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Note: You're navigating the results of models obtained with IntOGen (2020). A new boostDM version is available here.
HLA-A DLBCL ×
Select a mutation to see further information
Mutation AA change Consequence type BoostDM score IntOGen frequency
6:29942908:A W75* stop_gained 0.99 2
6:29942832:T G50V missense_variant 0.98 2
6:29943414:A A164T missense_variant 0.98 2
6:29943348:G Y142D missense_variant 0.98 2
6:29943295:A G124D missense_variant 0.98 2
6:29943534:T Q204* stop_gained 0.81 2
6:29944225:A W241* stop_gained 1.00 1
6:29943014:T Q111* stop_gained 0.98 1
6:29943415:T A164V missense_variant 0.98 1
6:29943497:A W191* stop_gained 0.98 1
6:29944253:C D251H missense_variant 0.97 1
6:29943459:T Q179* stop_gained 0.96 1
6:29942915:T Q78* stop_gained 0.96 1
6:29943525:T E201* stop_gained 0.96 1
6:29942572:T R7* stop_gained 0.87 1
6:29942849:T Q56* stop_gained 0.85 1
6:29943542:T T206T splice_region_variant 0.83 1
6:29944246:C Q248H missense_variant 0.68 1
6:29944306:A W268* stop_gained 1.00 0
6:29943282:T Q120* stop_gained 1.00 0
6:29943438:T E172* stop_gained 1.00 0
6:29943437:A W171* stop_gained 1.00 0
6:29944224:A W241* stop_gained 1.00 0
6:29942935:A W84* stop_gained 1.00 0
6:29944268:T E256* stop_gained 1.00 0
6:29942810:T E43* stop_gained 0.99 0
6:29944201:G Y233* stop_gained 0.99 0
6:29944201:A Y233* stop_gained 0.99 0
6:29943504:T R194* stop_gained 0.99 0
6:29943365:A Y147* stop_gained 0.99 0
6:29943365:G Y147* stop_gained 0.99 0
6:29943010:A Y109* stop_gained 0.99 0
6:29943010:G Y109* stop_gained 0.99 0
6:29943509:G Y195* stop_gained 0.99 0
6:29943509:A Y195* stop_gained 0.99 0
6:29944298:T Q266* stop_gained 0.99 0
6:29944250:T Q250* stop_gained 0.99 0
6:29943395:A W157* stop_gained 0.99 0
6:29942934:A W84* stop_gained 0.99 0
6:29944305:A W268* stop_gained 0.99 0
6:29943532:G L203R missense_variant 0.98 0
6:29943415:G A164G missense_variant 0.98 0
6:29943415:A A164D missense_variant 0.98 0
6:29943532:A L203Q missense_variant 0.98 0
6:29943532:C L203P missense_variant 0.98 0
6:29943511:G L196R missense_variant 0.98 0
6:29943511:C L196P missense_variant 0.98 0
6:29943511:A L196Q missense_variant 0.98 0
6:29944362:C H287P missense_variant 0.98 0
6:29944362:T H287L missense_variant 0.98 0
6:29944362:G H287R missense_variant 0.98 0
6:29942838:C V52A missense_variant 0.98 0
6:29942838:A V52E missense_variant 0.98 0
6:29942838:G V52G missense_variant 0.98 0
6:29942861:C F60L missense_variant 0.98 0
6:29942861:A F60I missense_variant 0.98 0
6:29942861:G F60V missense_variant 0.98 0
6:29943376:T N151I missense_variant 0.98 0
6:29943376:G N151S missense_variant 0.98 0
6:29943376:C N151T missense_variant 0.98 0
6:29942832:A G50D missense_variant 0.98 0
6:29943026:T G115C missense_variant 0.98 0
6:29943026:A G115S missense_variant 0.98 0
6:29943026:C G115R missense_variant 0.98 0
6:29942832:C G50A missense_variant 0.98 0
6:29942762:T H27Y missense_variant 0.98 0
6:29942762:A H27N missense_variant 0.98 0
6:29942762:G H27D missense_variant 0.98 0
6:29943013:G N110K missense_variant 0.98 0
6:29943013:A N110K missense_variant 0.98 0
6:29944395:A W298* stop_gained 0.98 0
6:29943283:C Q120P missense_variant 0.98 0
