MAP3K1
BRCA
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Select a mutation to see further information
| Mutation | AA change | Consequence type | BoostDM score | IntOGen frequency |
|---|---|---|---|---|
| 5:56864852:A | L318* | stop_gained | 1.00 | 2 |
| 5:56872913:T | R532* | stop_gained | 1.00 | 2 |
| 5:56881841:T | Q881* | stop_gained | 0.99 | 2 |
| 5:56865403:T | Q367* | stop_gained | 1.00 | 1 |
| 5:56888238:T | Q1424* | stop_gained | 1.00 | 1 |
| 5:56883635:T | Q1259* | stop_gained | 1.00 | 1 |
| 5:56875250:A | C635* | stop_gained | 1.00 | 1 |
| 5:56875264:A | S640* | stop_gained | 1.00 | 1 |
| 5:56887407:T | Q1382* | stop_gained | 1.00 | 1 |
| 5:56864789:A | S297* | stop_gained | 1.00 | 1 |
| 5:56864932:T | Q345* | stop_gained | 1.00 | 1 |
| 5:56872922:T | Q535* | stop_gained | 1.00 | 1 |
| 5:56882342:T | Q1048* | stop_gained | 1.00 | 1 |
| 5:56882270:T | K1024* | stop_gained | 1.00 | 1 |
| 5:56882750:T | E1184* | stop_gained | 1.00 | 1 |
| 5:56864887:T | G330* | stop_gained | 1.00 | 1 |
| 5:56884787:T | E1315* | stop_gained | 1.00 | 1 |
| 5:56871926:T | E440* | stop_gained | 1.00 | 1 |
| 5:56875146:T | E601* | stop_gained | 1.00 | 1 |
| 5:56879082:T | K690* | stop_gained | 1.00 | 1 |
| 5:56872892:T | Q525* | stop_gained | 1.00 | 1 |
| 5:56859872:G | S264* | stop_gained | 1.00 | 1 |
| 5:56880721:T | Q700* | stop_gained | 1.00 | 1 |
| 5:56881190:T | R763* | stop_gained | 1.00 | 1 |
| 5:56882258:T | Q1020* | stop_gained | 1.00 | 1 |
| 5:56865968:A | S431* | stop_gained | 1.00 | 1 |
| 5:56875242:T | E633* | stop_gained | 1.00 | 1 |
| 5:56882151:G | S984* | stop_gained | 1.00 | 1 |
| 5:56885980:G | S1344* | stop_gained | 0.99 | 1 |
| 5:56882316:G | S1039* | stop_gained | 0.99 | 1 |
| 5:56882316:A | S1039* | stop_gained | 0.99 | 1 |
| 5:56881673:T | R825* | stop_gained | 0.99 | 1 |
| 5:56864850:A | Y317* | stop_gained | 0.99 | 1 |
| 5:56882430:G | S1077* | stop_gained | 0.99 | 1 |
| 5:56864934:A | Q345Q | splice_region_variant | 0.82 | 1 |
| 5:56856722:A | L202* | stop_gained | 1.00 | 0 |
| 5:56856635:A | L173* | stop_gained | 1.00 | 0 |
| 5:56865432:A | W376* | stop_gained | 1.00 | 0 |
| 5:56865454:T | E384* | stop_gained | 1.00 | 0 |
| 5:56888241:T | Q1425* | stop_gained | 1.00 | 0 |
| 5:56865409:T | E369* | stop_gained | 1.00 | 0 |
| 5:56865358:T | G352* | stop_gained | 1.00 | 0 |
| 5:56883677:T | Q1273* | stop_gained | 1.00 | 0 |
| 5:56883641:T | Q1261* | stop_gained | 1.00 | 0 |
| 5:56883599:T | Q1247* | stop_gained | 1.00 | 0 |
| 5:56883602:T | Q1248* | stop_gained | 1.00 | 0 |
| 5:56884709:T | E1289* | stop_gained | 1.00 | 0 |
| 5:56875289:G | Y648* | stop_gained | 1.00 | 0 |
| 5:56875264:G | S640* | stop_gained | 1.00 | 0 |
| 5:56875289:A | Y648* | stop_gained | 1.00 | 0 |
| 5:56887489:G | L1409* | stop_gained | 1.00 | 0 |
| 5:56887447:A | L1395* | stop_gained | 1.00 | 0 |
| 5:56887489:A | L1409* | stop_gained | 1.00 | 0 |
| 5:56887387:A | L1375* | stop_gained | 1.00 | 0 |
| 5:56872702:A | W495* | stop_gained | 1.00 | 0 |
| 5:56882766:A | L1189* | stop_gained | 1.00 | 0 |
| 5:56882766:G | L1189* | stop_gained | 1.00 | 0 |
| 5:56886007:A | L1353* | stop_gained | 1.00 | 0 |
| 5:56887485:T | Q1408* | stop_gained | 1.00 | 0 |
| 5:56887479:T | Q1406* | stop_gained | 1.00 | 0 |
| 5:56887453:G | S1397* | stop_gained | 1.00 | 0 |
| 5:56887453:A | S1397* | stop_gained | 1.00 | 0 |
| 5:56885950:A | L1334* | stop_gained | 1.00 | 0 |
| 5:56886007:G | L1353* | stop_gained | 1.00 | 0 |
| 5:56881955:T | K919* | stop_gained | 1.00 | 0 |
| 5:56864857:T | Q320* | stop_gained | 1.00 | 0 |
| 5:56893637:G | S1499* | stop_gained | 1.00 | 0 |
| 5:56893637:A | S1499* | stop_gained | 1.00 | 0 |
