y missense_variant 0.75 0
19:45364031:G D302H missense_variant 0.75 0
19:45364081:G Y285S missense_variant 0.75 0
19:45364081:C Y285C missense_variant 0.75 0
19:45364081:A Y285F missense_variant 0.75 0
19:45368938:A I80F missense_variant 0.75 0
19:45368940:A E79V missense_variant 0.75 0
19:45368938:G I80L missense_variant 0.75 0
19:45368938:C I80V missense_variant 0.75 0
19:45368934:G E81A missense_variant 0.75 0
19:45368934:C E81G missense_variant 0.75 0
19:45368934:A E81V missense_variant 0.75 0
19:45368932:G K82Q missense_variant 0.75 0
19:45368932:C K82E missense_variant 0.75 0
19:45368931:G K82T missense_variant 0.75 0
19:45368931:C K82R missense_variant 0.75 0
19:45368931:A K82M missense_variant 0.75 0
19:45368940:G E79A missense_variant 0.75 0
19:45368940:C E79G missense_variant 0.75 0
19:45364003:T P311H missense_variant 0.75 0
19:45364003:C P311R missense_variant 0.75 0
19:45364003:A P311L missense_variant 0.75 0
19:45354777:C T540A missense_variant 0.75 0
19:45354743:A S551F missense_variant 0.75 0
19:45354743:C S551C missense_variant 0.75 0
19:45354743:T S551Y missense_variant 0.75 0
19:45354777:G T540P missense_variant 0.75 0
19:45354777:A T540S missense_variant 0.75 0
19:45368980:G E66Q missense_variant 0.75 0
19:45368980:T E66K missense_variant 0.75 0
19:45351637:C Q759E missense_variant 0.75 0
19:45351637:T Q759K missense_variant 0.75 0
19:45361559:A A401V missense_variant 0.75 0
19:45361559:C A401G missense_variant 0.75 0
19:45361559:T A401D missense_variant 0.75 0
19:45357496:C Q452R missense_variant 0.75 0
19:45352345:T A685D missense_variant 0.75 0
19:45352345:C A685G missense_variant 0.75 0
19:45357496:G Q452P missense_variant 0.75 0
19:45357518:C K445E missense_variant 0.75 0
19:45357496:A Q452L missense_variant 0.75 0
19:45357518:G K445Q missense_variant 0.75 0
19:45352345:A A685V missense_variant 0.75 0
19:45354789:G V536L missense_variant 0.74 0
19:45354789:T V536M missense_variant 0.74 0
19:45354750:T V549M missense_variant 0.74 0
19:45354759:G E546Q missense_variant 0.74 0
19:45354759:T E546K missense_variant 0.74 0
19:45354794:T G534D missense_variant 0.74 0
19:45354794:G G534A missense_variant 0.74 0
19:45354740:G W552S missense_variant 0.74 0
19:45354740:A W552L missense_variant 0.74 0
19:45354739:G W552C missense_variant 0.74 0
19:45354750:A V549L missense_variant 0.74 0
19:45354750:G V549L missense_variant 0.74 0
19:45354794:A G534V missense_variant 0.74 0
19:45354739:A W552C missense_variant 0.74 0
19:45354789:A V536L missense_variant 0.74 0
19:45363743:A R373I missense_variant 0.74 0
19:45363743:T R373K missense_variant 0.74 0
19:45354822:T L525M missense_variant 0.74 0
19:45354822:C L525V missense_variant 0.74 0
19:45363743:G R373T missense_variant 0.74 0
19:45363888:G T325P missense_variant 0.74 0
19:45354798:A D533Y missense_variant 0.74 0
19:45363888:C T325A missense_variant 0.74 0
19:45354798:G D533H missense_variant 0.74 0
19:45363888:A T325S missense_variant 0.74 0
19:45354798:T D533N missense_variant 0.74 0
19:45368743:G V83L missense_variant 0.74 0
19:45368743:A V83L missense_variant 0.74 0
19:45368743:T V83M missense_variant 0.74 0
19:45364309:T M247I missense_variant 0.73 0
19:45364309:A M247I missense_variant 0.73 0
19:45364309:G M247I missense_variant 0.73 0
19:45364445:C F233V missense_variant 0.73 0
19:45364445:G F233L missense_variant 0.73 0
19:45364445:T F233I missense_variant 0.73 0
19:45364523:C Y207D missense_variant 0.73 0
19:45364523:G Y207H missense_variant 0.73 0
19:45364523:T Y207N missense_variant 0.73 0
19:45370176:C Q21R missense_variant 0.73 0
19:45370140:C D33G missense_variant 0.73 0
19:45370140:G D33A missense_variant 0.73 0
19:45370158:C E27G missense_variant 0.73 0