6:29944225:T W241C missense_variant 0.98 0
6:29944225:C W241C missense_variant 0.98 0
6:29943283:G Q120R missense_variant 0.98 0
6:29943283:T Q120L missense_variant 0.98 0
6:29943414:C A164P missense_variant 0.98 0
6:29943414:T A164S missense_variant 0.98 0
6:29944208:T E236* stop_gained 0.98 0
6:29944299:T Q266L missense_variant 0.98 0
6:29944299:G Q266R missense_variant 0.98 0
6:29944299:C Q266P missense_variant 0.98 0
6:29943351:C D143H missense_variant 0.98 0
6:29943351:A D143N missense_variant 0.98 0
6:29943351:T D143Y missense_variant 0.98 0
6:29944368:C G289A missense_variant 0.98 0
6:29944368:T G289V missense_variant 0.98 0
6:29944368:A G289D missense_variant 0.98 0
6:29943011:C N110H missense_variant 0.98 0
6:29943011:G N110D missense_variant 0.98 0
6:29943011:T N110Y missense_variant 0.98 0
6:29944356:A V285E missense_variant 0.98 0
6:29944356:G V285G missense_variant 0.98 0
6:29944356:C V285A missense_variant 0.98 0
6:29944343:G Y281D missense_variant 0.98 0
6:29944343:C Y281H missense_variant 0.98 0
6:29944343:A Y281N missense_variant 0.98 0
6:29944349:G C283G missense_variant 0.98 0
6:29944349:A C283S missense_variant 0.98 0
6:29944349:C C283R missense_variant 0.98 0
6:29944187:C A229P missense_variant 0.98 0
6:29944187:T A229S missense_variant 0.98 0
6:29944187:A A229T missense_variant 0.98 0
6:29944371:G L290R missense_variant 0.98 0
6:29944371:C L290P missense_variant 0.98 0
6:29944371:A L290Q missense_variant 0.98 0
6:29944224:C W241S missense_variant 0.98 0
6:29944224:T W241L missense_variant 0.98 0
6:29943399:C A159P missense_variant 0.98 0
6:29943399:A A159T missense_variant 0.98 0
6:29943399:T A159S missense_variant 0.98 0
6:29944295:A F265I missense_variant 0.98 0
6:29944295:G F265V missense_variant 0.98 0
6:29944218:A L239Q missense_variant 0.98 0
6:29944218:C L239P missense_variant 0.98 0
6:29944218:G L239R missense_variant 0.98 0
6:29944295:C F265L missense_variant 0.98 0
6:29944233:C D244A missense_variant 0.98 0
6:29944233:T D244V missense_variant 0.98 0
6:29944233:G D244G missense_variant 0.98 0
6:29943472:T Y183F missense_variant 0.98 0
6:29943472:G Y183C missense_variant 0.98 0
6:29943472:C Y183S missense_variant 0.98 0
6:29944223:G W241G missense_variant 0.98 0
6:29944223:C W241R missense_variant 0.98 0
6:29944223:A W241R missense_variant 0.98 0
6:29943402:T A160S missense_variant 0.98 0
6:29943402:A A160T missense_variant 0.98 0
6:29943402:C A160P missense_variant 0.98 0
6:29944290:A G263E missense_variant 0.98 0
6:29944290:T G263V missense_variant 0.98 0
6:29944290:C G263A missense_variant 0.98 0
6:29944297:G F265L missense_variant 0.98 0
6:29944297:A F265L missense_variant 0.98 0
6:29944193:A G231S missense_variant 0.98 0
6:29944193:C G231R missense_variant 0.98 0
6:29944361:T H287Y missense_variant 0.98 0
6:29944361:G H287D missense_variant 0.98 0
6:29944361:A H287N missense_variant 0.98 0
6:29944193:T G231C missense_variant 0.98 0
6:29942840:T D53Y missense_variant 0.98 0
6:29942840:A D53N missense_variant 0.98 0
6:29942840:C D53H missense_variant 0.98 0
6:29942935:C W84C missense_variant 0.98 0
6:29942935:T W84C missense_variant 0.98 0
6:29943313:T D130V missense_variant 0.98 0
6:29943439:G E172G missense_variant 0.98 0
