Top
Note: You're navigating the results of models obtained with IntOGen (2020). A new boostDM version is available here.
FOXA1 PRAD ×
Select a mutation to see further information
Mutation AA change Consequence type BoostDM score IntOGen frequency
14:37592003:C R261G missense_variant 1.00 11
14:37592003:A R261C missense_variant 1.00 4
14:37592026:C M253R missense_variant 1.00 4
14:37591987:C F266C missense_variant 0.97 4
14:37592129:T R219S missense_variant 0.96 4
14:37591986:T F266L missense_variant 0.95 4
14:37592024:C F254V missense_variant 1.00 3
14:37592026:T M253K missense_variant 1.00 3
14:37592008:C Y259C missense_variant 0.98 3
14:37592108:T D226N missense_variant 0.97 3
14:37592026:G M253T missense_variant 1.00 2
14:37592045:T H247N missense_variant 0.98 2
14:37592112:T F224L missense_variant 0.98 2
14:37592129:A R219C missense_variant 0.96 2
14:37591986:C F266L missense_variant 0.95 2
14:37592105:G C227R missense_variant 0.95 2
14:37592107:C D226G missense_variant 0.94 2
14:37591600:C S395C missense_variant 0.94 2
14:37592264:T S174T missense_variant 0.93 2
14:37592586:A M66I missense_variant 0.86 2
14:37592003:T R261S missense_variant 1.00 1
14:37592023:G F254S missense_variant 1.00 1
14:37592021:T E255K missense_variant 0.99 1
14:37592045:A H247Y missense_variant 0.98 1
14:37591987:G F266S missense_variant 0.97 1
14:37592071:A P238L missense_variant 0.94 1
14:37592089:A A232V missense_variant 0.94 1
14:37592041:A P248L missense_variant 0.94 1
14:37592272:T P171Q missense_variant 0.94 1
14:37592035:T S250Y missense_variant 0.94 1
14:37592044:A H247L missense_variant 0.94 1
14:37591576:C N403S missense_variant 0.92 1
14:37592038:A D249V missense_variant 0.86 1
14:37591999:A R262L missense_variant 0.85 1
14:37592278:C A169G missense_variant 0.84 1
14:37591384:T P467H missense_variant 0.83 1
14:37592135:C S217A missense_variant 0.76 1
14:37591981:T C268Y missense_variant 0.59 1
14:37592016:T N256K missense_variant 0.56 1
14:37592124:C H220Q missense_variant 0.55 1
14:37592500:G S95T missense_variant 0.54 1
14:37592023:C F254C missense_variant 1.00 0
14:37592024:T F254I missense_variant 1.00 0
14:37592023:T F254Y missense_variant 1.00 0
14:37592024:G F254L missense_variant 1.00 0
14:37592009:T Y259N missense_variant 1.00 0
14:37592005:C L260W missense_variant 1.00 0
14:37592005:G L260S missense_variant 1.00 0
14:37592009:C Y259D missense_variant 1.00 0
14:37592009:G Y259H missense_variant 1.00 0
14:37592025:A M253I missense_variant 1.00 0
14:37592025:T M253I missense_variant 1.00 0
14:37592025:G M253I missense_variant 1.00 0
14:37592011:G C258S missense_variant 0.99 0
14:37592011:T C258Y missense_variant 0.99 0
14:37592011:A C258F missense_variant 0.99 0
14:37592021:G E255Q missense_variant 0.99 0
14:37592014:A G257V missense_variant 0.99 0
14:37592014:G G257A missense_variant 0.99 0
14:37592014:T G257D missense_variant 0.99 0
14:37592020:C E255G missense_variant 0.99 0
14:37592018:C N256D missense_variant 0.99 0
14:37592020:G E255A missense_variant 0.99 0
14:37592018:A N256Y missense_variant 0.99 0
14:37592017:G N256T missense_variant 0.99 0
14:37592017:A N256I missense_variant 0.99 0
14:37592017:C N256S missense_variant 0.99 0
14:37592020:A E255V missense_variant 0.99 0
14:37592018:G N256H missense_variant 0.99 0
14:37592036:G S250P missense_variant 0.99 0
14:37592036:C S250A missense_variant 0.99 0
14:37592036:T S250T missense_variant 0.99 0
14:37592045:C H247D missense_variant 0.98 0
14:37592159:T Q209K missense_variant 0.98 0
14:37592159:C Q209E missense_variant 0.98 0
14:37592080:T P235Q missense_variant 0.98 0
14:37592080:C P235R missense_variant 0.98 0
14:37592080:A P235L missense_variant 0.98 0
14:37592122:C S221W missense_variant 0.98 0
14:37592122:A S221L missense_variant 0.98 0
14:37592083:C S234C missense_variant 0.98 0
14:37592083:T S234Y missense_variant 0.98 0
14:37592083:A S234F missense_variant 0.98 0
14:37592059:A S242F missense_variant 0.98 0
14:37592153:T Q211K missense_variant 0.98 0
14:37592153:C Q211E missense_variant 0.98 0
14:37592081:T P235T missense_variant 0.98 0
14:37592081:C P235A missense_variant 0.98 0
14:37592081:A P235S missense_variant 0.98 0
14:37592059:T S242Y missense_variant 0.98 0
14:37592059:C S242C missense_variant 0.98 0
14:37592008:A Y259F missense_variant 0.98 0
14:37592008:G Y259S missense_variant 0.98 0
14:37592203:G S194T missense_variant 0.98 0
14:37592213:A L191F missense_variant 0.98 0
14:37592203:T S194N missense_variant 0.98 0
14:37592213:C L191V missense_variant 0.98 0
14:37592213:T L191I missense_variant 0.98 0
14:37592203:A S194I missense_variant 0.98 0
14:37592231:C Q185E missense_variant 0.98 0
14:37592263:A S174L missense_variant 0.98 0
14:37592263:C S174W missense_variant 0.98 0
14:37592231:T Q185K missense_variant 0.98 0
14:37592196:C I196M missense_variant 0.98 0
14:37592112:C F224L missense_variant 0.98 0
14:37592069:A G239C missense_variant 0.97 0
14:37592069:G G239R missense_variant 0.97 0
14:37592069:T G239S missense_variant 0.97 0
14:37592062:A G241V missense_variant 0.97 0
14:37592063:G G241R missense_variant 0.97 0
14:37592063:T G241S missense_variant 0.97 0
14:37592108:G D226H missense_variant 0.97 0
14:37592108:A D226Y missense_variant 0.97 0
14:37592068:A G239V missense_variant 0.97 0
14:37592068:G G239A missense_variant 0.97 0
14:37592104:T C227Y missense_variant 0.97 0
14:37592104:G C227S missense_variant 0.97 0
14:37592104:A C227F missense_variant 0.97 0
14:37592128:A R219L missense_variant 0.97 0
14:37592128:G R219P missense_variant 0.97 0
14:37592128:T R219H missense_variant 0.97 0
14:37592068:T G239D missense_variant 0.97 0
14:37592093:T V231M missense_variant 0.97 0
14:37592093:G V231L missense_variant 0.97 0
14:37592093:A V231L missense_variant 0.97 0
14:37592063:A G241C missense_variant 0.97 0
14:37592086:T R233H missense_variant 0.97 0
14:37592086:G R233P missense_variant 0.97 0
14:37592086:A R233L missense_variant 0.97 0
14:37592062:T G241D missense_variant 0.97 0
14:37592062:G G241A missense_variant 0.97 0
14:37592015:G G257R missense_variant 0.97 0
14:37592015:A G257C missense_variant 0.97 0
14:37592015:T G257S missense_variant 0.97 0
14:37592012:C C258G missense_variant 0.97 0
14:37592012:T C258S missense_variant 0.97 0
14:37592012:G C258R missense_variant 0.97 0
14:37592053:G W244S missense_variant 0.97 0
14:37592052:A W244C missense_variant 0.97 0
14:37592052:G W244C missense_variant 0.97 0
14:37592053:A W244L missense_variant 0.97 0
14:37592146:G R213P missense_variant 0.97 0
14:37592161:T R208Q missense_variant 0.97 0
14:37592142:A W214C missense_variant 0.97 0
14:37592142:G W214C missense_variant 0.97 0
14:37592143:A W214L missense_variant 0.97 0
14:37592161:A R208L missense_variant 0.97 0
14:37592146:A R213L missense_variant 0.97 0
14:37592146:T R213H missense_variant 0.97 0
14:37592161:G R208P missense_variant 0.97 0
14:37592143:G W214S missense_variant 0.97 0
14:37591988:G F266L missense_variant 0.97 0
14:37591988:C F266V missense_variant 0.97 0
14:37591987:T F266Y missense_variant 0.97 0
14:37591988:T F266I missense_variant 0.97 0
14:37591435:T I450N missense_variant 0.97 0
14:37591435:G I450T missense_variant 0.97 0
14:37591435:C I450S missense_variant 0.97 0
14:37591621:C L388R missense_variant 0.97 0