| 5:56872026:G | S473* | stop_gained | 1.00 | 0 |
| 5:56872026:A | S473* | stop_gained | 1.00 | 0 |
| 5:56864737:T | Q280* | stop_gained | 1.00 | 0 |
| 5:56872021:A | C471* | stop_gained | 1.00 | 0 |
| 5:56864774:A | S292* | stop_gained | 1.00 | 0 |
| 5:56864774:G | S292* | stop_gained | 1.00 | 0 |
| 5:56864789:G | S297* | stop_gained | 1.00 | 0 |
| 5:56871929:T | Q441* | stop_gained | 1.00 | 0 |
| 5:56864860:T | Q321* | stop_gained | 1.00 | 0 |
| 5:56865869:G | S398* | stop_gained | 1.00 | 0 |
| 5:56865869:A | S398* | stop_gained | 1.00 | 0 |
| 5:56865923:G | S416* | stop_gained | 1.00 | 0 |
| 5:56865923:A | S416* | stop_gained | 1.00 | 0 |
| 5:56865914:G | S413* | stop_gained | 1.00 | 0 |
| 5:56865914:A | S413* | stop_gained | 1.00 | 0 |
| 5:56887455:T | K1398* | stop_gained | 1.00 | 0 |
| 5:56856640:T | K175* | stop_gained | 1.00 | 0 |
| 5:56859784:T | E235* | stop_gained | 1.00 | 0 |
| 5:56859772:T | E231* | stop_gained | 1.00 | 0 |
| 5:56881662:A | L821* | stop_gained | 1.00 | 0 |
| 5:56881605:A | L802* | stop_gained | 1.00 | 0 |
| 5:56881593:G | L798* | stop_gained | 1.00 | 0 |
| 5:56881593:A | L798* | stop_gained | 1.00 | 0 |
| 5:56878987:A | L658* | stop_gained | 1.00 | 0 |
| 5:56881767:A | L856* | stop_gained | 1.00 | 0 |
| 5:56881713:G | L838* | stop_gained | 1.00 | 0 |
| 5:56881713:A | L838* | stop_gained | 1.00 | 0 |
| 5:56882723:T | Q1175* | stop_gained | 1.00 | 0 |
| 5:56882652:A | S1151* | stop_gained | 1.00 | 0 |
| 5:56882346:G | S1049* | stop_gained | 1.00 | 0 |
| 5:56882346:A | S1049* | stop_gained | 1.00 | 0 |
| 5:56882093:T | Q965* | stop_gained | 1.00 | 0 |
| 5:56882069:T | Q957* | stop_gained | 1.00 | 0 |
| 5:56886022:A | S1358* | stop_gained | 1.00 | 0 |
| 5:56882652:G | S1151* | stop_gained | 1.00 | 0 |
| 5:56886003:T | Q1352* | stop_gained | 1.00 | 0 |
| 5:56886039:T | Q1364* | stop_gained | 1.00 | 0 |
| 5:56882057:T | K953* | stop_gained | 1.00 | 0 |
| 5:56882732:T | K1178* | stop_gained | 1.00 | 0 |
| 5:56886060:T | K1371* | stop_gained | 1.00 | 0 |
| 5:56885973:T | K1342* | stop_gained | 1.00 | 0 |
| 5:56882381:T | K1061* | stop_gained | 1.00 | 0 |
| 5:56882738:T | K1180* | stop_gained | 1.00 | 0 |
| 5:56885958:T | K1337* | stop_gained | 1.00 | 0 |
| 5:56872979:T | K554* | stop_gained | 1.00 | 0 |
| 5:56859883:T | G268* | stop_gained | 1.00 | 0 |
| 5:56859874:T | E265* | stop_gained | 1.00 | 0 |
| 5:56856679:T | K188* | stop_gained | 1.00 | 0 |
| 5:56856685:T | K190* | stop_gained | 1.00 | 0 |
| 5:56881925:T | E909* | stop_gained | 1.00 | 0 |
| 5:56880745:T | E708* | stop_gained | 1.00 | 0 |
| 5:56880769:T | E716* | stop_gained | 1.00 | 0 |
| 5:56880766:T | G715* | stop_gained | 1.00 | 0 |
| 5:56881142:T | E747* | stop_gained | 1.00 | 0 |
| 5:56881130:T | G743* | stop_gained | 1.00 | 0 |
| 5:56880802:T | G727* | stop_gained | 1.00 | 0 |
| 5:56880787:T | E722* | stop_gained | 1.00 | 0 |
| 5:56881214:T | E771* | stop_gained | 1.00 | 0 |
| 5:56881156:A | W751* | stop_gained | 1.00 | 0 |
| 5:56881155:A | W751* | stop_gained | 1.00 | 0 |
| 5:56881799:T | E867* | stop_gained | 1.00 | 0 |
| 5:56879028:T | E672* | stop_gained | 1.00 | 0 |
| 5:56881784:T | E862* | stop_gained | 1.00 | 0 |
| 5:56881790:T | E864* | stop_gained | 1.00 | 0 |
| 5:56865970:T | E432* | stop_gained | 1.00 | 0 |
| 5:56880773:A | L717* | stop_gained | 1.00 | 0 |
| 5:56881116:A | L738* | stop_gained | 1.00 | 0 |
| 5:56881116:G | L738* | stop_gained | 1.00 | 0 |
| 5:56880743:A | L707* | stop_gained | 1.00 | 0 |
| 5:56888355:T | K1463* | stop_gained | 1.00 | 0 |
| 5:56884790:T | K1316* | stop_gained | 1.00 | 0 |
| 5:56888304:T | K1446* | stop_gained | 1.00 | 0 |
| 5:56888325:T | K1453* | stop_gained | 1.00 | 0 |