6:29943439:T E172V missense_variant 0.98 0
6:29943313:C D130A missense_variant 0.98 0
6:29943313:G D130G missense_variant 0.98 0
6:29943439:C E172A missense_variant 0.98 0
6:29944396:A W298* stop_gained 0.98 0
6:29943437:C W171C missense_variant 0.98 0
6:29943437:T W171C missense_variant 0.98 0
6:29943330:A G136R missense_variant 0.98 0
6:29943330:T G136W missense_variant 0.98 0
6:29943330:C G136R missense_variant 0.98 0
6:29943487:C C188S missense_variant 0.98 0
6:29944235:C G245R missense_variant 0.98 0
6:29943367:C I148T missense_variant 0.98 0
6:29944235:T G245W missense_variant 0.98 0
6:29944287:C D262A missense_variant 0.98 0
6:29944287:G D262G missense_variant 0.98 0
6:29944287:T D262V missense_variant 0.98 0
6:29943520:T G199V missense_variant 0.98 0
6:29943520:C G199A missense_variant 0.98 0
6:29943520:A G199E missense_variant 0.98 0
6:29943273:A H117N missense_variant 0.98 0
6:29943273:G H117D missense_variant 0.98 0
6:29943273:T H117Y missense_variant 0.98 0
6:29943274:C H117P missense_variant 0.98 0
6:29943274:G H117R missense_variant 0.98 0
6:29943274:T H117L missense_variant 0.98 0
6:29944350:A C283Y missense_variant 0.98 0
6:29944350:C C283S missense_variant 0.98 0
6:29943499:G L192R missense_variant 0.98 0
6:29944350:T C283F missense_variant 0.98 0
6:29944355:A V285M missense_variant 0.98 0
6:29943367:G I148S missense_variant 0.98 0
6:29943499:C L192P missense_variant 0.98 0
6:29943499:A L192H missense_variant 0.98 0
6:29944355:C V285L missense_variant 0.98 0
6:29943487:T C188F missense_variant 0.98 0
6:29943367:A I148N missense_variant 0.98 0
6:29943294:A G124S missense_variant 0.98 0
6:29943294:C G124R missense_variant 0.98 0
6:29943294:T G124C missense_variant 0.98 0
6:29944355:T V285L missense_variant 0.98 0
6:29943295:C G124A missense_variant 0.98 0
6:29943295:T G124V missense_variant 0.98 0
6:29943297:A C125S missense_variant 0.98 0
6:29943297:C C125R missense_variant 0.98 0
6:29943297:G C125G missense_variant 0.98 0
6:29943298:A C125Y missense_variant 0.98 0
6:29943298:C C125S missense_variant 0.98 0
6:29943298:T C125F missense_variant 0.98 0
6:29943487:A C188Y missense_variant 0.98 0
6:29943486:G C188G missense_variant 0.98 0
6:29943486:C C188R missense_variant 0.98 0
6:29943486:A C188S missense_variant 0.98 0
6:29943424:T T167I missense_variant 0.98 0
6:29943424:G T167S missense_variant 0.98 0
6:29943424:A T167N missense_variant 0.98 0
6:29943348:A Y142N missense_variant 0.98 0
6:29943348:C Y142H missense_variant 0.98 0
6:29943352:C D143A missense_variant 0.98 0
6:29943352:G D143G missense_variant 0.98 0
6:29943352:T D143V missense_variant 0.98 0
6:29943361:C D146A missense_variant 0.98 0
6:29943361:G D146G missense_variant 0.98 0
6:29943361:T D146V missense_variant 0.98 0
6:29944235:A G245R missense_variant 0.98 0
6:29943360:A D146N missense_variant 0.98 0
6:29943360:C D146H missense_variant 0.98 0
6:29943360:T D146Y missense_variant 0.98 0
6:29943354:C G144R missense_variant 0.98 0
6:29943354:T G144C missense_variant 0.98 0
6:29943355:A G144D missense_variant 0.98 0
6:29943355:C G144A missense_variant 0.98 0
6:29943355:T G144V missense_variant 0.98 0
6:29943284:C Q120H missense_variant 0.98 0
6:29943284:T Q120H missense_variant 0.98 0