19:45370158:A E27V missense_variant 0.73 0
19:45370153:G K29Q missense_variant 0.73 0
19:45370153:C K29E missense_variant 0.73 0
19:45370147:G T31P missense_variant 0.73 0
19:45370158:G E27A missense_variant 0.73 0
19:45370147:C T31A missense_variant 0.73 0
19:45370147:A T31S missense_variant 0.73 0
19:45370176:A Q21L missense_variant 0.73 0
19:45370197:G Y14S missense_variant 0.73 0
19:45370140:A D33V missense_variant 0.73 0
19:45370176:G Q21P missense_variant 0.73 0
19:45370197:A Y14F missense_variant 0.73 0
19:45364525:C V206G missense_variant 0.73 0
19:45364525:T V206D missense_variant 0.73 0
19:45364525:G V206A missense_variant 0.73 0
19:45363746:G L372P missense_variant 0.73 0
19:45363746:C L372R missense_variant 0.73 0
19:45363746:T L372H missense_variant 0.73 0
19:45352576:A H659L missense_variant 0.73 0
19:45352576:C H659R missense_variant 0.73 0
19:45352576:G H659P missense_variant 0.73 0
19:45354800:A P532L missense_variant 0.73 0
19:45354800:T P532H missense_variant 0.73 0
19:45354800:C P532R missense_variant 0.73 0
19:45364433:C H237D missense_variant 0.73 0
19:45364433:A H237Y missense_variant 0.73 0
19:45364433:T H237N missense_variant 0.73 0
19:45368727:A R88L missense_variant 0.73 0
19:45368727:T R88Q missense_variant 0.73 0
19:45368727:G R88P missense_variant 0.73 0
19:45368941:T E79K missense_variant 0.72 0
19:45368941:G E79Q missense_variant 0.72 0
19:45364911:C I174S missense_variant 0.72 0
19:45364911:G I174T missense_variant 0.72 0
19:45364911:T I174N missense_variant 0.72 0
19:45364950:C F161C missense_variant 0.72 0
19:45364950:T F161Y missense_variant 0.72 0
19:45364950:G F161S missense_variant 0.72 0
19:45354731:A Q555L missense_variant 0.72 0
19:45354731:C Q555R missense_variant 0.72 0
19:45354731:G Q555P missense_variant 0.72 0
19:45354734:A E554V missense_variant 0.72 0
19:45354734:C E554G missense_variant 0.72 0
19:45354734:G E554A missense_variant 0.72 0
19:45354737:A Y553F missense_variant 0.72 0
19:45354737:C Y553C missense_variant 0.72 0
19:45354737:G Y553S missense_variant 0.72 0
19:45354839:C N519S missense_variant 0.72 0
19:45354839:G N519T missense_variant 0.72 0
19:45363986:G E317Q missense_variant 0.72 0
19:45354840:A N519Y missense_variant 0.72 0
19:45354840:C N519D missense_variant 0.72 0
19:45354840:G N519H missense_variant 0.72 0
19:45363986:T E317K missense_variant 0.72 0
19:45354839:A N519I missense_variant 0.72 0
19:45353282:C D573G missense_variant 0.72 0
19:45353282:G D573A missense_variant 0.72 0
19:45353291:G E570A missense_variant 0.72 0
19:45353306:G K565T missense_variant 0.72 0
19:45353307:C K565E missense_variant 0.72 0
19:45353307:G K565Q missense_variant 0.72 0
19:45353309:A N564I missense_variant 0.72 0
19:45353309:C N564S missense_variant 0.72 0
19:45353309:G N564T missense_variant 0.72 0
19:45353310:A N564Y missense_variant 0.72 0
19:45353310:C N564D missense_variant 0.72 0
19:45353310:G N564H missense_variant 0.72 0
19:45353315:A Q562L missense_variant 0.72 0
19:45353315:C Q562R missense_variant 0.72 0
19:45353315:G Q562P missense_variant 0.72 0
19:45353322:A N560Y missense_variant 0.72 0
19:45353322:C N560D missense_variant 0.72 0
19:45353322:G N560H missense_variant 0.72 0
19:45353324:A E559V missense_variant 0.72 0
19:45353324:C E559G missense_variant 0.72 0
19:45353324:G E559A missense_variant 0.72 0
19:45353331:A I557F missense_variant 0.72 0
19:45353331:C I557V missense_variant 0.72 0
19:45353331:G I557L missense_variant 0.72 0
19:45353291:C E570G missense_variant 0.72 0
19:45353291:A E570V missense_variant 0.72 0
19:45353306:C K565R missense_variant 0.72 0
19:45353306:A K565M missense_variant 0.72 0
19:45353295:G I569L missense_variant 0.72 0
19:45353295:C I569V missense_variant 0.72 0