| 5:56881202:T | E767* | stop_gained | 1.00 | 0 |
| 5:56865904:T | K410* | stop_gained | 1.00 | 0 |
| 5:56865847:T | K391* | stop_gained | 1.00 | 0 |
| 5:56882237:T | R1013* | stop_gained | 1.00 | 0 |
| 5:56856616:T | K167* | stop_gained | 1.00 | 0 |
| 5:56871914:T | K436* | stop_gained | 1.00 | 0 |
| 5:56865445:T | K381* | stop_gained | 1.00 | 0 |
| 5:56872004:T | K466* | stop_gained | 1.00 | 0 |
| 5:56856610:T | E165* | stop_gained | 1.00 | 0 |
| 5:56856604:T | E163* | stop_gained | 1.00 | 0 |
| 5:56864908:T | K337* | stop_gained | 1.00 | 0 |
| 5:56864827:T | K310* | stop_gained | 1.00 | 0 |
| 5:56893651:T | K1504* | stop_gained | 1.00 | 0 |
| 5:56882837:T | G1213* | stop_gained | 1.00 | 0 |
| 5:56882756:T | E1186* | stop_gained | 1.00 | 0 |
| 5:56882654:T | E1152* | stop_gained | 1.00 | 0 |
| 5:56882609:T | E1137* | stop_gained | 1.00 | 0 |
| 5:56885934:T | G1329* | stop_gained | 1.00 | 0 |
| 5:56885964:T | G1339* | stop_gained | 1.00 | 0 |
| 5:56886000:T | E1351* | stop_gained | 1.00 | 0 |
| 5:56872925:T | E536* | stop_gained | 1.00 | 0 |
| 5:56882048:T | E950* | stop_gained | 1.00 | 0 |
| 5:56875230:T | G629* | stop_gained | 1.00 | 0 |
| 5:56882528:T | E1110* | stop_gained | 1.00 | 0 |
| 5:56882552:T | E1118* | stop_gained | 1.00 | 0 |
| 5:56872991:T | E558* | stop_gained | 1.00 | 0 |
| 5:56872998:A | W560* | stop_gained | 1.00 | 0 |
| 5:56872999:A | W560* | stop_gained | 1.00 | 0 |
| 5:56872829:T | E504* | stop_gained | 1.00 | 0 |
| 5:56882759:T | E1187* | stop_gained | 1.00 | 0 |
| 5:56882579:T | E1127* | stop_gained | 1.00 | 0 |
| 5:56882753:T | E1185* | stop_gained | 1.00 | 0 |
| 5:56882744:T | E1182* | stop_gained | 1.00 | 0 |
| 5:56885976:T | E1343* | stop_gained | 1.00 | 0 |
| 5:56882735:T | E1179* | stop_gained | 1.00 | 0 |
| 5:56886033:T | E1362* | stop_gained | 1.00 | 0 |
| 5:56882675:T | E1159* | stop_gained | 1.00 | 0 |
| 5:56872646:T | E477* | stop_gained | 1.00 | 0 |
| 5:56872641:A | W475* | stop_gained | 1.00 | 0 |
| 5:56872642:A | W475* | stop_gained | 1.00 | 0 |
| 5:56872667:T | E484* | stop_gained | 1.00 | 0 |
| 5:56887482:T | G1407* | stop_gained | 1.00 | 0 |
| 5:56887473:T | E1404* | stop_gained | 1.00 | 0 |
| 5:56887518:T | E1419* | stop_gained | 1.00 | 0 |
| 5:56887458:T | G1399* | stop_gained | 1.00 | 0 |
| 5:56887470:T | G1403* | stop_gained | 1.00 | 0 |
| 5:56887431:T | G1390* | stop_gained | 1.00 | 0 |
| 5:56871965:T | E453* | stop_gained | 1.00 | 0 |
| 5:56884691:T | E1283* | stop_gained | 1.00 | 0 |
| 5:56883614:T | G1252* | stop_gained | 1.00 | 0 |
| 5:56865832:T | E386* | stop_gained | 1.00 | 0 |
| 5:56884697:T | E1285* | stop_gained | 1.00 | 0 |
| 5:56884700:T | E1286* | stop_gained | 1.00 | 0 |
| 5:56883589:A | W1243* | stop_gained | 1.00 | 0 |
| 5:56864890:T | G331* | stop_gained | 1.00 | 0 |
| 5:56883588:A | W1243* | stop_gained | 1.00 | 0 |
| 5:56883584:T | E1242* | stop_gained | 1.00 | 0 |
| 5:56884721:T | E1293* | stop_gained | 1.00 | 0 |
| 5:56884724:T | E1294* | stop_gained | 1.00 | 0 |
| 5:56884775:T | G1311* | stop_gained | 1.00 | 0 |
| 5:56883575:T | E1239* | stop_gained | 1.00 | 0 |
| 5:56883545:T | G1229* | stop_gained | 1.00 | 0 |
| 5:56883533:T | E1225* | stop_gained | 1.00 | 0 |
| 5:56864806:T | E303* | stop_gained | 1.00 | 0 |
| 5:56871920:T | E438* | stop_gained | 1.00 | 0 |
| 5:56871923:T | E439* | stop_gained | 1.00 | 0 |
| 5:56864803:T | E302* | stop_gained | 1.00 | 0 |
| 5:56884814:T | E1324* | stop_gained | 1.00 | 0 |
| 5:56884818:A | W1325* | stop_gained | 1.00 | 0 |
| 5:56883650:T | G1264* | stop_gained | 1.00 | 0 |
| 5:56871968:T | E454* | stop_gained | 1.00 | 0 |
| 5:56871986:T | E460* | stop_gained | 1.00 | 0 |