6:29943354:A G144S missense_variant 0.98 0
6:29944196:C F232L missense_variant 0.98 0
6:29944202:A P234T missense_variant 0.98 0
6:29944202:G P234A missense_variant 0.98 0
6:29944202:T P234S missense_variant 0.98 0
6:29944197:A F232Y missense_variant 0.98 0
6:29944203:A P234H missense_variant 0.98 0
6:29944203:T P234L missense_variant 0.98 0
6:29944203:G P234R missense_variant 0.98 0
6:29944197:C F232S missense_variant 0.98 0
6:29944197:G F232C missense_variant 0.98 0
6:29944196:A F232I missense_variant 0.98 0
6:29944196:G F232V missense_variant 0.98 0
6:29943478:C D185A missense_variant 0.98 0
6:29943478:T D185V missense_variant 0.98 0
6:29943478:G D185G missense_variant 0.98 0
6:29944344:G Y281C missense_variant 0.98 0
6:29944200:C Y233S missense_variant 0.98 0
6:29944200:G Y233C missense_variant 0.98 0
6:29944200:T Y233F missense_variant 0.98 0
6:29944344:C Y281S missense_variant 0.98 0
6:29944344:T Y281F missense_variant 0.98 0
6:29944286:C D262H missense_variant 0.97 0
6:29944286:T D262Y missense_variant 0.97 0
6:29944286:A D262N missense_variant 0.97 0
6:29944277:A P259T missense_variant 0.97 0
6:29944277:T P259S missense_variant 0.97 0
6:29944277:G P259A missense_variant 0.97 0
6:29942831:A G50S missense_variant 0.97 0
6:29942831:T G50C missense_variant 0.97 0
6:29942831:C G50R missense_variant 0.97 0
6:29944253:A D251N missense_variant 0.97 0
6:29944253:T D251Y missense_variant 0.97 0
6:29943519:A G199R missense_variant 0.97 0
6:29943519:T G199W missense_variant 0.97 0
6:29943519:C G199R missense_variant 0.97 0
6:29942841:T D53V missense_variant 0.97 0
6:29942841:G D53G missense_variant 0.97 0
6:29942841:C D53A missense_variant 0.97 0
6:29943282:A Q120K missense_variant 0.97 0
6:29943282:G Q120E missense_variant 0.97 0
6:29943475:A L184Q missense_variant 0.97 0
6:29943475:C L184P missense_variant 0.97 0
6:29943475:G L184R missense_variant 0.97 0
6:29944306:C W268C missense_variant 0.97 0
6:29943017:G S112G missense_variant 0.97 0
6:29943017:C S112R missense_variant 0.97 0
6:29944306:T W268C missense_variant 0.97 0
6:29943017:T S112C missense_variant 0.97 0
6:29943471:G Y183D missense_variant 0.97 0
6:29943471:C Y183H missense_variant 0.97 0
6:29943471:A Y183N missense_variant 0.97 0
6:29943363:C Y147H missense_variant 0.97 0
6:29943363:G Y147D missense_variant 0.97 0
6:29943363:A Y147N missense_variant 0.97 0
6:29944182:C C227S missense_variant 0.97 0
6:29944182:T C227F missense_variant 0.97 0
6:29944182:A C227Y missense_variant 0.97 0
6:29942963:T Q94* stop_gained 0.96 0
6:29942942:T E87* stop_gained 0.96 0
6:29942939:T Q86* stop_gained 0.96 0
6:29943463:A L180* stop_gained 0.96 0
6:29943335:G Y137* stop_gained 0.96 0
6:29943335:A Y137* stop_gained 0.96 0
6:29943293:A Y123* stop_gained 0.96 0
6:29943293:G Y123* stop_gained 0.96 0
6:29943488:A C188* stop_gained 0.96 0
6:29942907:A W75* stop_gained 0.96 0
6:29942978:T R99* stop_gained 0.96 0
6:29943357:T K145* stop_gained 0.96 0
6:29942932:A Y83* stop_gained 0.96 0
6:29942932:G Y83* stop_gained 0.96 0
6:29944252:C Q250H missense_variant 0.96 0
6:29944252:T Q250H missense_variant 0.96 0
6:29943438:A E172K missense_variant 0.96 0
6:29943438:C E172Q missense_variant 0.96 0
6:29944340:T R280* stop_gained 0.96 0
6:29943299:A C125* stop_gained 0.96 0