14:37591621:T L388Q missense_variant 0.97 0
14:37591621:G L388P missense_variant 0.97 0
14:37591370:T S472T missense_variant 0.97 0
14:37591370:C S472A missense_variant 0.97 0
14:37591370:G S472P missense_variant 0.97 0
14:37592181:G M201I missense_variant 0.97 0
14:37592181:A M201I missense_variant 0.97 0
14:37592201:T E195K missense_variant 0.97 0
14:37592180:T D202N missense_variant 0.97 0
14:37592181:T M201I missense_variant 0.97 0
14:37592180:G D202H missense_variant 0.97 0
14:37592180:A D202Y missense_variant 0.97 0
14:37592201:G E195Q missense_variant 0.97 0
14:37592240:A A182S missense_variant 0.97 0
14:37592241:T M181I missense_variant 0.97 0
14:37592241:G M181I missense_variant 0.97 0
14:37592241:A M181I missense_variant 0.97 0
14:37592240:T A182T missense_variant 0.97 0
14:37592240:G A182P missense_variant 0.97 0
14:37592106:C D226E missense_variant 0.96 0
14:37592106:T D226E missense_variant 0.96 0
14:37592139:G Q215H missense_variant 0.96 0
14:37592139:A Q215H missense_variant 0.96 0
14:37592129:C R219G missense_variant 0.96 0
14:37592473:G M104T missense_variant 0.96 0
14:37592473:T M104K missense_variant 0.96 0
14:37592473:C M104R missense_variant 0.96 0
14:37592178:C D202E missense_variant 0.96 0
14:37592178:T D202E missense_variant 0.96 0
14:37591816:A A323V missense_variant 0.95 0
14:37591816:C A323G missense_variant 0.95 0
14:37591816:T A323E missense_variant 0.95 0
14:37592092:G V231A missense_variant 0.95 0
14:37592119:T L222Q missense_variant 0.95 0
14:37592119:G L222P missense_variant 0.95 0
14:37592119:C L222R missense_variant 0.95 0
14:37592113:T F224Y missense_variant 0.95 0
14:37592113:G F224S missense_variant 0.95 0
14:37592113:C F224C missense_variant 0.95 0
14:37592105:T C227S missense_variant 0.95 0
14:37592105:C C227G missense_variant 0.95 0
14:37592102:T F228I missense_variant 0.95 0
14:37592102:G F228L missense_variant 0.95 0
14:37592102:C F228V missense_variant 0.95 0
14:37592101:T F228Y missense_variant 0.95 0
14:37592101:G F228S missense_variant 0.95 0
14:37592101:C F228C missense_variant 0.95 0
14:37592098:T V229D missense_variant 0.95 0
14:37592098:G V229A missense_variant 0.95 0
14:37592098:C V229G missense_variant 0.95 0
14:37592092:T V231E missense_variant 0.95 0
14:37592092:C V231G missense_variant 0.95 0
14:37592047:T L246Q missense_variant 0.95 0
14:37592047:G L246P missense_variant 0.95 0
14:37592047:C L246R missense_variant 0.95 0
14:37592117:G S223P missense_variant 0.95 0
14:37592117:C S223A missense_variant 0.95 0
14:37592117:T S223T missense_variant 0.95 0
14:37592192:T Q198K missense_variant 0.95 0
14:37592192:C Q198E missense_variant 0.95 0
14:37592184:C I200M missense_variant 0.95 0
14:37592171:T P205T missense_variant 0.95 0
14:37592171:C P205A missense_variant 0.95 0
14:37592171:A P205S missense_variant 0.95 0
14:37592030:A N252Y missense_variant 0.94 0
14:37592027:C M253V missense_variant 0.94 0
14:37592027:G M253L missense_variant 0.94 0
14:37592029:A N252I missense_variant 0.94 0
14:37592030:G N252H missense_variant 0.94 0
14:37592029:C N252S missense_variant 0.94 0
14:37592030:C N252D missense_variant 0.94 0
14:37592029:G N252T missense_variant 0.94 0
14:37592027:A M253L missense_variant 0.94 0
14:37592144:G W214R missense_variant 0.94 0
14:37592144:C W214G missense_variant 0.94 0
14:37592173:T F204Y missense_variant 0.94 0
14:37592174:T F204I missense_variant 0.94 0
14:37592174:C F204V missense_variant 0.94 0
14:37592174:G F204L missense_variant 0.94 0
14:37592054:C W244G missense_variant 0.94 0
14:37592054:G W244R missense_variant 0.94 0
14:37592054:T W244R missense_variant 0.94 0
14:37592057:C Y243D missense_variant 0.94 0
14:37592057:G Y243H missense_variant 0.94 0
14:37592057:T Y243N missense_variant 0.94 0
14:37592173:G F204S missense_variant 0.94 0
14:37592168:T Y206N missense_variant 0.94 0
14:37592168:G Y206H missense_variant 0.94 0
14:37592168:C Y206D missense_variant 0.94 0
14:37592165:T Y207N missense_variant 0.94 0
14:37592173:C F204C missense_variant 0.94 0
14:37592165:G Y207H missense_variant 0.94 0
14:37592165:C Y207D missense_variant 0.94 0
14:37592144:T W214R missense_variant 0.94 0
14:37591517:T A423T missense_variant 0.94 0
14:37591517:G A423P missense_variant 0.94 0
14:37591517:A A423S missense_variant 0.94 0
14:37592107:A D226V missense_variant 0.94 0
14:37592065:A K240M missense_variant 0.94 0
14:37592065:C K240R missense_variant 0.94 0
14:37592065:G K240T missense_variant 0.94 0
14:37592066:C K240E missense_variant 0.94 0
14:37592066:G K240Q missense_variant 0.94 0
14:37592074:A K237M missense_variant 0.94 0
14:37592074:C K237R missense_variant 0.94 0
14:37592074:G K237T missense_variant 0.94 0
14:37592075:C K237E missense_variant 0.94 0
14:37592075:G K237Q missense_variant 0.94 0
14:37592077:A D236V missense_variant 0.94 0
14:37592077:C D236G missense_variant 0.94 0
14:37592077:G D236A missense_variant 0.94 0
14:37592095:A K230M missense_variant 0.94 0
14:37592095:C K230R missense_variant 0.94 0
14:37592095:G K230T missense_variant 0.94 0
14:37592096:C K230E missense_variant 0.94 0
14:37592096:G K230Q missense_variant 0.94 0
14:37592107:G D226A missense_variant 0.94 0
14:37592110:A N225I missense_variant 0.94 0
14:37592110:C N225S missense_variant 0.94 0
14:37592110:G N225T missense_variant 0.94 0
14:37592111:A N225Y missense_variant 0.94 0
14:37592111:C N225D missense_variant 0.94 0
14:37592111:G N225H missense_variant 0.94 0
14:37592125:A H220L missense_variant 0.94 0
14:37592125:C H220R missense_variant 0.94 0
14:37592125:G H220P missense_variant 0.94 0
14:37591600:A S395F missense_variant 0.94 0
14:37591600:T S395Y missense_variant 0.94 0
14:37591429:A P452L missense_variant 0.94 0
14:37591429:T P452H missense_variant 0.94 0
14:37591429:C P452R missense_variant 0.94 0
14:37592089:T A232E missense_variant 0.94 0
14:37592071:C P238R missense_variant 0.94 0
14:37592126:A H220Y missense_variant 0.94 0
14:37592072:T P238T missense_variant 0.94 0
14:37592126:C H220D missense_variant 0.94 0
14:37592072:C P238A missense_variant 0.94 0
14:37592126:T H220N missense_variant 0.94 0
14:37592072:A P238S missense_variant 0.94 0
14:37592071:T P238Q missense_variant 0.94 0
14:37592089:C A232G missense_variant 0.94 0
14:37592116:T S223Y missense_variant 0.94 0
14:37592116:A S223F missense_variant 0.94 0
14:37592116:C S223C missense_variant 0.94 0
14:37592170:A P205L missense_variant 0.94 0
14:37592050:C T245R missense_variant 0.94 0
14:37592170:C P205R missense_variant 0.94 0
14:37592170:T P205H missense_variant 0.94 0
14:37592050:T T245K missense_variant 0.94 0
14:37592041:C P248R missense_variant 0.94 0
14:37592041:T P248Q missense_variant 0.94 0
14:37592042:A P248S missense_variant 0.94 0
14:37592050:A T245M missense_variant 0.94 0
14:37592042:T P248T missense_variant 0.94 0
14:37592141:C Q215E missense_variant 0.94 0
14:37592141:T Q215K missense_variant 0.94 0
14:37592042:C P248A missense_variant 0.94 0
14:37592150:C Q212E missense_variant 0.94 0
14:37592150:T Q212K missense_variant 0.94 0
14:37592252:A L178F missense_variant 0.94 0
14:37592252:C L178V missense_variant 0.94 0
14:37592252:T L178I missense_variant 0.94 0
14:37592273:C P171A missense_variant 0.94 0
14:37592234:T Q184K missense_variant 0.94 0