19:45353295:A I569F missense_variant 0.72 0
19:45353289:G T571P missense_variant 0.72 0
19:45353289:C T571A missense_variant 0.72 0
19:45353289:A T571S missense_variant 0.72 0
19:45353268:A S578C missense_variant 0.72 0
19:45353268:C S578G missense_variant 0.72 0
19:45353268:G S578R missense_variant 0.72 0
19:45353271:A T577S missense_variant 0.72 0
19:45353271:C T577A missense_variant 0.72 0
19:45353271:G T577P missense_variant 0.72 0
19:45353273:A E576V missense_variant 0.72 0
19:45353273:C E576G missense_variant 0.72 0
19:45353273:G E576A missense_variant 0.72 0
19:45353282:A D573V missense_variant 0.72 0
19:45364320:A I244F missense_variant 0.71 0
19:45364328:C N241S missense_variant 0.71 0
19:45364328:G N241T missense_variant 0.71 0
19:45364328:A N241I missense_variant 0.71 0
19:45365048:C F157L missense_variant 0.71 0
19:45365048:T F157L missense_variant 0.71 0
19:45364316:G D245A missense_variant 0.71 0
19:45364316:C D245G missense_variant 0.71 0
19:45364320:G I244L missense_variant 0.71 0
19:45364316:A D245V missense_variant 0.71 0
19:45364320:C I244V missense_variant 0.71 0
19:45364839:A S198L missense_variant 0.71 0
19:45369122:T S44* stop_gained 0.71 0
19:45369122:C S44* stop_gained 0.71 0
19:45365107:G T138P missense_variant 0.71 0
19:45365107:A T138S missense_variant 0.71 0
19:45365107:C T138A missense_variant 0.71 0
19:45354828:T L523I missense_variant 0.71 0
19:45354828:A L523F missense_variant 0.71 0
19:45354828:C L523V missense_variant 0.71 0
19:45364507:T L212H missense_variant 0.71 0
19:45364507:C L212R missense_variant 0.71 0
19:45364507:G L212P missense_variant 0.71 0
19:45353115:C A600G missense_variant 0.71 0
19:45353115:A A600V missense_variant 0.71 0
19:45353115:T A600D missense_variant 0.71 0
19:45353121:A S598L missense_variant 0.71 0
19:45368935:G E81Q missense_variant 0.70 0
19:45368935:T E81K missense_variant 0.70 0
19:45364932:C E167G missense_variant 0.70 0
19:45364932:A E167V missense_variant 0.70 0
19:45364932:G E167A missense_variant 0.70 0
19:45364528:C V205G missense_variant 0.70 0
19:45364528:G V205A missense_variant 0.70 0
19:45364528:T V205E missense_variant 0.70 0
19:45364070:A V289L missense_variant 0.70 0
19:45364064:T G291R missense_variant 0.70 0
19:45364070:T V289M missense_variant 0.70 0
19:45364064:A G291W missense_variant 0.70 0
19:45364070:G V289L missense_variant 0.70 0
19:45364064:G G291R missense_variant 0.70 0
19:45354791:G I535T missense_variant 0.70 0
19:45354791:C I535S missense_variant 0.70 0
19:45354749:T V549E missense_variant 0.70 0
19:45354749:C V549G missense_variant 0.70 0
19:45354749:G V549A missense_variant 0.70 0
19:45354791:T I535N missense_variant 0.70 0
19:45364326:T V242I missense_variant 0.70 0
19:45368679:G F104S missense_variant 0.70 0
19:45368679:C F104C missense_variant 0.70 0
19:45364322:A C243F missense_variant 0.70 0
19:45364322:G C243S missense_variant 0.70 0
19:45364317:A D245Y missense_variant 0.70 0
19:45364322:T C243Y missense_variant 0.70 0
19:45364326:A V242F missense_variant 0.70 0
19:45364326:G V242L missense_variant 0.70 0
19:45368679:T F104Y missense_variant 0.70 0
19:45364317:G D245H missense_variant 0.70 0
19:45364317:T D245N missense_variant 0.70 0
19:45368665:T L109M missense_variant 0.70 0
19:45368665:C L109V missense_variant 0.70 0
19:45365104:T A139T missense_variant 0.70 0
19:45365091:G R143P missense_variant 0.70 0
19:45365091:T R143Q missense_variant 0.70 0
19:45365091:A R143L missense_variant 0.70 0
19:45365104:A A139S missense_variant 0.70 0
19:45365104:G A139P missense_variant 0.70 0
19:45364848:C A195G missense_variant 0.70 0
19:45364848:A A195V missense_variant 0.70 0
19:45364848:T A195D missense_variant 0.70 0
19:45355713:A N499Y missense_variant 0.70 0