| 5:56884819:A | W1325* | stop_gained | 1.00 | 0 |
| 5:56872649:T | E478* | stop_gained | 1.00 | 0 |
| 5:56856724:T | E203* | stop_gained | 1.00 | 0 |
| 5:56856720:A | W201* | stop_gained | 1.00 | 0 |
| 5:56856719:A | W201* | stop_gained | 1.00 | 0 |
| 5:56856715:T | E200* | stop_gained | 1.00 | 0 |
| 5:56856708:A | W197* | stop_gained | 1.00 | 0 |
| 5:56856707:A | W197* | stop_gained | 1.00 | 0 |
| 5:56856676:T | E187* | stop_gained | 1.00 | 0 |
| 5:56856661:T | E182* | stop_gained | 1.00 | 0 |
| 5:56856658:T | E181* | stop_gained | 1.00 | 0 |
| 5:56888247:T | G1427* | stop_gained | 1.00 | 0 |
| 5:56888266:A | W1433* | stop_gained | 1.00 | 0 |
| 5:56888267:A | W1433* | stop_gained | 1.00 | 0 |
| 5:56875038:T | G565* | stop_gained | 1.00 | 0 |
| 5:56875044:T | E567* | stop_gained | 1.00 | 0 |
| 5:56893677:A | W1512* | stop_gained | 1.00 | 0 |
| 5:56888289:T | E1441* | stop_gained | 1.00 | 0 |
| 5:56875075:A | W577* | stop_gained | 1.00 | 0 |
| 5:56875076:A | W577* | stop_gained | 1.00 | 0 |
| 5:56888314:A | W1449* | stop_gained | 1.00 | 0 |
| 5:56875086:T | E581* | stop_gained | 1.00 | 0 |
| 5:56893676:A | W1512* | stop_gained | 1.00 | 0 |
| 5:56888315:A | W1449* | stop_gained | 1.00 | 0 |
| 5:56888322:T | E1452* | stop_gained | 1.00 | 0 |
| 5:56893642:T | E1501* | stop_gained | 1.00 | 0 |
| 5:56893609:T | E1490* | stop_gained | 1.00 | 0 |
| 5:56865431:A | W376* | stop_gained | 1.00 | 0 |
| 5:56883656:T | G1266* | stop_gained | 1.00 | 0 |
| 5:56883674:T | K1272* | stop_gained | 1.00 | 0 |
| 5:56883593:T | K1245* | stop_gained | 1.00 | 0 |
| 5:56875290:T | K649* | stop_gained | 1.00 | 0 |
| 5:56872697:T | K494* | stop_gained | 1.00 | 0 |
| 5:56881256:T | E785* | stop_gained | 1.00 | 0 |
| 5:56878980:T | K656* | stop_gained | 1.00 | 0 |
| 5:56881706:T | K836* | stop_gained | 1.00 | 0 |
| 5:56881640:T | K814* | stop_gained | 1.00 | 0 |
| 5:56881577:T | K793* | stop_gained | 1.00 | 0 |
| 5:56859751:T | E224* | stop_gained | 1.00 | 0 |
| 5:56880796:T | K725* | stop_gained | 1.00 | 0 |
| 5:56880754:T | K711* | stop_gained | 1.00 | 0 |
| 5:56875194:T | G617* | stop_gained | 1.00 | 0 |
| 5:56859868:T | K263* | stop_gained | 1.00 | 0 |
| 5:56859721:T | K214* | stop_gained | 1.00 | 0 |
| 5:56893565:G | S1475* | stop_gained | 1.00 | 0 |
| 5:56884694:T | Q1284* | stop_gained | 1.00 | 0 |
| 5:56893556:A | S1472* | stop_gained | 1.00 | 0 |
| 5:56893565:A | S1475* | stop_gained | 1.00 | 0 |
| 5:56881265:T | E788* | stop_gained | 1.00 | 0 |
| 5:56883663:A | L1268* | stop_gained | 1.00 | 0 |
| 5:56883663:G | L1268* | stop_gained | 1.00 | 0 |
| 5:56882787:G | S1196* | stop_gained | 1.00 | 0 |
| 5:56882787:A | S1196* | stop_gained | 1.00 | 0 |
| 5:56882795:T | Q1199* | stop_gained | 1.00 | 0 |
| 5:56882819:T | Q1207* | stop_gained | 1.00 | 0 |
| 5:56881197:A | L765* | stop_gained | 1.00 | 0 |
| 5:56881200:A | L766* | stop_gained | 1.00 | 0 |
| 5:56888347:A | L1460* | stop_gained | 1.00 | 0 |
| 5:56893571:A | L1477* | stop_gained | 1.00 | 0 |
| 5:56893583:A | L1481* | stop_gained | 1.00 | 0 |
| 5:56893583:G | L1481* | stop_gained | 1.00 | 0 |
| 5:56893607:A | L1489* | stop_gained | 1.00 | 0 |
| 5:56893607:G | L1489* | stop_gained | 1.00 | 0 |
| 5:56881985:T | E929* | stop_gained | 1.00 | 0 |
| 5:56875060:G | L572* | stop_gained | 1.00 | 0 |
| 5:56875060:A | L572* | stop_gained | 1.00 | 0 |
| 5:56875135:A | L597* | stop_gained | 1.00 | 0 |
| 5:56875309:A | L655* | stop_gained | 1.00 | 0 |
| 5:56875309:G | L655* | stop_gained | 1.00 | 0 |
| 5:56884773:A | L1310* | stop_gained | 1.00 | 0 |
| 5:56865944:G | S423* | stop_gained | 1.00 | 0 |
| 5:56865944:A | S423* | stop_gained | 1.00 | 0 |