14:37592239:T A182D missense_variant 0.94 0
14:37592239:C A182G missense_variant 0.94 0
14:37592239:A A182V missense_variant 0.94 0
14:37592269:A P172L missense_variant 0.94 0
14:37592254:C S177W missense_variant 0.94 0
14:37592254:A S177L missense_variant 0.94 0
14:37592269:C P172R missense_variant 0.94 0
14:37592269:T P172H missense_variant 0.94 0
14:37592270:A P172S missense_variant 0.94 0
14:37592270:C P172A missense_variant 0.94 0
14:37592270:T P172T missense_variant 0.94 0
14:37592272:A P171L missense_variant 0.94 0
14:37592272:C P171R missense_variant 0.94 0
14:37592273:A P171S missense_variant 0.94 0
14:37592234:C Q184E missense_variant 0.94 0
14:37592273:T P171T missense_variant 0.94 0
14:37592209:C T192R missense_variant 0.94 0
14:37592245:T T180N missense_variant 0.94 0
14:37592245:C T180S missense_variant 0.94 0
14:37592245:A T180I missense_variant 0.94 0
14:37592209:A T192M missense_variant 0.94 0
14:37592225:T P187T missense_variant 0.94 0
14:37592225:C P187A missense_variant 0.94 0
14:37592225:A P187S missense_variant 0.94 0
14:37592209:T T192K missense_variant 0.94 0
14:37592197:G I196T missense_variant 0.94 0
14:37592267:T Y173N missense_variant 0.94 0
14:37592267:G Y173H missense_variant 0.94 0
14:37592267:C Y173D missense_variant 0.94 0
14:37592261:T Y175N missense_variant 0.94 0
14:37592261:G Y175H missense_variant 0.94 0
14:37592261:C Y175D missense_variant 0.94 0
14:37592257:T I176N missense_variant 0.94 0
14:37592257:G I176T missense_variant 0.94 0
14:37592257:C I176S missense_variant 0.94 0
14:37592251:T L178H missense_variant 0.94 0
14:37592251:G L178P missense_variant 0.94 0
14:37592251:C L178R missense_variant 0.94 0
14:37592242:T M181K missense_variant 0.94 0
14:37592242:G M181T missense_variant 0.94 0
14:37592242:C M181R missense_variant 0.94 0
14:37592236:T I183N missense_variant 0.94 0
14:37592236:G I183T missense_variant 0.94 0
14:37592236:C I183S missense_variant 0.94 0
14:37592212:T L191H missense_variant 0.94 0
14:37592212:G L191P missense_variant 0.94 0
14:37592212:C L191R missense_variant 0.94 0
14:37592206:T L193Q missense_variant 0.94 0
14:37592206:G L193P missense_variant 0.94 0
14:37592206:C L193R missense_variant 0.94 0
14:37592197:T I196N missense_variant 0.94 0
14:37592197:C I196S missense_variant 0.94 0
14:37592195:T Y197N missense_variant 0.94 0
14:37592195:G Y197H missense_variant 0.94 0
14:37592195:C Y197D missense_variant 0.94 0
14:37592189:T W199R missense_variant 0.94 0
14:37592189:G W199R missense_variant 0.94 0
14:37592189:C W199G missense_variant 0.94 0
14:37592185:T I200N missense_variant 0.94 0
14:37592185:G I200T missense_variant 0.94 0
14:37592185:C I200S missense_variant 0.94 0
14:37592182:C M201R missense_variant 0.94 0
14:37592182:G M201T missense_variant 0.94 0
14:37592182:T M201K missense_variant 0.94 0
14:37592035:C S250C missense_variant 0.94 0
14:37592227:A A186V missense_variant 0.94 0
14:37592227:C A186G missense_variant 0.94 0
14:37592227:T A186E missense_variant 0.94 0
14:37592035:A S250F missense_variant 0.94 0
14:37592048:C L246V missense_variant 0.94 0
14:37592048:T L246M missense_variant 0.94 0
14:37592224:T P187H missense_variant 0.94 0
14:37592224:A P187L missense_variant 0.94 0
14:37592224:C P187R missense_variant 0.94 0
14:37592044:C H247R missense_variant 0.94 0
14:37592044:G H247P missense_variant 0.94 0
14:37592215:C M190R missense_variant 0.93 0
14:37592255:C S177A missense_variant 0.93 0
14:37592215:T M190K missense_variant 0.93 0
14:37592215:G M190T missense_variant 0.93 0
14:37592255:G S177P missense_variant 0.93 0
14:37592264:G S174P missense_variant 0.93 0
14:37592264:C S174A missense_variant 0.93 0
14:37592255:T S177T missense_variant 0.93 0
14:37592413:G M124T missense_variant 0.93 0
14:37592413:C M124R missense_variant 0.93 0
14:37592413:T M124K missense_variant 0.93 0
14:37592457:T S109R missense_variant 0.93 0
14:37592457:C S109R missense_variant 0.93 0
14:37594918:G Y19H missense_variant 0.93 0
14:37594968:G L2S missense_variant 0.93 0
14:37594921:C Y18D missense_variant 0.93 0
14:37594918:T Y19N missense_variant 0.93 0
14:37594918:C Y19D missense_variant 0.93 0
14:37594921:G Y18H missense_variant 0.93 0
14:37594921:T Y18N missense_variant 0.93 0
14:37594930:C W15G missense_variant 0.93 0
14:37594930:G W15R missense_variant 0.93 0
14:37594930:T W15R missense_variant 0.93 0
14:37594953:C M7R missense_variant 0.93 0
14:37594953:T M7K missense_variant 0.93 0
14:37594953:G M7T missense_variant 0.93 0
14:37592371:T M138K missense_variant 0.93 0
14:37592371:G M138T missense_variant 0.93 0
14:37592371:C M138R missense_variant 0.93 0
14:37592216:C M190V missense_variant 0.93 0
14:37592216:A M190L missense_variant 0.93 0
14:37592204:G S194R missense_variant 0.93 0
14:37592204:C S194G missense_variant 0.93 0
14:37592204:A S194C missense_variant 0.93 0
14:37592216:G M190L missense_variant 0.93 0
14:37592230:G Q185P missense_variant 0.92 0
14:37592230:A Q185L missense_variant 0.92 0
14:37592230:C Q185R missense_variant 0.92 0
14:37591625:A H387Y missense_variant 0.92 0
14:37591456:C S443W missense_variant 0.92 0
14:37591456:A S443L missense_variant 0.92 0
14:37591625:T H387N missense_variant 0.92 0
14:37591625:C H387D missense_variant 0.92 0
14:37591498:C Y429C missense_variant 0.92 0
14:37591498:G Y429S missense_variant 0.92 0
14:37591498:A Y429F missense_variant 0.92 0
14:37594922:C S17R missense_variant 0.92 0
14:37592681:A N35Y missense_variant 0.92 0
14:37592681:C N35D missense_variant 0.92 0
14:37594922:T S17R missense_variant 0.92 0
14:37594969:C L2V missense_variant 0.92 0
14:37594969:T L2I missense_variant 0.92 0
14:37592681:G N35H missense_variant 0.92 0
14:37592114:G F224L missense_variant 0.92 0
14:37592114:C F224V missense_variant 0.92 0
14:37592114:T F224I missense_variant 0.92 0
14:37592674:G G37A missense_variant 0.92 0
14:37592674:T G37D missense_variant 0.92 0
14:37592674:A G37V missense_variant 0.92 0
14:37592549:T P79T missense_variant 0.92 0
14:37592549:C P79A missense_variant 0.92 0
14:37592549:A P79S missense_variant 0.92 0
14:37591576:A N403I missense_variant 0.92 0
14:37591576:G N403T missense_variant 0.92 0
14:37592560:C A75G missense_variant 0.91 0
14:37594906:C Q23E missense_variant 0.91 0
14:37592560:T A75D missense_variant 0.91 0
14:37594906:T Q23K missense_variant 0.91 0
14:37592560:A A75V missense_variant 0.91 0
14:37592179:A D202V missense_variant 0.91 0
14:37592179:G D202A missense_variant 0.91 0
14:37592179:C D202G missense_variant 0.91 0
14:37592132:G I218L missense_variant 0.91 0
14:37592140:G Q215P missense_variant 0.91 0
14:37592140:C Q215R missense_variant 0.91 0
14:37592140:A Q215L missense_variant 0.91 0
14:37592138:G N216H missense_variant 0.91 0
14:37592138:C N216D missense_variant 0.91 0
14:37592138:A N216Y missense_variant 0.91 0
14:37592137:G N216T missense_variant 0.91 0
14:37592137:A N216I missense_variant 0.91 0
14:37592137:C N216S missense_variant 0.91 0
14:37592164:G Y207S missense_variant 0.91 0
14:37592164:C Y207C missense_variant 0.91 0
14:37592164:A Y207F missense_variant 0.91 0
14:37592158:G Q209P missense_variant 0.91 0
14:37592158:C Q209R missense_variant 0.91 0
14:37592158:A Q209L missense_variant 0.91 0
14:37592156:G N210H missense_variant 0.91 0
14:37592156:C N210D missense_variant 0.91 0