19:45355713:G N499H missense_variant 0.70 0
19:45355688:A K507I missense_variant 0.70 0
19:45355682:G E509A missense_variant 0.70 0
19:45355682:C E509G missense_variant 0.70 0
19:45355682:A E509V missense_variant 0.70 0
19:45355688:G K507T missense_variant 0.70 0
19:45355689:C K507E missense_variant 0.70 0
19:45355688:C K507R missense_variant 0.70 0
19:45355713:C N499D missense_variant 0.70 0
19:45355689:G K507Q missense_variant 0.70 0
19:45355695:A S505C missense_variant 0.70 0
19:45355680:G T510P missense_variant 0.70 0
19:45355680:C T510A missense_variant 0.70 0
19:45355695:C S505G missense_variant 0.70 0
19:45355695:G S505R missense_variant 0.70 0
19:45355706:A Q501L missense_variant 0.70 0
19:45355706:C Q501R missense_variant 0.70 0
19:45355680:A T510S missense_variant 0.70 0
19:45355673:G E512A missense_variant 0.70 0
19:45355673:C E512G missense_variant 0.70 0
19:45355673:A E512V missense_variant 0.70 0
19:45355670:G D513A missense_variant 0.70 0
19:45355706:G Q501P missense_variant 0.70 0
19:45355709:A D500V missense_variant 0.70 0
19:45355709:C D500G missense_variant 0.70 0
19:45355670:C D513G missense_variant 0.70 0
19:45355670:A D513V missense_variant 0.70 0
19:45355709:G D500A missense_variant 0.70 0
19:45355712:A N499I missense_variant 0.70 0
19:45355712:C N499S missense_variant 0.70 0
19:45355712:G N499T missense_variant 0.70 0
19:45364292:T R253H missense_variant 0.69 0
19:45364289:A R254L missense_variant 0.69 0
19:45364289:G R254P missense_variant 0.69 0
19:45364289:T R254Q missense_variant 0.69 0
19:45364292:A R253L missense_variant 0.69 0
19:45364292:G R253P missense_variant 0.69 0
19:45368697:A E98V missense_variant 0.69 0
19:45368697:C E98G missense_variant 0.69 0
19:45368697:G E98A missense_variant 0.69 0
19:45361619:A S381F missense_variant 0.69 0
19:45361619:T S381Y missense_variant 0.69 0
19:45361619:C S381C missense_variant 0.69 0
19:45355721:T G496D missense_variant 0.69 0
19:45355721:A G496V missense_variant 0.69 0
19:45355721:G G496A missense_variant 0.69 0
19:45369129:A M42L missense_variant 0.69 0
19:45369111:C K48E missense_variant 0.69 0
19:45369129:G M42L missense_variant 0.69 0
19:45369111:G K48Q missense_variant 0.69 0
19:45369143:A H37L missense_variant 0.69 0
19:45369143:C H37R missense_variant 0.69 0
19:45369143:G H37P missense_variant 0.69 0
19:45368950:G T76P missense_variant 0.68 0
19:45368950:A T76S missense_variant 0.68 0
19:45368950:C T76A missense_variant 0.68 0
19:45352513:A A680V missense_variant 0.68 0
19:45352513:C A680G missense_variant 0.68 0
19:45352513:T A680D missense_variant 0.68 0
19:45364483:G L220P missense_variant 0.67 0
19:45364483:C L220R missense_variant 0.67 0
19:45364483:T L220Q missense_variant 0.67 0
19:45364084:C E284G missense_variant 0.67 0
19:45364084:A E284V missense_variant 0.67 0
19:45364084:G E284A missense_variant 0.67 0
19:45364543:T L200Q missense_variant 0.67 0
19:45364543:C L200R missense_variant 0.67 0
19:45364543:G L200P missense_variant 0.67 0
19:45365097:G Y141S missense_variant 0.67 0
19:45365097:A Y141F missense_variant 0.67 0
19:45365097:C Y141C missense_variant 0.67 0
19:45364287:G T255P missense_variant 0.67 0
19:45364287:C T255A missense_variant 0.67 0
19:45364287:A T255S missense_variant 0.67 0
19:45370161:T R26Q missense_variant 0.66 0
19:45370161:A R26L missense_variant 0.66 0
19:45370161:G R26P missense_variant 0.66 0
19:45364498:A P215L missense_variant 0.66 0
19:45364498:C P215R missense_variant 0.66 0
19:45364498:T P215H missense_variant 0.66 0
19:45352351:T R683Q missense_variant 0.66 0
19:45352351:G R683P missense_variant 0.66 0
19:45352351:A R683L missense_variant 0.66 0
19:45352612:T R647H missense_variant 0.66 0
19:45352612:G R647P missense_variant 0.66 0