| 5:56856619:T | E168* | stop_gained | 1.00 | 0 |
| 5:56881973:T | E925* | stop_gained | 1.00 | 0 |
| 5:56872952:T | G545* | stop_gained | 1.00 | 0 |
| 5:56882858:T | Q1220* | stop_gained | 1.00 | 0 |
| 5:56882597:T | E1133* | stop_gained | 1.00 | 0 |
| 5:56881629:A | S810* | stop_gained | 1.00 | 0 |
| 5:56879043:T | Q677* | stop_gained | 1.00 | 0 |
| 5:56881629:G | S810* | stop_gained | 1.00 | 0 |
| 5:56882684:T | E1162* | stop_gained | 1.00 | 0 |
| 5:56864852:G | L318* | stop_gained | 1.00 | 0 |
| 5:56871948:A | L447* | stop_gained | 1.00 | 0 |
| 5:56871951:A | L448* | stop_gained | 1.00 | 0 |
| 5:56865428:A | L375* | stop_gained | 1.00 | 0 |
| 5:56865428:G | L375* | stop_gained | 1.00 | 0 |
| 5:56865839:A | L388* | stop_gained | 1.00 | 0 |
| 5:56880760:T | Q713* | stop_gained | 1.00 | 0 |
| 5:56880734:A | S704* | stop_gained | 1.00 | 0 |
| 5:56880734:G | S704* | stop_gained | 1.00 | 0 |
| 5:56881157:T | Q752* | stop_gained | 1.00 | 0 |
| 5:56872874:T | Q519* | stop_gained | 1.00 | 0 |
| 5:56881715:T | E839* | stop_gained | 1.00 | 0 |
| 5:56882840:T | E1214* | stop_gained | 1.00 | 0 |
| 5:56881820:T | E874* | stop_gained | 1.00 | 0 |
| 5:56882831:T | E1211* | stop_gained | 1.00 | 0 |
| 5:56882549:T | E1117* | stop_gained | 1.00 | 0 |
| 5:56865877:T | K401* | stop_gained | 1.00 | 0 |
| 5:56865436:T | K378* | stop_gained | 1.00 | 0 |
| 5:56882264:T | Q1022* | stop_gained | 1.00 | 0 |
| 5:56872836:A | S506* | stop_gained | 1.00 | 0 |
| 5:56872836:G | S506* | stop_gained | 1.00 | 0 |
| 5:56882219:T | Q1007* | stop_gained | 1.00 | 0 |
| 5:56859854:A | S258* | stop_gained | 1.00 | 0 |
| 5:56859872:A | S264* | stop_gained | 1.00 | 0 |
| 5:56859854:G | S258* | stop_gained | 1.00 | 0 |
| 5:56881160:T | E753* | stop_gained | 1.00 | 0 |
| 5:56882303:T | E1035* | stop_gained | 1.00 | 0 |
| 5:56882222:T | G1008* | stop_gained | 1.00 | 0 |
| 5:56856709:T | K198* | stop_gained | 1.00 | 0 |
| 5:56883560:T | K1234* | stop_gained | 1.00 | 0 |
| 5:56883554:T | K1232* | stop_gained | 1.00 | 0 |
| 5:56875215:T | Q624* | stop_gained | 1.00 | 0 |
| 5:56881250:T | Q783* | stop_gained | 1.00 | 0 |
| 5:56882432:T | K1078* | stop_gained | 1.00 | 0 |
| 5:56873003:T | Q562* | stop_gained | 1.00 | 0 |
| 5:56882726:T | K1176* | stop_gained | 1.00 | 0 |
| 5:56885938:A | S1330* | stop_gained | 1.00 | 0 |
| 5:56882081:T | R961* | stop_gained | 1.00 | 0 |
| 5:56882414:T | K1072* | stop_gained | 1.00 | 0 |
| 5:56882825:T | Q1209* | stop_gained | 1.00 | 0 |
| 5:56872958:T | Q547* | stop_gained | 1.00 | 0 |
| 5:56887410:T | R1383* | stop_gained | 1.00 | 0 |
| 5:56872880:T | Q521* | stop_gained | 1.00 | 0 |
| 5:56872889:T | Q524* | stop_gained | 1.00 | 0 |
| 5:56872961:T | Q548* | stop_gained | 1.00 | 0 |
| 5:56882417:T | Q1073* | stop_gained | 1.00 | 0 |
| 5:56882555:T | K1119* | stop_gained | 1.00 | 0 |
| 5:56882009:T | G937* | stop_gained | 1.00 | 0 |
| 5:56865941:A | S422* | stop_gained | 1.00 | 0 |
| 5:56865941:G | S422* | stop_gained | 1.00 | 0 |
| 5:56881928:T | K910* | stop_gained | 1.00 | 0 |
| 5:56859745:T | G222* | stop_gained | 1.00 | 0 |
| 5:56872833:A | L505* | stop_gained | 1.00 | 0 |
| 5:56865968:G | S431* | stop_gained | 1.00 | 0 |
| 5:56882129:T | Q977* | stop_gained | 1.00 | 0 |
| 5:56882321:T | K1041* | stop_gained | 1.00 | 0 |
| 5:56872895:T | Q526* | stop_gained | 1.00 | 0 |
| 5:56882075:T | K959* | stop_gained | 1.00 | 0 |
| 5:56882565:G | L1122* | stop_gained | 1.00 | 0 |
| 5:56882565:A | L1122* | stop_gained | 1.00 | 0 |
| 5:56882100:A | L967* | stop_gained | 1.00 | 0 |
| 5:56872986:A | L556* | stop_gained | 1.00 | 0 |
| 5:56872986:G | L556* | stop_gained | 1.00 | 0 |
| 5:56865901:T | Q409* | stop_gained | 1.00 | 0 |