14:37592132:A I218F missense_variant 0.91 0
14:37592156:A N210Y missense_variant 0.91 0
14:37592155:G N210T missense_variant 0.91 0
14:37592155:C N210S missense_variant 0.91 0
14:37592155:A N210I missense_variant 0.91 0
14:37592152:G Q211P missense_variant 0.91 0
14:37592152:C Q211R missense_variant 0.91 0
14:37592152:A Q211L missense_variant 0.91 0
14:37592132:C I218V missense_variant 0.91 0
14:37592149:G Q212P missense_variant 0.91 0
14:37592149:C Q212R missense_variant 0.91 0
14:37592149:A Q212L missense_variant 0.91 0
14:37591411:T A458E missense_variant 0.90 0
14:37591411:C A458G missense_variant 0.90 0
14:37591411:A A458V missense_variant 0.90 0
14:37592258:C I176V missense_variant 0.90 0
14:37592237:G I183L missense_variant 0.90 0
14:37592233:A Q184L missense_variant 0.90 0
14:37592237:A I183F missense_variant 0.90 0
14:37592260:G Y175S missense_variant 0.90 0
14:37592249:A I179F missense_variant 0.90 0
14:37592233:G Q184P missense_variant 0.90 0
14:37592258:G I176L missense_variant 0.90 0
14:37592243:C M181V missense_variant 0.90 0
14:37592243:A M181L missense_variant 0.90 0
14:37592237:C I183V missense_variant 0.90 0
14:37592249:C I179V missense_variant 0.90 0
14:37592233:C Q184R missense_variant 0.90 0
14:37592260:C Y175C missense_variant 0.90 0
14:37592260:A Y175F missense_variant 0.90 0
14:37592249:G I179L missense_variant 0.90 0
14:37592258:A I176F missense_variant 0.90 0
14:37592243:G M181L missense_variant 0.90 0
14:37592186:C I200V missense_variant 0.90 0
14:37592266:A Y173F missense_variant 0.90 0
14:37592266:C Y173C missense_variant 0.90 0
14:37592266:G Y173S missense_variant 0.90 0
14:37592275:A K170M missense_variant 0.90 0
14:37592275:C K170R missense_variant 0.90 0
14:37592275:G K170T missense_variant 0.90 0
14:37592183:A M201L missense_variant 0.90 0
14:37592218:A K189M missense_variant 0.90 0
14:37592210:G T192P missense_variant 0.90 0
14:37592186:A I200F missense_variant 0.90 0
14:37592186:G I200L missense_variant 0.90 0
14:37592183:C M201V missense_variant 0.90 0
14:37592210:A T192S missense_variant 0.90 0
14:37592219:G K189Q missense_variant 0.90 0
14:37592194:A Y197F missense_variant 0.90 0
14:37592194:C Y197C missense_variant 0.90 0
14:37592194:G Y197S missense_variant 0.90 0
14:37592219:C K189E missense_variant 0.90 0
14:37592218:G K189T missense_variant 0.90 0
14:37592210:C T192A missense_variant 0.90 0
14:37592218:C K189R missense_variant 0.90 0
14:37592198:G I196L missense_variant 0.90 0
14:37592183:G M201L missense_variant 0.90 0
14:37592198:C I196V missense_variant 0.90 0
14:37592198:A I196F missense_variant 0.90 0
14:37592151:A Q211H missense_variant 0.89 0
14:37592151:G Q211H missense_variant 0.89 0
14:37592702:G S28P missense_variant 0.88 0
14:37592702:C S28A missense_variant 0.88 0
14:37592702:T S28T missense_variant 0.88 0
14:37591687:C A366G missense_variant 0.88 0
14:37591687:A A366V missense_variant 0.88 0
14:37591687:T A366E missense_variant 0.88 0
14:37592284:T P167Q missense_variant 0.88 0
14:37592284:C P167R missense_variant 0.88 0
14:37592284:A P167L missense_variant 0.88 0
14:37591520:T Q422K missense_variant 0.88 0
14:37591520:C Q422E missense_variant 0.88 0
14:37592596:C S63C missense_variant 0.88 0
14:37592596:T S63Y missense_variant 0.88 0
14:37592596:A S63F missense_variant 0.88 0
14:37591387:A R466I missense_variant 0.88 0
14:37591418:T E456K missense_variant 0.88 0
14:37591418:G E456Q missense_variant 0.88 0
14:37591387:T R466K missense_variant 0.88 0
14:37591387:G R466T missense_variant 0.88 0
14:37592123:G S221P missense_variant 0.88 0
14:37592060:G S242P missense_variant 0.88 0
14:37592123:T S221T missense_variant 0.88 0
14:37592060:T S242T missense_variant 0.88 0
14:37592176:C L203R missense_variant 0.88 0
14:37592176:G L203P missense_variant 0.88 0
14:37592060:C S242A missense_variant 0.88 0
14:37592176:T L203H missense_variant 0.88 0
14:37592123:C S221A missense_variant 0.88 0
14:37591588:A P399L missense_variant 0.88 0
14:37591588:T P399Q missense_variant 0.88 0
14:37591588:C P399R missense_variant 0.88 0
14:37591582:T S401Y missense_variant 0.88 0
14:37591582:C S401C missense_variant 0.88 0
14:37591582:A S401F missense_variant 0.88 0
14:37592704:A S27F missense_variant 0.88 0
14:37592704:C S27C missense_variant 0.88 0
14:37592704:T S27Y missense_variant 0.88 0
14:37592290:T S165N missense_variant 0.88 0
14:37592290:A S165I missense_variant 0.88 0
14:37592290:G S165T missense_variant 0.88 0
14:37592311:C D158G missense_variant 0.88 0
14:37592311:G D158A missense_variant 0.88 0
14:37592311:A D158V missense_variant 0.88 0
14:37594959:T V5E missense_variant 0.88 0
14:37594959:C V5G missense_variant 0.88 0
14:37592672:T L38M missense_variant 0.88 0
14:37592672:C L38V missense_variant 0.88 0
14:37594959:G V5A missense_variant 0.88 0
14:37592084:C S234A missense_variant 0.88 0
14:37592084:T S234T missense_variant 0.88 0
14:37592084:G S234P missense_variant 0.88 0
14:37592464:C A107G missense_variant 0.87 0
14:37592464:T A107E missense_variant 0.87 0
14:37592464:A A107V missense_variant 0.87 0
14:37591424:A A454S missense_variant 0.87 0
14:37591424:G A454P missense_variant 0.87 0
14:37591424:T A454T missense_variant 0.87 0
14:37592635:G M50T missense_variant 0.87 0
14:37592635:T M50K missense_variant 0.87 0
14:37592635:C M50R missense_variant 0.87 0
14:37591423:T A454D missense_variant 0.87 0
14:37591423:A A454V missense_variant 0.87 0
14:37591423:C A454G missense_variant 0.87 0
14:37592131:T I218N missense_variant 0.87 0
14:37592131:C I218S missense_variant 0.87 0
14:37592131:G I218T missense_variant 0.87 0
14:37592248:C I179S missense_variant 0.87 0
14:37592248:G I179T missense_variant 0.87 0
14:37592248:T I179N missense_variant 0.87 0
14:37591729:A P352L missense_variant 0.87 0
14:37591729:C P352R missense_variant 0.87 0
14:37591729:T P352Q missense_variant 0.87 0
14:37592392:A A131V missense_variant 0.87 0
14:37592392:T A131E missense_variant 0.87 0
14:37592392:C A131G missense_variant 0.87 0
14:37592038:C D249G missense_variant 0.86 0
14:37592038:G D249A missense_variant 0.86 0
14:37592652:T M44I missense_variant 0.86 0
14:37592652:A M44I missense_variant 0.86 0
14:37592652:G M44I missense_variant 0.86 0
14:37591645:T A380E missense_variant 0.86 0
14:37591645:C A380G missense_variant 0.86 0
14:37591645:A A380V missense_variant 0.86 0
14:37592586:T M66I missense_variant 0.86 0
14:37592586:G M66I missense_variant 0.86 0
14:37591396:T V463E missense_variant 0.86 0
14:37592341:T L148Q missense_variant 0.86 0
14:37591396:C V463G missense_variant 0.86 0
14:37591396:G V463A missense_variant 0.86 0
14:37592341:C L148R missense_variant 0.86 0
14:37592341:G L148P missense_variant 0.86 0
14:37591400:A G462C missense_variant 0.86 0
14:37591400:G G462R missense_variant 0.86 0
14:37591400:T G462S missense_variant 0.86 0
14:37592629:C T52S missense_variant 0.85 0
14:37592629:A T52I missense_variant 0.85 0
14:37592381:C N135D missense_variant 0.85 0
14:37592381:G N135H missense_variant 0.85 0
14:37591501:T P428H missense_variant 0.85 0
14:37591501:C P428R missense_variant 0.85 0
14:37591501:A P428L missense_variant 0.85 0
14:37592629:T T52N missense_variant 0.85 0
14:37592381:A N135Y missense_variant 0.85 0
14:37591417:C E456G missense_variant 0.85 0