6:29942912:T E77* stop_gained 0.96 0
6:29942969:T Q96* stop_gained 0.96 0
6:29944574:T G324* stop_gained 0.96 0
6:29943473:A Y183* stop_gained 0.96 0
6:29943473:G Y183* stop_gained 0.96 0
6:29944183:A C227* stop_gained 0.96 0
6:29943436:A W171* stop_gained 0.96 0
6:29943276:G T118A missense_variant 0.96 0
6:29943276:T T118S missense_variant 0.96 0
6:29943276:C T118P missense_variant 0.96 0
6:29943312:A D130N missense_variant 0.95 0
6:29943312:C D130H missense_variant 0.95 0
6:29943312:T D130Y missense_variant 0.95 0
6:29943007:A Y108* stop_gained 0.95 0
6:29943007:G Y108* stop_gained 0.95 0
6:29943465:T R181* stop_gained 0.95 0
6:29944328:T G276* stop_gained 0.95 0
6:29944268:A E256K missense_variant 0.95 0
6:29944268:C E256Q missense_variant 0.95 0
6:29944559:T G319* stop_gained 0.95 0
6:29944185:A W228* stop_gained 0.95 0
6:29943394:A W157* stop_gained 0.95 0
6:29943450:T E176* stop_gained 0.95 0
6:29944301:T K267* stop_gained 0.94 0
6:29943339:T Q139* stop_gained 0.94 0
6:29944289:T G263* stop_gained 0.94 0
6:29942918:T E79* stop_gained 0.94 0
6:29942927:T E82* stop_gained 0.94 0
6:29942967:G S95* stop_gained 0.93 0
6:29942967:A S95* stop_gained 0.93 0
6:29943426:T K168* stop_gained 0.93 0
6:29944358:T Q286* stop_gained 0.93 0
6:29944334:T E278* stop_gained 0.92 0
6:29944181:G C227G missense_variant 0.92 0
6:29944181:A C227S missense_variant 0.92 0
6:29944181:C C227R missense_variant 0.92 0
6:29944194:C G231A missense_variant 0.91 0
6:29944194:T G231V missense_variant 0.91 0
6:29943331:T G136V missense_variant 0.91 0
6:29943331:C G136A missense_variant 0.91 0
6:29943331:A G136E missense_variant 0.91 0
6:29944194:A G231D missense_variant 0.91 0
6:29944278:T P259L missense_variant 0.91 0
6:29944278:A P259H missense_variant 0.91 0
6:29944278:G P259R missense_variant 0.91 0
6:29944239:C E246A missense_variant 0.91 0
6:29944239:T E246V missense_variant 0.91 0
6:29944239:G E246G missense_variant 0.91 0
6:29944314:C V271A missense_variant 0.91 0
6:29943375:T N151Y missense_variant 0.91 0
6:29944314:G V271G missense_variant 0.91 0
6:29944314:A V271E missense_variant 0.91 0
6:29943375:G N151D missense_variant 0.91 0
6:29943375:C N151H missense_variant 0.91 0
6:29943393:A W157R missense_variant 0.90 0
6:29943393:G W157G missense_variant 0.90 0
6:29943373:C L150P missense_variant 0.90 0
6:29943373:G L150R missense_variant 0.90 0
6:29943373:A L150Q missense_variant 0.90 0
6:29943393:C W157R missense_variant 0.90 0
6:29943382:T D153V missense_variant 0.90 0
6:29943008:G Y109D missense_variant 0.90 0
6:29943382:G D153G missense_variant 0.90 0
6:29943382:C D153A missense_variant 0.90 0
6:29943008:C Y109H missense_variant 0.90 0
6:29943008:A Y109N missense_variant 0.90 0
6:29944270:T E256D missense_variant 0.90 0
6:29944270:C E256D missense_variant 0.90 0
6:29942810:A E43K missense_variant 0.90 0
6:29942810:C E43Q missense_variant 0.90 0
6:29942936:T D85Y missense_variant 0.90 0
6:29942936:A D85N missense_variant 0.90 0
6:29942936:C D85H missense_variant 0.90 0
6:29942884:T Q67H missense_variant 0.90 0
6:29942884:C Q67H missense_variant 0.90 0
6:29943316:T G131V missense_variant 0.90 0
6:29943316:C G131A missense_variant 0.90 0
6:29943316:A G131E missense_variant 0.90 0