19:45352612:A R647L missense_variant 0.66 0
19:45352537:C T672R missense_variant 0.66 0
19:45352610:T E648K missense_variant 0.66 0
19:45352610:G E648Q missense_variant 0.66 0
19:45352645:T R636Q missense_variant 0.66 0
19:45352645:G R636P missense_variant 0.66 0
19:45352645:A R636L missense_variant 0.66 0
19:45352537:A T672M missense_variant 0.66 0
19:45352537:T T672K missense_variant 0.66 0
19:45364424:T D240N missense_variant 0.66 0
19:45364424:G D240H missense_variant 0.66 0
19:45364424:A D240Y missense_variant 0.66 0
19:45368979:G E66A missense_variant 0.66 0
19:45368979:C E66G missense_variant 0.66 0
19:45368979:A E66V missense_variant 0.66 0
19:45357678:T P420H missense_variant 0.66 0
19:45357678:C P420R missense_variant 0.66 0
19:45357678:A P420L missense_variant 0.66 0
19:45361524:G G413R missense_variant 0.66 0
19:45361602:G E387Q missense_variant 0.66 0
19:45351682:C L744V missense_variant 0.66 0
19:45361602:T E387K missense_variant 0.66 0
19:45351682:T L744I missense_variant 0.66 0
19:45361637:T C375Y missense_variant 0.66 0
19:45361637:G C375S missense_variant 0.66 0
19:45361524:T G413S missense_variant 0.66 0
19:45361524:A G413C missense_variant 0.66 0
19:45361637:A C375F missense_variant 0.66 0
19:45361628:A R378L missense_variant 0.66 0
19:45361628:G R378P missense_variant 0.66 0
19:45361628:T R378H missense_variant 0.66 0
19:45361632:G E377Q missense_variant 0.66 0
19:45361632:T E377K missense_variant 0.66 0
19:45361551:A A404S missense_variant 0.66 0
19:45361551:G A404P missense_variant 0.66 0
19:45361542:T V407I missense_variant 0.66 0
19:45361542:G V407L missense_variant 0.66 0
19:45361542:A V407F missense_variant 0.66 0
19:45352529:G G675R missense_variant 0.66 0
19:45352529:A G675C missense_variant 0.66 0
19:45361551:T A404T missense_variant 0.66 0
19:45361538:T S408N missense_variant 0.66 0
19:45361538:G S408T missense_variant 0.66 0
19:45361538:A S408I missense_variant 0.66 0
19:45361584:A D393Y missense_variant 0.66 0
19:45361584:G D393H missense_variant 0.66 0
19:45361584:T D393N missense_variant 0.66 0
19:45361593:A D390Y missense_variant 0.66 0
19:45361593:G D390H missense_variant 0.66 0
19:45361593:T D390N missense_variant 0.66 0
19:45352805:G G615R missense_variant 0.66 0
19:45352805:A G615W missense_variant 0.66 0
19:45352805:T G615R missense_variant 0.66 0
19:45361568:T T398N missense_variant 0.65 0
19:45352337:G D688H missense_variant 0.65 0
19:45361568:A T398I missense_variant 0.65 0
19:45352337:A D688Y missense_variant 0.65 0
19:45352337:T D688N missense_variant 0.65 0
19:45361568:C T398S missense_variant 0.65 0
19:45352619:C Q645E missense_variant 0.65 0
19:45352619:T Q645K missense_variant 0.65 0
19:45365062:A P153S missense_variant 0.65 0
19:45365062:C P153A missense_variant 0.65 0
19:45365062:T P153T missense_variant 0.65 0
19:45352787:C F621V missense_variant 0.65 0
19:45352787:G F621L missense_variant 0.65 0
19:45352787:T F621I missense_variant 0.65 0
19:45352804:A G615V missense_variant 0.65 0
19:45352804:G G615A missense_variant 0.65 0
19:45352804:T G615E missense_variant 0.65 0
19:45364935:G R166P missense_variant 0.64 0
19:45364935:T R166H missense_variant 0.64 0
19:45364487:A D219Y missense_variant 0.64 0
19:45364487:G D219H missense_variant 0.64 0
19:45364487:T D219N missense_variant 0.64 0
19:45364935:A R166L missense_variant 0.64 0
19:45364938:G G165A missense_variant 0.64 0
19:45364938:T G165E missense_variant 0.64 0
19:45364938:A G165V missense_variant 0.64 0
19:45354783:C F538V missense_variant 0.64 0
19:45354783:G F538L missense_variant 0.64 0
19:45354783:T F538I missense_variant 0.64 0
19:45364540:G H201P missense_variant 0.63 0
19:45364540:A H201L missense_variant 0.63 0
19:45364284:C L256V missense_variant 0.63 0