14:37591417:A E456V missense_variant 0.85 0
14:37591417:G E456A missense_variant 0.85 0
14:37591732:C T351S missense_variant 0.85 0
14:37591732:A T351I missense_variant 0.85 0
14:37591732:T T351N missense_variant 0.85 0
14:37591622:C L388V missense_variant 0.85 0
14:37591622:T L388M missense_variant 0.85 0
14:37592552:A S78C missense_variant 0.85 0
14:37591903:G R294P missense_variant 0.85 0
14:37591903:T R294H missense_variant 0.85 0
14:37591903:A R294L missense_variant 0.85 0
14:37592552:G S78R missense_variant 0.85 0
14:37592552:C S78G missense_variant 0.85 0
14:37592220:C S188R missense_variant 0.85 0
14:37592220:T S188R missense_variant 0.85 0
14:37591999:G R262P missense_variant 0.85 0
14:37592365:C P140R missense_variant 0.85 0
14:37592365:T P140H missense_variant 0.85 0
14:37591660:A P375L missense_variant 0.85 0
14:37591660:T P375Q missense_variant 0.85 0
14:37592002:A R261L missense_variant 0.85 0
14:37592365:A P140L missense_variant 0.85 0
14:37592002:T R261H missense_variant 0.85 0
14:37591999:T R262H missense_variant 0.85 0
14:37592002:G R261P missense_variant 0.85 0
14:37591660:C P375R missense_variant 0.85 0
14:37591984:G K267T missense_variant 0.85 0
14:37591984:C K267R missense_variant 0.85 0
14:37591984:A K267M missense_variant 0.85 0
14:37591708:C P359R missense_variant 0.85 0
14:37591708:T P359H missense_variant 0.85 0
14:37591708:A P359L missense_variant 0.85 0
14:37591640:C H382D missense_variant 0.85 0
14:37591640:A H382Y missense_variant 0.85 0
14:37591640:T H382N missense_variant 0.85 0
14:37592653:G M44T missense_variant 0.84 0
14:37592653:T M44K missense_variant 0.84 0
14:37592645:G Y47H missense_variant 0.84 0
14:37592645:C Y47D missense_variant 0.84 0
14:37592645:T Y47N missense_variant 0.84 0
14:37592653:C M44R missense_variant 0.84 0
14:37591775:C H337D missense_variant 0.84 0
14:37591775:T H337N missense_variant 0.84 0
14:37591775:A H337Y missense_variant 0.84 0
14:37592626:G M53T missense_variant 0.84 0
14:37592626:C M53R missense_variant 0.84 0
14:37592626:T M53K missense_variant 0.84 0
14:37591577:C N403D missense_variant 0.84 0
14:37591577:G N403H missense_variant 0.84 0
14:37591577:A N403Y missense_variant 0.84 0
14:37592308:T A159D missense_variant 0.84 0
14:37592308:A A159V missense_variant 0.84 0
14:37592308:C A159G missense_variant 0.84 0
14:37592570:A G72C missense_variant 0.84 0
14:37592569:G G72A missense_variant 0.84 0
14:37592569:T G72D missense_variant 0.84 0
14:37592569:A G72V missense_variant 0.84 0
14:37592570:G G72R missense_variant 0.84 0
14:37592570:T G72S missense_variant 0.84 0
14:37592405:C L127V missense_variant 0.84 0
14:37592405:T L127M missense_variant 0.84 0
14:37591573:G N404T missense_variant 0.84 0
14:37591573:A N404I missense_variant 0.84 0
14:37591573:C N404S missense_variant 0.84 0
14:37592282:A H168Y missense_variant 0.84 0
14:37592584:A S67F missense_variant 0.84 0
14:37592584:C S67C missense_variant 0.84 0
14:37592584:T S67Y missense_variant 0.84 0
14:37592282:T H168N missense_variant 0.84 0
14:37592282:C H168D missense_variant 0.84 0
14:37592278:T A169D missense_variant 0.84 0
14:37592278:A A169V missense_variant 0.84 0
14:37591385:A P467S missense_variant 0.83 0
14:37591384:C P467R missense_variant 0.83 0
14:37591384:A P467L missense_variant 0.83 0
14:37591385:T P467T missense_variant 0.83 0
14:37591385:C P467A missense_variant 0.83 0
14:37591471:T P438H missense_variant 0.83 0
14:37591471:A P438L missense_variant 0.83 0
14:37591471:C P438R missense_variant 0.83 0
14:37591564:T S407Y missense_variant 0.83 0
14:37591550:C Q412E missense_variant 0.83 0
14:37591564:C S407C missense_variant 0.83 0
14:37591511:C Q425E missense_variant 0.83 0
14:37591564:A S407F missense_variant 0.83 0
14:37591511:T Q425K missense_variant 0.83 0
14:37591550:T Q412K missense_variant 0.83 0
14:37591997:T Q263K missense_variant 0.83 0
14:37591390:T S465Y missense_variant 0.83 0
14:37591390:C S465C missense_variant 0.83 0
14:37591390:A S465F missense_variant 0.83 0
14:37591997:C Q263E missense_variant 0.83 0
14:37591547:C H413D missense_variant 0.83 0
14:37591547:A H413Y missense_variant 0.83 0
14:37592455:A P110L missense_variant 0.83 0
14:37592456:T P110T missense_variant 0.83 0
14:37592456:C P110A missense_variant 0.83 0
14:37592456:A P110S missense_variant 0.83 0
14:37591547:T H413N missense_variant 0.83 0
14:37592455:T P110Q missense_variant 0.83 0
14:37592455:C P110R missense_variant 0.83 0
14:37592515:C A90G missense_variant 0.83 0
14:37592515:T A90E missense_variant 0.83 0
14:37592515:A A90V missense_variant 0.83 0
14:37591610:C P392A missense_variant 0.83 0
14:37591610:A P392S missense_variant 0.83 0
14:37591610:T P392T missense_variant 0.83 0
14:37591592:T H398N missense_variant 0.83 0
14:37591592:C H398D missense_variant 0.83 0
14:37591592:A H398Y missense_variant 0.83 0
14:37591589:T P399T missense_variant 0.83 0
14:37591589:C P399A missense_variant 0.83 0
14:37592605:T T60N missense_variant 0.83 0
14:37592605:C T60S missense_variant 0.83 0
14:37592605:A T60I missense_variant 0.83 0
14:37591589:A P399S missense_variant 0.83 0
14:37591553:C Q411E missense_variant 0.83 0
14:37591553:T Q411K missense_variant 0.83 0
14:37591561:A S408F missense_variant 0.83 0
14:37591561:C S408C missense_variant 0.83 0
14:37591528:T A419E missense_variant 0.83 0
14:37591528:C A419G missense_variant 0.83 0
14:37591528:A A419V missense_variant 0.83 0
14:37592701:T S28Y missense_variant 0.83 0
14:37592701:C S28C missense_variant 0.83 0
14:37592701:A S28F missense_variant 0.83 0
14:37591561:T S408Y missense_variant 0.83 0
14:37592597:C S63A missense_variant 0.83 0
14:37592593:C F64C missense_variant 0.83 0
14:37592593:G F64S missense_variant 0.83 0
14:37592593:T F64Y missense_variant 0.83 0
14:37592597:G S63P missense_variant 0.83 0
14:37592597:T S63T missense_variant 0.83 0
14:37591415:A P457S missense_variant 0.83 0
14:37591415:C P457A missense_variant 0.83 0
14:37591415:T P457T missense_variant 0.83 0
14:37591369:T S472Y missense_variant 0.83 0
14:37591607:A H393Y missense_variant 0.83 0
14:37591369:C S472C missense_variant 0.83 0
14:37591369:A S472F missense_variant 0.83 0
14:37591607:C H393D missense_variant 0.83 0
14:37591607:T H393N missense_variant 0.83 0
14:37591900:G K295T missense_variant 0.83 0
14:37591900:A K295M missense_variant 0.83 0
14:37591900:C K295R missense_variant 0.83 0
14:37594945:A H10Y missense_variant 0.83 0
14:37594945:T H10N missense_variant 0.83 0
14:37594945:C H10D missense_variant 0.83 0
14:37594903:T E24K missense_variant 0.82 0
14:37594903:G E24Q missense_variant 0.82 0
14:37592187:A W199C missense_variant 0.81 0
14:37592187:G W199C missense_variant 0.81 0
14:37592222:G S188R missense_variant 0.81 0
14:37592222:A S188C missense_variant 0.81 0
14:37592222:C S188G missense_variant 0.81 0
14:37592467:C T106R missense_variant 0.81 0
14:37592467:A T106M missense_variant 0.81 0
14:37592467:T T106K missense_variant 0.81 0
14:37591773:T H337Q missense_variant 0.81 0
14:37592486:G G100R missense_variant 0.81 0
14:37592486:T G100S missense_variant 0.81 0
14:37592486:A G100C missense_variant 0.81 0
14:37591773:C H337Q missense_variant 0.81 0
14:37592188:G W199S missense_variant 0.81 0
14:37592188:A W199L missense_variant 0.81 0