6:29944292:C T264P missense_variant 0.90 0
6:29942988:G L102R missense_variant 0.90 0
6:29942988:C L102P missense_variant 0.90 0
6:29942988:A L102Q missense_variant 0.90 0
6:29944292:G T264A missense_variant 0.90 0
6:29944292:T T264S missense_variant 0.90 0
6:29943490:A V189E missense_variant 0.90 0
6:29943490:C V189A missense_variant 0.90 0
6:29943490:G V189G missense_variant 0.90 0
6:29942895:T P71L missense_variant 0.90 0
6:29942895:A P71Q missense_variant 0.90 0
6:29942895:G P71R missense_variant 0.90 0
6:29942799:G P39R missense_variant 0.90 0
6:29942799:T P39L missense_variant 0.90 0
6:29942799:A P39H missense_variant 0.90 0
6:29943304:A V127E missense_variant 0.90 0
6:29943304:G V127G missense_variant 0.90 0
6:29943304:C V127A missense_variant 0.90 0
6:29943301:C D126A missense_variant 0.90 0
6:29943301:T D126V missense_variant 0.90 0
6:29943301:G D126G missense_variant 0.90 0
6:29944307:C A269P missense_variant 0.90 0
6:29944307:A A269T missense_variant 0.90 0
6:29944307:T A269S missense_variant 0.90 0
6:29942933:C W84R missense_variant 0.89 0
6:29942933:G W84G missense_variant 0.89 0
6:29942933:A W84R missense_variant 0.89 0
6:29944251:T Q250L missense_variant 0.89 0
6:29944251:C Q250P missense_variant 0.89 0
6:29944251:G Q250R missense_variant 0.89 0
6:29942798:G P39A missense_variant 0.89 0
6:29942798:A P39T missense_variant 0.89 0
6:29942798:T P39S missense_variant 0.89 0
6:29943020:T E113* stop_gained 0.89 0
6:29943543:T D207Y missense_variant 0.89 0
6:29943543:C D207H missense_variant 0.89 0
6:29943543:A D207N missense_variant 0.89 0
6:29944127:T P209S missense_variant 0.89 0
6:29944127:G P209A missense_variant 0.89 0
6:29944127:A P209T missense_variant 0.89 0
6:29944395:T W298L missense_variant 0.88 0
6:29944395:C W298S missense_variant 0.88 0
6:29942882:T Q67* stop_gained 0.88 0
6:29944128:A P209H missense_variant 0.88 0
6:29944128:G P209R missense_variant 0.88 0
6:29944128:T P209L missense_variant 0.88 0
6:29944566:A V321E missense_variant 0.88 0
6:29944566:G V321G missense_variant 0.88 0
6:29944566:C V321A missense_variant 0.88 0
6:29942591:G L13R missense_variant 0.87 0
6:29942591:A L13H missense_variant 0.87 0
6:29942591:C L13P missense_variant 0.87 0
6:29944140:A M213K missense_variant 0.87 0
6:29944140:G M213R missense_variant 0.87 0
6:29944140:C M213T missense_variant 0.87 0
6:29942594:A S14* stop_gained 0.87 0
6:29944376:T K292* stop_gained 0.87 0
6:29945078:G Y344* stop_gained 0.87 0
6:29945078:A Y344* stop_gained 0.87 0
6:29944599:A W332* stop_gained 0.86 0
6:29944614:A S337* stop_gained 0.86 0
6:29944614:G S337* stop_gained 0.86 0
6:29944511:T Q303* stop_gained 0.86 0
6:29942614:T Q21* stop_gained 0.86 0
6:29944238:T E246* stop_gained 0.86 0
6:29943522:T K200* stop_gained 0.86 0
6:29942776:G Y31* stop_gained 0.85 0
6:29942776:A Y31* stop_gained 0.85 0
6:29943504:G R194G missense_variant 0.85 0
6:29943350:G Y142* stop_gained 0.85 0
6:29943350:A Y142* stop_gained 0.85 0
6:29943496:A W191* stop_gained 0.85 0
6:29944331:T E277* stop_gained 0.84 0
6:29945082:T Q346* stop_gained 0.84 0
6:29943378:T E152* stop_gained 0.83 0
6:29943492:T E190* stop_gained 0.83 0
6:29943542:C T206T splice_region_variant 0.83 0
6:29943542:A T206T splice_region_variant 0.83 0