| 5:56815778:T | E69* | stop_gained | 1.00 | 0 |
| 5:56815796:T | E75* | stop_gained | 1.00 | 0 |
| 5:56859892:T | R271* | stop_gained | 1.00 | 0 |
| 5:56875228:A | S628* | stop_gained | 1.00 | 0 |
| 5:56875228:G | S628* | stop_gained | 1.00 | 0 |
| 5:56875253:A | C636* | stop_gained | 1.00 | 0 |
| 5:56893615:T | Q1492* | stop_gained | 1.00 | 0 |
| 5:56872674:G | L486* | stop_gained | 1.00 | 0 |
| 5:56865844:T | Q390* | stop_gained | 1.00 | 0 |
| 5:56872674:A | L486* | stop_gained | 1.00 | 0 |
| 5:56882678:T | K1160* | stop_gained | 1.00 | 0 |
| 5:56882309:T | K1037* | stop_gained | 1.00 | 0 |
| 5:56881937:T | K913* | stop_gained | 1.00 | 0 |
| 5:56882207:T | K1003* | stop_gained | 1.00 | 0 |
| 5:56882291:T | R1031* | stop_gained | 1.00 | 0 |
| 5:56875155:T | G604* | stop_gained | 1.00 | 0 |
| 5:56886051:T | R1368* | stop_gained | 1.00 | 0 |
| 5:56859817:T | K246* | stop_gained | 1.00 | 0 |
| 5:56881574:T | K792* | stop_gained | 1.00 | 0 |
| 5:56859895:T | K272* | stop_gained | 1.00 | 0 |
| 5:56859736:T | K219* | stop_gained | 1.00 | 0 |
| 5:56882648:T | K1150* | stop_gained | 1.00 | 0 |
| 5:56872701:A | W495* | stop_gained | 1.00 | 0 |
| 5:56882282:T | Q1028* | stop_gained | 1.00 | 0 |
| 5:56865443:G | L380* | stop_gained | 1.00 | 0 |
| 5:56865443:A | L380* | stop_gained | 1.00 | 0 |
| 5:56872907:T | G530* | stop_gained | 1.00 | 0 |
| 5:56879037:T | K675* | stop_gained | 1.00 | 0 |
| 5:56865416:G | S371* | stop_gained | 1.00 | 0 |
| 5:56865416:A | S371* | stop_gained | 1.00 | 0 |
| 5:56882151:A | S984* | stop_gained | 1.00 | 0 |
| 5:56882702:T | K1168* | stop_gained | 1.00 | 0 |
| 5:56882098:A | C966* | stop_gained | 1.00 | 0 |
| 5:56865433:T | R377* | stop_gained | 1.00 | 0 |
| 5:56883563:T | Q1235* | stop_gained | 1.00 | 0 |
| 5:56881892:T | E898* | stop_gained | 1.00 | 0 |
| 5:56881704:G | S835* | stop_gained | 1.00 | 0 |
| 5:56882731:A | C1177* | stop_gained | 1.00 | 0 |
| 5:56882625:G | S1142* | stop_gained | 1.00 | 0 |
| 5:56882625:A | S1142* | stop_gained | 1.00 | 0 |
| 5:56881704:A | S835* | stop_gained | 1.00 | 0 |
| 5:56856664:T | R183* | stop_gained | 1.00 | 0 |
| 5:56872658:T | R481* | stop_gained | 1.00 | 0 |
| 5:56879023:G | L670* | stop_gained | 1.00 | 0 |
| 5:56879023:A | L670* | stop_gained | 1.00 | 0 |
| 5:56864764:T | R289* | stop_gained | 1.00 | 0 |
| 5:56881146:A | S748* | stop_gained | 1.00 | 0 |
| 5:56881146:G | S748* | stop_gained | 1.00 | 0 |
| 5:56881812:A | L871* | stop_gained | 1.00 | 0 |
| 5:56859739:T | G220* | stop_gained | 1.00 | 0 |
| 5:56882420:T | G1074* | stop_gained | 0.99 | 0 |
| 5:56882051:T | Q951* | stop_gained | 0.99 | 0 |
| 5:56885980:A | S1344* | stop_gained | 0.99 | 0 |
| 5:56882115:A | L972* | stop_gained | 0.99 | 0 |
| 5:56882115:G | L972* | stop_gained | 0.99 | 0 |
| 5:56880784:T | R721* | stop_gained | 0.99 | 0 |
| 5:56859898:T | R273* | stop_gained | 0.99 | 0 |
| 5:56815763:T | K64* | stop_gained | 0.99 | 0 |
| 5:56815754:T | Q61* | stop_gained | 0.99 | 0 |
| 5:56881607:T | Q803* | stop_gained | 0.99 | 0 |
| 5:56882861:T | Q1221* | stop_gained | 0.99 | 0 |
| 5:56879031:T | R673* | stop_gained | 0.99 | 0 |
| 5:56882390:T | R1064* | stop_gained | 0.99 | 0 |
| 5:56872911:A | S531* | stop_gained | 0.99 | 0 |
| 5:56872911:G | S531* | stop_gained | 0.99 | 0 |
| 5:56815916:T | G115* | stop_gained | 0.99 | 0 |
| 5:56815853:T | E94* | stop_gained | 0.99 | 0 |
| 5:56872877:T | Q520* | stop_gained | 0.99 | 0 |
| 5:56859790:T | Q237* | stop_gained | 0.99 | 0 |
| 5:56882213:T | R1005* | stop_gained | 0.99 | 0 |
| 5:56879046:T | R678* | stop_gained | 0.99 | 0 |
| 5:56871985:A | C459* | stop_gained | 0.99 | 0 |
| 5:56815610:T | G13* | stop_gained | 0.99 | 0 |