14:37592625:G M53I missense_variant 0.81 0
14:37592625:A M53I missense_variant 0.81 0
14:37592625:T M53I missense_variant 0.81 0
14:37591391:C S465A missense_variant 0.80 0
14:37592688:T S32R missense_variant 0.80 0
14:37592688:C S32R missense_variant 0.80 0
14:37591391:G S465P missense_variant 0.80 0
14:37591391:T S465T missense_variant 0.80 0
14:37592609:G M59L missense_variant 0.80 0
14:37591580:A I402F missense_variant 0.80 0
14:37591580:C I402V missense_variant 0.80 0
14:37591580:G I402L missense_variant 0.80 0
14:37592609:C M59V missense_variant 0.80 0
14:37592609:A M59L missense_variant 0.80 0
14:37592373:C C137W missense_variant 0.80 0
14:37592033:G G251R missense_variant 0.80 0
14:37592033:A G251C missense_variant 0.80 0
14:37592033:T G251S missense_variant 0.80 0
14:37592479:C T102R missense_variant 0.79 0
14:37592479:T T102K missense_variant 0.79 0
14:37591558:C S409W missense_variant 0.79 0
14:37591558:A S409L missense_variant 0.79 0
14:37592479:A T102M missense_variant 0.79 0
14:37592076:T D236E missense_variant 0.79 0
14:37592076:C D236E missense_variant 0.79 0
14:37592191:C Q198R missense_variant 0.79 0
14:37592191:A Q198L missense_variant 0.79 0
14:37592191:G Q198P missense_variant 0.79 0
14:37592078:T D236N missense_variant 0.79 0
14:37592078:A D236Y missense_variant 0.79 0
14:37592078:G D236H missense_variant 0.79 0
14:37592650:A N45I missense_variant 0.79 0
14:37592650:C N45S missense_variant 0.79 0
14:37592650:G N45T missense_variant 0.79 0
14:37591376:A N470Y missense_variant 0.79 0
14:37591375:C N470S missense_variant 0.79 0
14:37591376:G N470H missense_variant 0.79 0
14:37591376:C N470D missense_variant 0.79 0
14:37591375:G N470T missense_variant 0.79 0
14:37591375:A N470I missense_variant 0.79 0
14:37592472:G M104I missense_variant 0.79 0
14:37592472:T M104I missense_variant 0.79 0
14:37591990:T R265H missense_variant 0.79 0
14:37591990:G R265P missense_variant 0.79 0
14:37591990:A R265L missense_variant 0.79 0
14:37592472:A M104I missense_variant 0.79 0
14:37591523:G E421Q missense_variant 0.78 0
14:37591523:T E421K missense_variant 0.78 0
14:37591474:T L437Q missense_variant 0.78 0
14:37591474:G L437P missense_variant 0.78 0
14:37591474:C L437R missense_variant 0.78 0
14:37591505:G S427P missense_variant 0.78 0
14:37591505:T S427T missense_variant 0.78 0
14:37591505:C S427A missense_variant 0.78 0
14:37591459:T A442D missense_variant 0.78 0
14:37591459:A A442V missense_variant 0.78 0
14:37591459:C A442G missense_variant 0.78 0
14:37592589:T N65K missense_variant 0.77 0
14:37592589:C N65K missense_variant 0.77 0
14:37591829:T Q319K missense_variant 0.77 0
14:37591829:C Q319E missense_variant 0.77 0
14:37592214:G M190I missense_variant 0.77 0
14:37592214:A M190I missense_variant 0.77 0
14:37592214:T M190I missense_variant 0.77 0
14:37591655:T H377N missense_variant 0.77 0
14:37591655:C H377D missense_variant 0.77 0
14:37591655:A H377Y missense_variant 0.77 0
14:37591504:C S427W missense_variant 0.77 0
14:37591504:A S427L missense_variant 0.77 0
14:37592032:A G251V missense_variant 0.77 0
14:37592032:G G251A missense_variant 0.77 0
14:37592032:T G251D missense_variant 0.77 0
14:37592039:G D249H missense_variant 0.76 0
14:37592039:T D249N missense_variant 0.76 0
14:37592039:A D249Y missense_variant 0.76 0
14:37592642:C M48V missense_variant 0.76 0
14:37592642:A M48L missense_variant 0.76 0
14:37592642:G M48L missense_variant 0.76 0
14:37592607:G M59I missense_variant 0.76 0
14:37592607:A M59I missense_variant 0.76 0
14:37592607:T M59I missense_variant 0.76 0
14:37592135:G S217P missense_variant 0.76 0
14:37592135:T S217T missense_variant 0.76 0
14:37592019:A E255D missense_variant 0.76 0
14:37592019:G E255D missense_variant 0.76 0
14:37591637:T E383K missense_variant 0.75 0
14:37591637:G E383Q missense_variant 0.75 0
14:37591606:G H393P missense_variant 0.75 0
14:37591606:C H393R missense_variant 0.75 0
14:37591606:A H393L missense_variant 0.75 0
14:37591408:C Y459C missense_variant 0.75 0
14:37591408:A Y459F missense_variant 0.75 0
14:37591619:C K389E missense_variant 0.75 0
14:37591619:G K389Q missense_variant 0.75 0
14:37591408:G Y459S missense_variant 0.75 0
14:37592087:T R233S missense_variant 0.74 0
14:37592087:C R233G missense_variant 0.74 0
14:37592087:A R233C missense_variant 0.74 0
14:37592370:A M138I missense_variant 0.73 0
14:37592370:T M138I missense_variant 0.73 0
14:37592370:G M138I missense_variant 0.73 0
14:37592644:A Y47F missense_variant 0.72 0
14:37592644:C Y47C missense_variant 0.72 0
14:37592644:G Y47S missense_variant 0.72 0
14:37592305:A K160M missense_variant 0.72 0
14:37592305:G K160T missense_variant 0.72 0
14:37592305:C K160R missense_variant 0.72 0
14:37591566:T M406I missense_variant 0.71 0
14:37591566:G M406I missense_variant 0.71 0
14:37591566:A M406I missense_variant 0.71 0
14:37591405:A Y460F missense_variant 0.71 0
14:37591405:G Y460S missense_variant 0.71 0
14:37591405:C Y460C missense_variant 0.71 0
14:37592291:C S165G missense_variant 0.71 0
14:37592291:G S165R missense_variant 0.71 0
14:37592291:A S165C missense_variant 0.71 0
14:37592300:T F162I missense_variant 0.71 0
14:37592306:G K160Q missense_variant 0.71 0
14:37592306:C K160E missense_variant 0.71 0
14:37592300:G F162L missense_variant 0.71 0
14:37592300:C F162V missense_variant 0.71 0
14:37591798:A A329V missense_variant 0.71 0
14:37591798:C A329G missense_variant 0.71 0
14:37591798:T A329D missense_variant 0.71 0
14:37592654:A M44L missense_variant 0.71 0
14:37592654:C M44V missense_variant 0.71 0
14:37592654:G M44L missense_variant 0.71 0
14:37591549:G Q412P missense_variant 0.70 0
14:37591549:A Q412L missense_variant 0.70 0
14:37591549:C Q412R missense_variant 0.70 0
14:37591513:C L424R missense_variant 0.70 0
14:37591513:T L424Q missense_variant 0.70 0
14:37591513:G L424P missense_variant 0.70 0
14:37591991:T R265S missense_variant 0.70 0
14:37591991:C R265G missense_variant 0.70 0
14:37591991:A R265C missense_variant 0.70 0
14:37592708:T Y26N missense_variant 0.70 0
14:37592708:C Y26D missense_variant 0.70 0
14:37592708:G Y26H missense_variant 0.70 0
14:37591594:C N397S missense_variant 0.70 0
14:37591594:G N397T missense_variant 0.70 0
14:37591594:A N397I missense_variant 0.70 0
14:37591574:A N404Y missense_variant 0.70 0
14:37591574:G N404H missense_variant 0.70 0
14:37591574:C N404D missense_variant 0.70 0
14:37591603:A Y394F missense_variant 0.70 0
14:37591603:G Y394S missense_variant 0.70 0
14:37591603:C Y394C missense_variant 0.70 0
14:37594925:C N16K missense_variant 0.70 0
14:37594925:T N16K missense_variant 0.70 0
14:37591372:T T471N missense_variant 0.70 0
14:37591372:C T471S missense_variant 0.70 0
14:37591372:A T471I missense_variant 0.70 0
14:37591414:C P457R missense_variant 0.70 0
14:37591414:A P457L missense_variant 0.70 0
14:37591414:T P457Q missense_variant 0.70 0
14:37591394:G Y464H missense_variant 0.69 0
14:37591394:T Y464N missense_variant 0.69 0
14:37591394:C Y464D missense_variant 0.69 0
14:37592554:G L77P missense_variant 0.69 0
14:37592554:C L77R missense_variant 0.69 0
14:37592554:T L77Q missense_variant 0.69 0
14:37592200:A E195V missense_variant 0.69 0
14:37592200:C E195G missense_variant 0.69 0
14:37592200:G E195A missense_variant 0.69 0
14:37592246:G T180P missense_variant 0.68 0