6:29944259:T E253* stop_gained 0.82 0
6:29944367:T G289C missense_variant 0.82 0
6:29944367:A G289S missense_variant 0.82 0
6:29944367:C G289R missense_variant 0.82 0
6:29944351:A C283* stop_gained 0.82 0
6:29944397:T E299* stop_gained 0.82 0
6:29944226:T Q242* stop_gained 0.81 0
6:29944337:T Q279* stop_gained 0.81 0
6:29943417:T Q165* stop_gained 0.81 0
6:29942957:T K92* stop_gained 0.81 0
6:29943310:A S129* stop_gained 0.81 0
6:29942793:T S37F missense_variant 0.81 0
6:29942793:A S37Y missense_variant 0.81 0
6:29942793:G S37C missense_variant 0.81 0
6:29944244:T Q248* stop_gained 0.81 0
6:29944236:T G245V missense_variant 0.81 0
6:29944236:C G245A missense_variant 0.81 0
6:29944236:A G245E missense_variant 0.81 0
6:29943456:T E178* stop_gained 0.80 0
6:29942891:T E70* stop_gained 0.80 0
6:29942871:C D63A missense_variant 0.80 0
6:29942871:T D63V missense_variant 0.80 0
6:29942871:G D63G missense_variant 0.80 0
6:29944394:A W298R missense_variant 0.80 0
6:29944394:G W298G missense_variant 0.80 0
6:29944394:C W298R missense_variant 0.80 0
6:29944345:A Y281* stop_gained 0.78 0
6:29944345:G Y281* stop_gained 0.78 0
6:29944364:T E288* stop_gained 0.78 0
6:29944130:T K210* stop_gained 0.77 0
6:29943432:T K170* stop_gained 0.77 0
6:29944186:A W228* stop_gained 0.77 0
6:29944166:T E222* stop_gained 0.77 0
6:29944359:G Q286R missense_variant 0.77 0
6:29944359:T Q286L missense_variant 0.77 0
6:29944359:C Q286P missense_variant 0.77 0
6:29943300:A D126N missense_variant 0.77 0
6:29943300:C D126H missense_variant 0.77 0
6:29943300:T D126Y missense_variant 0.77 0
6:29943012:C N110T missense_variant 0.77 0
6:29943012:T N110I missense_variant 0.77 0
6:29943012:G N110S missense_variant 0.77 0
6:29944370:A L290M missense_variant 0.76 0
6:29944370:G L290V missense_variant 0.76 0
6:29943513:T E197* stop_gained 0.76 0
6:29942836:A Y51* stop_gained 0.76 0
6:29942836:G Y51* stop_gained 0.76 0
6:29943015:C Q111P missense_variant 0.75 0
6:29943015:T Q111L missense_variant 0.75 0
6:29943015:G Q111R missense_variant 0.75 0
6:29945061:T R339* stop_gained 0.73 0
6:29944600:A W332* stop_gained 0.69 0
6:29945252:T G355V missense_variant 0.69 0
6:29945250:T Q354H missense_variant 0.69 0
6:29945252:A G355D missense_variant 0.69 0
6:29945250:C Q354H missense_variant 0.69 0
6:29945252:C G355A missense_variant 0.69 0
6:29943516:C N198H missense_variant 0.69 0
6:29943516:T N198Y missense_variant 0.69 0
6:29943516:G N198D missense_variant 0.69 0
6:29942835:G Y51C missense_variant 0.69 0
6:29944284:T G261V missense_variant 0.69 0
6:29944284:C G261A missense_variant 0.69 0
6:29942835:C Y51S missense_variant 0.69 0
6:29944284:A G261E missense_variant 0.69 0
6:29942835:T Y51F missense_variant 0.69 0
6:29944246:T Q248H missense_variant 0.68 0
6:29942945:T T88S missense_variant 0.68 0
6:29943290:C M122I missense_variant 0.68 0
6:29943290:T M122I missense_variant 0.68 0
6:29943290:A M122I missense_variant 0.68 0
6:29942945:C T88P missense_variant 0.68 0
6:29942945:G T88A missense_variant 0.68 0
6:29942764:G H27Q missense_variant 0.68 0
6:29942764:A H27Q missense_variant 0.68 0
6:29942766:T S28F missense_variant 0.68 0
6:29942766:G S28C missense_variant 0.68 0
6:29942766:A S28Y missense_variant 0.68 0