19:45364284:T L256I missense_variant 0.63 0
19:45364284:A L256F missense_variant 0.63 0
19:45364540:C H201R missense_variant 0.63 0
19:45364436:A A236S missense_variant 0.63 0
19:45364436:T A236T missense_variant 0.63 0
19:45364436:G A236P missense_variant 0.63 0
19:45365061:T P153H missense_variant 0.62 0
19:45365061:A P153L missense_variant 0.62 0
19:45364329:A N241Y missense_variant 0.62 0
19:45364329:C N241D missense_variant 0.62 0
19:45364329:G N241H missense_variant 0.62 0
19:45365061:C P153R missense_variant 0.62 0
19:45368955:C S74* stop_gained 0.62 0
19:45368955:T S74* stop_gained 0.62 0
19:45365086:C Q145E missense_variant 0.62 0
19:45365086:T Q145K missense_variant 0.62 0
19:45368662:G S110R missense_variant 0.62 0
19:45368662:C S110G missense_variant 0.62 0
19:45368662:A S110C missense_variant 0.62 0
19:45364538:G A202P missense_variant 0.62 0
19:45364538:T A202T missense_variant 0.62 0
19:45364538:A A202S missense_variant 0.62 0
19:45364311:A M247L missense_variant 0.62 0
19:45364311:G M247L missense_variant 0.62 0
19:45364311:C M247V missense_variant 0.62 0
19:45364310:T M247K missense_variant 0.62 0
19:45364310:G M247T missense_variant 0.62 0
19:45364314:T S246T missense_variant 0.62 0
19:45364310:C M247R missense_variant 0.62 0
19:45364314:C S246A missense_variant 0.62 0
19:45364314:G S246P missense_variant 0.62 0
19:45361623:C R380G missense_variant 0.61 0
19:45361623:A R380W missense_variant 0.61 0
19:45357661:C P426A missense_variant 0.61 0
19:45357663:A T425I missense_variant 0.61 0
19:45357661:T P426T missense_variant 0.61 0
19:45361550:T A404D missense_variant 0.61 0
19:45357632:C F435L missense_variant 0.61 0
19:45357661:A P426S missense_variant 0.61 0
19:45357632:T F435L missense_variant 0.61 0
19:45357663:T T425N missense_variant 0.61 0
19:45357663:C T425S missense_variant 0.61 0
19:45361550:C A404G missense_variant 0.61 0
19:45361550:A A404V missense_variant 0.61 0
19:45363851:C L337R missense_variant 0.61 0
19:45363851:G L337P missense_variant 0.61 0
19:45363851:T L337Q missense_variant 0.61 0
19:45369077:G Y59S missense_variant 0.61 0
19:45369077:C Y59C missense_variant 0.61 0
19:45369077:A Y59F missense_variant 0.61 0
19:45369117:C T46A missense_variant 0.61 0
19:45369108:A T49S missense_variant 0.61 0
19:45369117:A T46S missense_variant 0.61 0
19:45369131:A E41V missense_variant 0.61 0
19:45369117:G T46P missense_variant 0.61 0
19:45369131:G E41A missense_variant 0.61 0
19:45369131:C E41G missense_variant 0.61 0
19:45369108:C T49A missense_variant 0.61 0
19:45369108:G T49P missense_variant 0.61 0
19:45357630:A S436I missense_variant 0.61 0
19:45351721:T E731K missense_variant 0.61 0
19:45351721:G E731Q missense_variant 0.61 0
19:45351718:T D732N missense_variant 0.61 0
19:45351718:G D732H missense_variant 0.61 0
19:45351718:A D732Y missense_variant 0.61 0
19:45351713:G Q733H missense_variant 0.61 0
19:45351713:A Q733H missense_variant 0.61 0
19:45351709:T G735S missense_variant 0.61 0
19:45351709:G G735R missense_variant 0.61 0
19:45351709:A G735C missense_variant 0.61 0
19:45351708:T G735D missense_variant 0.61 0
19:45351708:G G735A missense_variant 0.61 0
19:45351708:A G735V missense_variant 0.61 0
19:45351688:T E742K missense_variant 0.61 0
19:45351688:G E742Q missense_variant 0.61 0
19:45351670:T E748K missense_variant 0.61 0
19:45351670:G E748Q missense_variant 0.61 0
19:45357630:T S436N missense_variant 0.61 0
19:45357630:G S436T missense_variant 0.61 0
19:45364448:T V232I missense_variant 0.60 0
19:45364448:A V232F missense_variant 0.60 0
19:45364448:G V232L missense_variant 0.60 0
19:45364484:C L220V missense_variant 0.60 0
19:45364484:T L220M missense_variant 0.60 0
19:45364442:A D234Y missense_variant 0.60 0