14:37592246:A T180S missense_variant 0.68 0
14:37592246:C T180A missense_variant 0.68 0
14:37591789:C P332R missense_variant 0.66 0
14:37591789:T P332H missense_variant 0.66 0
14:37591789:A P332L missense_variant 0.66 0
14:37592558:T G76S missense_variant 0.66 0
14:37591636:G E383A missense_variant 0.66 0
14:37591636:C E383G missense_variant 0.66 0
14:37591636:A E383V missense_variant 0.66 0
14:37592398:A P129L missense_variant 0.66 0
14:37592398:C P129R missense_variant 0.66 0
14:37592398:T P129H missense_variant 0.66 0
14:37592558:A G76C missense_variant 0.66 0
14:37592558:G G76R missense_variant 0.66 0
14:37592276:G K170Q missense_variant 0.66 0
14:37591430:C P452A missense_variant 0.66 0
14:37591430:T P452T missense_variant 0.66 0
14:37591430:A P452S missense_variant 0.66 0
14:37592276:C K170E missense_variant 0.66 0
14:37591531:C K418R missense_variant 0.66 0
14:37591531:G K418T missense_variant 0.66 0
14:37591531:A K418M missense_variant 0.66 0
14:37591536:T D416E missense_variant 0.66 0
14:37591536:C D416E missense_variant 0.66 0
14:37591403:C Q461E missense_variant 0.65 0
14:37591403:T Q461K missense_variant 0.65 0
14:37592687:G N33H missense_variant 0.64 0
14:37592687:C N33D missense_variant 0.64 0
14:37592687:A N33Y missense_variant 0.64 0
14:37591532:C K418E missense_variant 0.64 0
14:37591532:G K418Q missense_variant 0.64 0
14:37592531:C M85V missense_variant 0.64 0
14:37592531:G M85L missense_variant 0.64 0
14:37592531:A M85L missense_variant 0.64 0
14:37592312:A D158Y missense_variant 0.64 0
14:37592312:T D158N missense_variant 0.64 0
14:37592312:G D158H missense_variant 0.64 0
14:37591510:C Q425R missense_variant 0.64 0
14:37591510:G Q425P missense_variant 0.64 0
14:37591510:A Q425L missense_variant 0.64 0
14:37591778:A D336Y missense_variant 0.64 0
14:37591778:T D336N missense_variant 0.64 0
14:37591778:G D336H missense_variant 0.64 0
14:37592359:T A142E missense_variant 0.64 0
14:37592359:A A142V missense_variant 0.64 0
14:37592359:C A142G missense_variant 0.64 0
14:37591393:A Y464F missense_variant 0.63 0
14:37591393:G Y464S missense_variant 0.63 0
14:37591393:C Y464C missense_variant 0.63 0
14:37592326:C A153G missense_variant 0.63 0
14:37592326:A A153V missense_variant 0.63 0
14:37592326:T A153E missense_variant 0.63 0
14:37592207:C L193V missense_variant 0.62 0
14:37592207:T L193M missense_variant 0.62 0
14:37591838:G K316Q missense_variant 0.61 0
14:37591838:C K316E missense_variant 0.61 0
14:37591397:G V463L missense_variant 0.60 0
14:37591397:A V463L missense_variant 0.60 0
14:37591468:T L439Q missense_variant 0.60 0
14:37591468:G L439P missense_variant 0.60 0
14:37591397:T V463M missense_variant 0.60 0
14:37591468:C L439R missense_variant 0.60 0
14:37592134:T S217Y missense_variant 0.60 0
14:37592134:A S217F missense_variant 0.60 0
14:37592134:C S217C missense_variant 0.60 0
14:37592177:C L203V missense_variant 0.60 0
14:37592177:A L203F missense_variant 0.60 0
14:37592177:T L203I missense_variant 0.60 0
14:37592120:C L222V missense_variant 0.59 0
14:37592120:T L222M missense_variant 0.59 0
14:37592662:C M41R missense_variant 0.59 0
14:37592662:T M41K missense_variant 0.59 0
14:37592662:G M41T missense_variant 0.59 0
14:37591981:G C268S missense_variant 0.59 0
14:37591736:G K350Q missense_variant 0.59 0
14:37591981:A C268F missense_variant 0.59 0
14:37591736:C K350E missense_variant 0.59 0
14:37592147:T R213S missense_variant 0.59 0
14:37592147:C R213G missense_variant 0.59 0
14:37592147:A R213C missense_variant 0.59 0
14:37592342:C L148V missense_variant 0.58 0
14:37592342:T L148M missense_variant 0.58 0
14:37591858:G L309P missense_variant 0.58 0
14:37591858:C L309R missense_variant 0.58 0
14:37591858:T L309H missense_variant 0.58 0
14:37591546:A H413L missense_variant 0.57 0
14:37591546:G H413P missense_variant 0.57 0
14:37591546:C H413R missense_variant 0.57 0
14:37592377:C P136R missense_variant 0.57 0
14:37592377:A P136L missense_variant 0.57 0
14:37592377:T P136Q missense_variant 0.57 0
14:37591790:A P332S missense_variant 0.56 0
14:37591790:T P332T missense_variant 0.56 0
14:37591790:C P332A missense_variant 0.56 0
14:37592366:T P140T missense_variant 0.56 0
14:37592366:C P140A missense_variant 0.56 0
14:37592366:A P140S missense_variant 0.56 0
14:37592016:C N256K missense_variant 0.56 0
14:37591427:C S453A missense_variant 0.55 0
14:37591427:T S453T missense_variant 0.55 0
14:37591427:G S453P missense_variant 0.55 0
14:37591661:C P375A missense_variant 0.55 0
14:37591661:T P375T missense_variant 0.55 0
14:37591661:A P375S missense_variant 0.55 0
14:37592416:T S123Y missense_variant 0.55 0
14:37592416:C S123C missense_variant 0.55 0
14:37592416:A S123F missense_variant 0.55 0
14:37592124:T H220Q missense_variant 0.55 0
14:37591579:C I402S missense_variant 0.54 0
14:37591540:T L415Q missense_variant 0.54 0
14:37591540:C L415R missense_variant 0.54 0
14:37591540:G L415P missense_variant 0.54 0
14:37591579:T I402N missense_variant 0.54 0
14:37591579:G I402T missense_variant 0.54 0
14:37591684:T L367Q missense_variant 0.54 0
14:37592500:A S95I missense_variant 0.54 0
14:37592695:A P30L missense_variant 0.54 0
14:37592500:T S95N missense_variant 0.54 0
14:37592695:C P30R missense_variant 0.54 0
14:37592695:T P30Q missense_variant 0.54 0
14:37591684:G L367P missense_variant 0.54 0
14:37594912:A D21Y missense_variant 0.54 0
14:37594912:G D21H missense_variant 0.54 0
14:37594912:T D21N missense_variant 0.54 0
14:37591684:C L367R missense_variant 0.54 0
14:37592010:C C258W missense_variant 0.54 0
14:37591585:G F400S missense_variant 0.54 0
14:37591585:T F400Y missense_variant 0.54 0
14:37591585:C F400C missense_variant 0.54 0
14:37591586:T F400I missense_variant 0.54 0
14:37591586:G F400L missense_variant 0.54 0
14:37591534:G F417S missense_variant 0.54 0
14:37592578:A A69V missense_variant 0.54 0
14:37591534:C F417C missense_variant 0.54 0
14:37591586:C F400V missense_variant 0.54 0
14:37592578:T A69D missense_variant 0.54 0
14:37592578:C A69G missense_variant 0.54 0
14:37591534:T F417Y missense_variant 0.54 0
14:37592640:A M48I missense_variant 0.54 0
14:37591402:C Q461R missense_variant 0.54 0
14:37591402:A Q461L missense_variant 0.54 0
14:37592640:T M48I missense_variant 0.54 0
14:37591402:G Q461P missense_variant 0.54 0
14:37592640:G M48I missense_variant 0.54 0
14:37592051:G T245P missense_variant 0.54 0
14:37592051:C T245A missense_variant 0.54 0
14:37592051:A T245S missense_variant 0.54 0
14:37591555:G E410A missense_variant 0.54 0
14:37591555:C E410G missense_variant 0.54 0
14:37591555:A E410V missense_variant 0.54 0
14:37592136:C N216K missense_variant 0.53 0
14:37592136:T N216K missense_variant 0.53 0
14:37591756:T T343K missense_variant 0.53 0
14:37591556:T E410K missense_variant 0.53 0
14:37591701:C S361R missense_variant 0.53 0
14:37591756:A T343I missense_variant 0.53 0
14:37591701:T S361R missense_variant 0.53 0
14:37591556:G E410Q missense_variant 0.53 0
14:37592379:T N135K missense_variant 0.53 0
14:37592379:C N135K missense_variant 0.53 0
14:37591756:C T343R missense_variant 0.53 0
14:37592351:A P145S missense_variant 0.53 0
14:37592534:A G84C missense_variant 0.53 0
14:37592534:G G84R missense_variant 0.53 0
14:37592534:T G84S missense_variant 0.53 0