| 5:56859806:A | S242* | stop_gained | 0.99 | 0 |
| 5:56859806:G | S242* | stop_gained | 0.99 | 0 |
| 5:56875068:T | R575* | stop_gained | 0.99 | 0 |
| 5:56865938:A | L421* | stop_gained | 0.99 | 0 |
| 5:56882022:G | S941* | stop_gained | 0.99 | 0 |
| 5:56882022:A | S941* | stop_gained | 0.99 | 0 |
| 5:56881971:G | S924* | stop_gained | 0.99 | 0 |
| 5:56881971:A | S924* | stop_gained | 0.99 | 0 |
| 5:56859823:T | R248* | stop_gained | 0.99 | 0 |
| 5:56815709:T | E46* | stop_gained | 0.99 | 0 |
| 5:56881808:T | Q870* | stop_gained | 0.99 | 0 |
| 5:56872691:T | R492* | stop_gained | 0.99 | 0 |
| 5:56879055:T | Q681* | stop_gained | 0.99 | 0 |
| 5:56893627:T | R1496* | stop_gained | 0.99 | 0 |
| 5:56883572:T | R1238* | stop_gained | 0.99 | 0 |
| 5:56872664:T | R483* | stop_gained | 0.99 | 0 |
| 5:56881883:T | E895* | stop_gained | 0.99 | 0 |
| 5:56884676:T | R1278* | stop_gained | 0.99 | 0 |
| 5:56815640:T | E23* | stop_gained | 0.99 | 0 |
| 5:56882701:A | Y1167* | stop_gained | 0.99 | 0 |
| 5:56872655:T | R480* | stop_gained | 0.99 | 0 |
| 5:56882701:G | Y1167* | stop_gained | 0.99 | 0 |
| 5:56881934:T | G912* | stop_gained | 0.99 | 0 |
| 5:56856739:T | R208* | stop_gained | 0.99 | 0 |
| 5:56816027:T | E152* | stop_gained | 0.99 | 0 |
| 5:56864850:G | Y317* | stop_gained | 0.99 | 0 |
| 5:56875058:A | C571* | stop_gained | 0.99 | 0 |
| 5:56887416:T | R1385* | stop_gained | 0.99 | 0 |
| 5:56871997:A | C463* | stop_gained | 0.99 | 0 |
| 5:56893585:T | R1482* | stop_gained | 0.99 | 0 |
| 5:56882355:A | L1052* | stop_gained | 0.99 | 0 |
| 5:56875176:T | G611* | stop_gained | 0.99 | 0 |
| 5:56881649:T | R817* | stop_gained | 0.99 | 0 |
| 5:56893621:T | Q1494* | stop_gained | 0.99 | 0 |
| 5:56872902:A | L528* | stop_gained | 0.99 | 0 |
| 5:56888300:A | C1444* | stop_gained | 0.99 | 0 |
| 5:56815605:A | S11* | stop_gained | 0.99 | 0 |
| 5:56882430:A | S1077* | stop_gained | 0.99 | 0 |
| 5:56815953:A | S127* | stop_gained | 0.99 | 0 |
| 5:56888258:A | C1430* | stop_gained | 0.99 | 0 |
| 5:56881573:G | Y791* | stop_gained | 0.99 | 0 |
| 5:56881573:A | Y791* | stop_gained | 0.99 | 0 |
| 5:56884718:T | R1292* | stop_gained | 0.99 | 0 |
| 5:56864746:T | R283* | stop_gained | 0.99 | 0 |
| 5:56882348:T | R1050* | stop_gained | 0.99 | 0 |
| 5:56881856:T | Q886* | stop_gained | 0.99 | 0 |
| 5:56881944:A | L915* | stop_gained | 0.99 | 0 |
| 5:56881944:G | L915* | stop_gained | 0.99 | 0 |
| 5:56856628:T | K171* | stop_gained | 0.99 | 0 |
| 5:56872654:A | C479* | stop_gained | 0.99 | 0 |
| 5:56815697:T | G42* | stop_gained | 0.99 | 0 |
| 5:56815743:A | W57* | stop_gained | 0.99 | 0 |
| 5:56881988:T | R930* | stop_gained | 0.99 | 0 |
| 5:56864913:G | Y338* | stop_gained | 0.99 | 0 |
| 5:56864913:A | Y338* | stop_gained | 0.99 | 0 |
| 5:56879087:A | C691* | stop_gained | 0.99 | 0 |
| 5:56881854:A | L885* | stop_gained | 0.99 | 0 |
| 5:56815997:T | E142* | stop_gained | 0.99 | 0 |
| 5:56875083:T | R580* | stop_gained | 0.99 | 0 |
| 5:56864761:T | R288* | stop_gained | 0.99 | 0 |
| 5:56882004:A | S935* | stop_gained | 0.99 | 0 |
| 5:56882004:G | S935* | stop_gained | 0.99 | 0 |
| 5:56881959:A | L920* | stop_gained | 0.99 | 0 |
| 5:56881248:G | S782* | stop_gained | 0.99 | 0 |
| 5:56881248:A | S782* | stop_gained | 0.99 | 0 |
| 5:56815658:T | G29* | stop_gained | 0.99 | 0 |
| 5:56882560:A | C1120* | stop_gained | 0.99 | 0 |
| 5:56882236:A | C1012* | stop_gained | 0.99 | 0 |
| 5:56881136:T | Q745* | stop_gained | 0.99 | 0 |
| 5:56856730:T | R205* | stop_gained | 0.99 | 0 |
| 5:56815889:T | Q106* | stop_gained | 0.99 | 0 |
| 5:56880753:A | C710* | stop_gained | 0.99 | 0 |
| 5:56881948:A | C916* | stop_gained | 0.99 | 0 |