19:45364442:G D234H missense_variant 0.60 0
19:45364442:T D234N missense_variant 0.60 0
19:45364296:A T252S missense_variant 0.60 0
19:45364296:G T252P missense_variant 0.60 0
19:45364296:C T252A missense_variant 0.60 0
19:45351639:A Q758L missense_variant 0.59 0
19:45357699:T G413D missense_variant 0.59 0
19:45357699:G G413A missense_variant 0.59 0
19:45357699:A G413V missense_variant 0.59 0
19:45357673:T D422N missense_variant 0.59 0
19:45357673:G D422H missense_variant 0.59 0
19:45357673:A D422Y missense_variant 0.59 0
19:45351646:G I756L missense_variant 0.59 0
19:45351646:C I756V missense_variant 0.59 0
19:45351646:A I756F missense_variant 0.59 0
19:45351639:G Q758P missense_variant 0.59 0
19:45351639:C Q758R missense_variant 0.59 0
19:45364903:C L177V missense_variant 0.59 0
19:45364903:T L177M missense_variant 0.59 0
19:45364471:G E224A missense_variant 0.59 0
19:45364471:A E224V missense_variant 0.59 0
19:45364471:C E224G missense_variant 0.59 0
19:45364909:G Y175H missense_variant 0.59 0
19:45364909:C Y175D missense_variant 0.59 0
19:45364909:T Y175N missense_variant 0.59 0
19:45364858:G Y192H missense_variant 0.59 0
19:45364858:C Y192D missense_variant 0.59 0
19:45364858:T Y192N missense_variant 0.59 0
19:45364860:T P191Q missense_variant 0.59 0
19:45364860:A P191L missense_variant 0.59 0
19:45364860:C P191R missense_variant 0.59 0
19:45364460:C K228E missense_variant 0.59 0
19:45364460:G K228Q missense_variant 0.59 0
19:45364857:A Y192F missense_variant 0.59 0
19:45364857:C Y192C missense_variant 0.59 0
19:45364857:G Y192S missense_variant 0.59 0
19:45364093:G L281P missense_variant 0.58 0
19:45364093:C L281R missense_variant 0.58 0
19:45364093:T L281Q missense_variant 0.58 0
19:45352252:T V716E missense_variant 0.58 0
19:45352252:C V716G missense_variant 0.58 0
19:45352252:G V716A missense_variant 0.58 0
19:45365088:C A144G missense_variant 0.58 0
19:45365088:T A144E missense_variant 0.58 0
19:45365088:A A144V missense_variant 0.58 0
19:45368655:A R112L missense_variant 0.57 0
19:45368655:G R112P missense_variant 0.57 0
19:45368655:T R112H missense_variant 0.57 0
19:45368674:G G106R missense_variant 0.57 0
19:45368674:T G106R missense_variant 0.57 0
19:45364052:T A295T missense_variant 0.57 0
19:45364055:T E294K missense_variant 0.57 0
19:45364055:G E294Q missense_variant 0.57 0
19:45353094:A G607V missense_variant 0.57 0
19:45353094:T G607E missense_variant 0.57 0
19:45353095:G G607R missense_variant 0.57 0
19:45353095:T G607R missense_variant 0.57 0
19:45364052:A A295S missense_variant 0.57 0
19:45364052:G A295P missense_variant 0.57 0
19:45364951:C F161V missense_variant 0.57 0
19:45364951:T F161I missense_variant 0.57 0
19:45364951:G F161L missense_variant 0.57 0
19:45364428:C N238K missense_variant 0.57 0
19:45364428:T N238K missense_variant 0.57 0
19:45368953:C R75G missense_variant 0.57 0
19:45368951:A R75S missense_variant 0.57 0
19:45368951:G R75S missense_variant 0.57 0
19:45352532:G Y674H missense_variant 0.57 0
19:45352532:C Y674D missense_variant 0.57 0
19:45352532:T Y674N missense_variant 0.57 0
19:45364475:G K223Q missense_variant 0.57 0
19:45364475:C K223E missense_variant 0.57 0
19:45364905:G N176T missense_variant 0.57 0
19:45364905:C N176S missense_variant 0.57 0
19:45364905:A N176I missense_variant 0.57 0
19:45364893:T L180Q missense_variant 0.57 0
19:45364893:G L180P missense_variant 0.57 0
19:45364893:C L180R missense_variant 0.57 0
19:45364842:A Y197F missense_variant 0.57 0
19:45364842:C Y197C missense_variant 0.57 0
19:45364842:G Y197S missense_variant 0.57 0
19:45364511:T Y211N missense_variant 0.56 0
19:45364511:C Y211D missense_variant 0.56 0
19:45364511:G Y211H missense_variant 0.56 0