14:37592351:C P145A missense_variant 0.53 0
14:37592351:T P145T missense_variant 0.53 0
14:37591465:T G440D missense_variant 0.53 0
14:37591973:C Q271E missense_variant 0.53 0
14:37591465:A G440V missense_variant 0.53 0
14:37591973:T Q271K missense_variant 0.53 0
14:37591465:G G440A missense_variant 0.53 0
14:37594949:A E8D missense_variant 0.53 0
14:37594949:G E8D missense_variant 0.53 0
14:37592130:C I218M missense_variant 0.53 0
14:37592426:T Q120K missense_variant 0.53 0
14:37591734:A K350N missense_variant 0.53 0
14:37591734:G K350N missense_variant 0.53 0
14:37592426:C Q120E missense_variant 0.53 0
14:37592247:C I179M missense_variant 0.53 0
14:37591651:A G378V missense_variant 0.52 0
14:37591651:T G378D missense_variant 0.52 0
14:37591651:G G378A missense_variant 0.52 0
14:37591633:C S384C missense_variant 0.52 0
14:37591633:A S384F missense_variant 0.52 0
14:37591633:T S384Y missense_variant 0.52 0
14:37592566:C L73R missense_variant 0.52 0
14:37592566:G L73P missense_variant 0.52 0
14:37592566:T L73Q missense_variant 0.52 0
14:37591787:C Q333E missense_variant 0.52 0
14:37591787:T Q333K missense_variant 0.52 0
14:37591378:C L469R missense_variant 0.52 0
14:37591378:T L469Q missense_variant 0.52 0
14:37591378:G L469P missense_variant 0.52 0
14:37591381:T V468D missense_variant 0.52 0
14:37591381:C V468G missense_variant 0.52 0
14:37591381:G V468A missense_variant 0.52 0
14:37592362:C M141R missense_variant 0.52 0
14:37592362:G M141T missense_variant 0.52 0
14:37592362:T M141K missense_variant 0.52 0
14:37592636:A M50L missense_variant 0.52 0
14:37592636:C M50V missense_variant 0.52 0
14:37592636:G M50L missense_variant 0.52 0
14:37592357:C Y143D missense_variant 0.52 0
14:37592357:G Y143H missense_variant 0.52 0
14:37592357:T Y143N missense_variant 0.52 0
14:37591982:G C268R missense_variant 0.52 0
14:37591982:T C268S missense_variant 0.52 0
14:37591982:C C268G missense_variant 0.52 0
14:37592682:T M34I missense_variant 0.51 0
14:37592682:A M34I missense_variant 0.51 0
14:37592682:G M34I missense_variant 0.51 0
14:37591768:A G339V missense_variant 0.51 0
14:37591768:T G339E missense_variant 0.51 0
14:37591768:G G339A missense_variant 0.51 0
14:37592431:T A118E missense_variant 0.51 0
14:37592431:A A118V missense_variant 0.51 0
14:37592431:C A118G missense_variant 0.51 0
14:37591545:T H413Q missense_variant 0.51 0
14:37591545:C H413Q missense_variant 0.51 0
14:37594962:T T4N missense_variant 0.51 0
14:37594962:A T4I missense_variant 0.51 0
14:37594962:C T4S missense_variant 0.51 0
14:37594917:G Y19S missense_variant 0.51 0
14:37594917:A Y19F missense_variant 0.51 0
14:37594957:G K6Q missense_variant 0.51 0
14:37594957:C K6E missense_variant 0.51 0
14:37594956:G K6T missense_variant 0.51 0
14:37594956:C K6R missense_variant 0.51 0
14:37594956:A K6M missense_variant 0.51 0
14:37594954:G M7L missense_variant 0.51 0
14:37594954:C M7V missense_variant 0.51 0
14:37594954:A M7L missense_variant 0.51 0
14:37594950:G E8A missense_variant 0.51 0
14:37594950:C E8G missense_variant 0.51 0
14:37594950:A E8V missense_variant 0.51 0
14:37594944:G H10P missense_variant 0.51 0
14:37594944:C H10R missense_variant 0.51 0
14:37594944:A H10L missense_variant 0.51 0
14:37594941:G E11A missense_variant 0.51 0
14:37594941:C E11G missense_variant 0.51 0
14:37594941:A E11V missense_variant 0.51 0
14:37594932:G D14A missense_variant 0.51 0
14:37594932:C D14G missense_variant 0.51 0
14:37594932:A D14V missense_variant 0.51 0
14:37594927:G N16H missense_variant 0.51 0
14:37594927:C N16D missense_variant 0.51 0
14:37594927:A N16Y missense_variant 0.51 0
14:37594917:C Y19C missense_variant 0.51 0
14:37592696:T P30T missense_variant 0.51 0
14:37592696:C P30A missense_variant 0.51 0
14:37592696:A P30S missense_variant 0.51 0
14:37592587:G M66T missense_variant 0.51 0
14:37592587:C M66R missense_variant 0.51 0
14:37592587:T M66K missense_variant 0.51 0
14:37592679:C N35K missense_variant 0.51 0
14:37592679:T N35K missense_variant 0.51 0
14:37592497:C M96R missense_variant 0.51 0
14:37591658:G A376P missense_variant 0.51 0
14:37591658:T A376T missense_variant 0.51 0
14:37591658:A A376S missense_variant 0.51 0
14:37592497:G M96T missense_variant 0.51 0
14:37592497:T M96K missense_variant 0.51 0
14:37591526:T Y420N missense_variant 0.51 0
14:37591526:G Y420H missense_variant 0.51 0
14:37591526:C Y420D missense_variant 0.51 0
14:37592683:C M34R missense_variant 0.51 0
14:37592683:G M34T missense_variant 0.51 0
14:37592683:T M34K missense_variant 0.51 0
14:37592335:G R150P missense_variant 0.51 0
14:37592335:A R150L missense_variant 0.51 0
14:37592335:T R150H missense_variant 0.51 0
14:37591699:T S362Y missense_variant 0.50 0
14:37591699:C S362C missense_variant 0.50 0
14:37591699:A S362F missense_variant 0.50 0
14:37591499:C Y429D missense_variant 0.50 0
14:37591499:T Y429N missense_variant 0.50 0
14:37591499:G Y429H missense_variant 0.50 0
14:37591583:T S401T missense_variant 0.50 0
14:37591570:C L405R missense_variant 0.50 0
14:37591567:G M406T missense_variant 0.50 0
14:37591567:C M406R missense_variant 0.50 0
14:37591508:G Y426H missense_variant 0.50 0
14:37591570:T L405H missense_variant 0.50 0
14:37591570:G L405P missense_variant 0.50 0
14:37591583:C S401A missense_variant 0.50 0
14:37591583:G S401P missense_variant 0.50 0
14:37591567:T M406K missense_variant 0.50 0
14:37591508:C Y426D missense_variant 0.50 0
14:37591508:T Y426N missense_variant 0.50 0
14:37591898:T D296N missense_variant 0.50 0
14:37591898:A D296Y missense_variant 0.50 0
14:37591898:G D296H missense_variant 0.50 0
14:37592545:G G80A missense_variant 0.50 0
14:37592545:A G80V missense_variant 0.50 0
14:37592545:T G80D missense_variant 0.50 0
14:37592661:G M41I missense_variant 0.50 0
14:37592661:A M41I missense_variant 0.50 0
14:37592661:T M41I missense_variant 0.50 0
14:37591751:T G345S missense_variant 0.50 0
14:37591751:G G345R missense_variant 0.50 0
14:37591751:A G345C missense_variant 0.50 0
14:37592612:G N58H missense_variant 0.50 0
14:37592612:C N58D missense_variant 0.50 0
14:37592612:A N58Y missense_variant 0.50 0
14:37591741:G E348A missense_variant 0.50 0
14:37591741:C E348G missense_variant 0.50 0
14:37591741:A E348V missense_variant 0.50 0
14:37591735:C K350R missense_variant 0.50 0
14:37591735:A K350M missense_variant 0.50 0
14:37591735:G K350T missense_variant 0.50 0
14:37591825:T L320Q missense_variant 0.50 0
14:37591825:C L320R missense_variant 0.50 0
14:37591379:T L469I missense_variant 0.50 0
14:37591379:C L469V missense_variant 0.50 0
14:37591825:G L320P missense_variant 0.50 0
14:37591572:C N404K missense_variant 0.50 0
14:37591572:T N404K missense_variant 0.50 0
14:37592671:T L38Q missense_variant 0.50 0
14:37592671:C L38R missense_variant 0.50 0
14:37592671:G L38P missense_variant 0.50 0
14:37591598:G F396L missense_variant 0.50 0
14:37591598:T F396I missense_variant 0.50 0
14:37591598:C F396V missense_variant 0.50 0
14:37591597:T F396Y missense_variant 0.50 0
14:37591597:G F396S missense_variant 0.50 0
14:37591597:C F396C missense_variant 0.50 0
In silico saturation mutagenesis
Alt text Show figure caption
Cancer type Selected cancer type Mutational discovery Index Feature Complexity
(PRAD) Prostate adenocarcinoma PRAD 0.62 0.17