6:29942894:A P71T missense_variant 0.67 0
6:29942894:T P71S missense_variant 0.67 0
6:29942894:G P71A missense_variant 0.67 0
6:29944380:G P293R missense_variant 0.66 0
6:29944380:A P293H missense_variant 0.66 0
6:29944380:T P293L missense_variant 0.66 0
6:29942917:C Q78H missense_variant 0.66 0
6:29942917:T Q78H missense_variant 0.66 0
6:29944396:T W298C missense_variant 0.65 0
6:29944396:C W298C missense_variant 0.65 0
6:29942623:A A24T missense_variant 0.65 0
6:29942623:C A24P missense_variant 0.65 0
6:29942623:T A24S missense_variant 0.65 0
6:29944169:C A223P missense_variant 0.64 0
6:29944169:A A223T missense_variant 0.64 0
6:29944169:T A223S missense_variant 0.64 0
6:29943524:C K200N missense_variant 0.62 0
6:29943524:T K200N missense_variant 0.62 0
6:29942777:C F32L missense_variant 0.61 0
6:29942777:A F32I missense_variant 0.61 0
6:29942777:G F32V missense_variant 0.61 0
6:29944298:A Q266K missense_variant 0.61 0
6:29944298:G Q266E missense_variant 0.61 0
6:29945067:T G341* stop_gained 0.60 0
6:29944250:A Q250K missense_variant 0.60 0
6:29944250:G Q250E missense_variant 0.60 0
6:29944199:A Y233N missense_variant 0.60 0
6:29944199:C Y233H missense_variant 0.60 0
6:29944199:G Y233D missense_variant 0.60 0
6:29944332:C E277A missense_variant 0.59 0
6:29944332:G E277G missense_variant 0.59 0
6:29944332:T E277V missense_variant 0.59 0
6:29944326:T S275F missense_variant 0.58 0
6:29944326:A S275Y missense_variant 0.58 0
6:29944326:G S275C missense_variant 0.58 0
6:29944305:C W268S missense_variant 0.58 0
6:29944305:T W268L missense_variant 0.58 0
6:29944160:A D220N missense_variant 0.58 0
6:29944160:T D220Y missense_variant 0.58 0
6:29944160:C D220H missense_variant 0.58 0
6:29942908:C W75C missense_variant 0.58 0
6:29942908:T W75C missense_variant 0.58 0
6:29944172:G T224A missense_variant 0.58 0
6:29944172:T T224S missense_variant 0.58 0
6:29944172:C T224P missense_variant 0.58 0
6:29944254:G D251G missense_variant 0.57 0
6:29944254:T D251V missense_variant 0.57 0
6:29944254:C D251A missense_variant 0.57 0
6:29943508:T Y195F missense_variant 0.57 0
6:29943508:C Y195S missense_variant 0.57 0
6:29943508:G Y195C missense_variant 0.57 0
6:29943349:C Y142S missense_variant 0.57 0
6:29943349:T Y142F missense_variant 0.57 0
6:29943349:G Y142C missense_variant 0.57 0
6:29944391:T R297* stop_gained 0.55 0
6:29943395:T W157C missense_variant 0.54 0
6:29943395:C W157C missense_variant 0.54 0
6:29945248:T Q354* stop_gained 0.54 0
6:29942934:T W84L missense_variant 0.53 0
6:29942934:C W84S missense_variant 0.53 0
6:29944260:C E253A missense_variant 0.53 0
6:29944260:T E253V missense_variant 0.53 0
6:29944260:G E253G missense_variant 0.53 0
6:29943333:C Y137H missense_variant 0.53 0
6:29943333:G Y137D missense_variant 0.53 0
6:29943333:A Y137N missense_variant 0.53 0
6:29942622:A W23* stop_gained 0.53 0
6:29945277:A C363* stop_gained 0.52 0
6:29943427:T K168M missense_variant 0.52 0
6:29943427:C K168T missense_variant 0.52 0
6:29943427:G K168R missense_variant 0.52 0
In silico saturation mutagenesis
Alt text Show figure caption
Cancer type Selected cancer type Mutational discovery Index Feature Complexity
(DLBCL) Diffuse large B-cell lymphoma DLBCL 0.42 0.11