19:45365128:G D131H missense_variant 0.56 0
19:45365158:T V121M missense_variant 0.56 0
19:45365158:G V121L missense_variant 0.56 0
19:45365158:A V121L missense_variant 0.56 0
19:45365145:T R125H missense_variant 0.56 0
19:45365145:G R125P missense_variant 0.56 0
19:45365145:A R125L missense_variant 0.56 0
19:45365140:T G127R missense_variant 0.56 0
19:45365140:G G127R missense_variant 0.56 0
19:45365140:A G127W missense_variant 0.56 0
19:45365139:T G127E missense_variant 0.56 0
19:45365139:G G127A missense_variant 0.56 0
19:45365139:A G127V missense_variant 0.56 0
19:45365134:T D129N missense_variant 0.56 0
19:45365134:G D129H missense_variant 0.56 0
19:45365134:A D129Y missense_variant 0.56 0
19:45365131:T V130I missense_variant 0.56 0
19:45365131:G V130L missense_variant 0.56 0
19:45365131:A V130F missense_variant 0.56 0
19:45365128:T D131N missense_variant 0.56 0
19:45365128:A D131Y missense_variant 0.56 0
19:45365124:T G132E missense_variant 0.56 0
19:45365124:G G132A missense_variant 0.56 0
19:45365124:A G132V missense_variant 0.56 0
19:45365118:T C134Y missense_variant 0.56 0
19:45365118:G C134S missense_variant 0.56 0
19:45365118:A C134F missense_variant 0.56 0
19:45365042:G E159D missense_variant 0.56 0
19:45365042:A E159D missense_variant 0.56 0
19:45364534:C N203S missense_variant 0.56 0
19:45364534:G N203T missense_variant 0.56 0
19:45364534:A N203I missense_variant 0.56 0
19:45365110:C L137V missense_variant 0.56 0
19:45365110:A L137F missense_variant 0.56 0
19:45365110:T L137I missense_variant 0.56 0
19:45364849:G A195P missense_variant 0.55 0
19:45364849:T A195T missense_variant 0.55 0
19:45364849:A A195S missense_variant 0.55 0
19:45365098:G Y141H missense_variant 0.55 0
19:45365098:T Y141N missense_variant 0.55 0
19:45364505:C L213V missense_variant 0.55 0
19:45364505:T L213M missense_variant 0.55 0
19:45365098:C Y141D missense_variant 0.55 0
19:45353109:G G602A missense_variant 0.54 0
19:45353109:T G602D missense_variant 0.54 0
19:45353109:A G602V missense_variant 0.54 0
19:45364513:G H210P missense_variant 0.54 0
19:45364513:C H210R missense_variant 0.54 0
19:45364513:A H210L missense_variant 0.54 0
19:45365114:T H135Q missense_variant 0.53 0
19:45365114:C H135Q missense_variant 0.53 0
19:45364293:T R253S missense_variant 0.53 0
19:45364293:A R253C missense_variant 0.53 0
19:45364293:C R253G missense_variant 0.53 0
19:45365115:G H135P missense_variant 0.53 0
19:45365115:C H135R missense_variant 0.53 0
19:45365115:A H135L missense_variant 0.53 0
19:45364896:C D179G missense_variant 0.53 0
19:45364896:G D179A missense_variant 0.53 0
19:45364896:A D179V missense_variant 0.53 0
19:45363994:T V314E missense_variant 0.52 0
19:45363994:G V314A missense_variant 0.52 0
19:45363994:C V314G missense_variant 0.52 0
19:45368973:C T68S missense_variant 0.52 0
19:45368973:A T68I missense_variant 0.52 0
19:45368973:T T68N missense_variant 0.52 0
19:45365142:G F126S missense_variant 0.51 0
19:45365142:T F126Y missense_variant 0.51 0
19:45365142:C F126C missense_variant 0.51 0
19:45365043:A E159V missense_variant 0.51 0
19:45365043:C E159G missense_variant 0.51 0
19:45365043:G E159A missense_variant 0.51 0
19:45365044:G E159Q missense_variant 0.51 0
19:45365044:T E159K missense_variant 0.51 0
19:45368957:C C73W missense_variant 0.51 0
19:45364936:T R166S missense_variant 0.50 0
19:45364936:C R166G missense_variant 0.50 0
19:45364936:A R166C missense_variant 0.50 0
19:45368643:G C116S missense_variant 0.50 0
19:45368643:A C116F missense_variant 0.50 0
19:45368643:T C116Y missense_variant 0.50 0
In silico saturation mutagenesis
Alt text Show figure caption
Cancer type Selected cancer type Mutational discovery Index Feature Complexity
(BLCA) Bladder cancer BLCA 0.75 0.17