| 5:56872703:T | R496* | stop_gained | 0.99 | 0 |
| 5:56881838:T | Q880* | stop_gained | 0.99 | 0 |
| 5:56888232:T | R1422* | stop_gained | 0.99 | 0 |
| 5:56816009:T | K146* | stop_gained | 0.99 | 0 |
| 5:56881907:T | E903* | stop_gained | 0.99 | 0 |
| 5:56859781:T | G234* | stop_gained | 0.99 | 0 |
| 5:56864842:T | R315* | stop_gained | 0.99 | 0 |
| 5:56881940:T | G914* | stop_gained | 0.99 | 0 |
| 5:56815949:T | E126* | stop_gained | 0.99 | 0 |
| 5:56881123:A | C740* | stop_gained | 0.99 | 0 |
| 5:56815848:A | S92* | stop_gained | 0.99 | 0 |
| 5:56815744:A | W57* | stop_gained | 0.99 | 0 |
| 5:56882561:T | R1121* | stop_gained | 0.99 | 0 |
| 5:56881180:A | C759* | stop_gained | 0.99 | 0 |
| 5:56879015:A | C667* | stop_gained | 0.99 | 0 |
| 5:56878989:T | R659* | stop_gained | 0.99 | 0 |
| 5:56886026:A | Y1359* | stop_gained | 0.99 | 0 |
| 5:56886026:G | Y1359* | stop_gained | 0.99 | 0 |
| 5:56816006:T | E145* | stop_gained | 0.99 | 0 |
| 5:56882468:T | K1090* | stop_gained | 0.99 | 0 |
| 5:56882299:A | C1033* | stop_gained | 0.99 | 0 |
| 5:56882473:A | C1091* | stop_gained | 0.99 | 0 |
| 5:56893639:T | R1500* | stop_gained | 0.99 | 0 |
| 5:56872690:A | C491* | stop_gained | 0.99 | 0 |
| 5:56882133:A | L978* | stop_gained | 0.99 | 0 |
| 5:56882133:G | L978* | stop_gained | 0.99 | 0 |
| 5:56865345:A | C347* | stop_gained | 0.99 | 0 |
| 5:56872865:T | R516* | stop_gained | 0.99 | 0 |
| 5:56875274:A | C643* | stop_gained | 0.99 | 0 |
| 5:56881830:A | L877* | stop_gained | 0.99 | 0 |
| 5:56815602:A | S10* | stop_gained | 0.99 | 0 |
| 5:56883631:A | C1257* | stop_gained | 0.99 | 0 |
| 5:56881660:G | Y820* | stop_gained | 0.99 | 0 |
| 5:56881660:A | Y820* | stop_gained | 0.99 | 0 |
| 5:56875298:A | Y651* | stop_gained | 0.99 | 0 |
| 5:56856696:A | C193* | stop_gained | 0.99 | 0 |
| 5:56865852:A | Y392* | stop_gained | 0.99 | 0 |
| 5:56865852:G | Y392* | stop_gained | 0.99 | 0 |
| 5:56875298:G | Y651* | stop_gained | 0.99 | 0 |
| 5:56815980:A | S136* | stop_gained | 0.99 | 0 |
| 5:56888246:A | Y1426* | stop_gained | 0.99 | 0 |
| 5:56888246:G | Y1426* | stop_gained | 0.99 | 0 |
| 5:56882491:A | C1097* | stop_gained | 0.99 | 0 |
| 5:56883571:G | Y1237* | stop_gained | 0.99 | 0 |
| 5:56883571:A | Y1237* | stop_gained | 0.99 | 0 |
| 5:56888279:A | C1437* | stop_gained | 0.99 | 0 |
| 5:56881222:G | Y773* | stop_gained | 0.99 | 0 |
| 5:56815836:A | S88* | stop_gained | 0.99 | 0 |
| 5:56815821:G | S83* | stop_gained | 0.99 | 0 |
| 5:56815821:A | S83* | stop_gained | 0.99 | 0 |
| 5:56815799:T | Q76* | stop_gained | 0.99 | 0 |
| 5:56881222:A | Y773* | stop_gained | 0.99 | 0 |
| 5:56815787:T | Q72* | stop_gained | 0.99 | 0 |
| 5:56871946:A | C446* | stop_gained | 0.99 | 0 |
| 5:56865351:A | C349* | stop_gained | 0.99 | 0 |
| 5:56884672:G | Y1276* | stop_gained | 0.99 | 0 |
| 5:56884672:A | Y1276* | stop_gained | 0.99 | 0 |
| 5:56872951:G | Y544* | stop_gained | 0.99 | 0 |
| 5:56872951:A | Y544* | stop_gained | 0.99 | 0 |
| 5:56884730:T | R1296* | stop_gained | 0.99 | 0 |
| 5:56872978:A | Y553* | stop_gained | 0.99 | 0 |
| 5:56884786:A | C1314* | stop_gained | 0.99 | 0 |
| 5:56864796:G | Y299* | stop_gained | 0.99 | 0 |
| 5:56864796:A | Y299* | stop_gained | 0.99 | 0 |
| 5:56884801:A | Y1319* | stop_gained | 0.99 | 0 |
| 5:56884801:G | Y1319* | stop_gained | 0.99 | 0 |
| 5:56871937:A | C443* | stop_gained | 0.99 | 0 |
| 5:56882148:A | L983* | stop_gained | 0.99 | 0 |
| 5:56872978:G | Y553* | stop_gained | 0.99 | 0 |
| 5:56885963:A | Y1338* | stop_gained | 0.99 | 0 |
| 5:56885963:G | Y1338* | stop_gained | 0.99 | 0 |
| 5:56881923:G | L908* | stop_gained | 0.99 | 0 |
| 5:56881923:A | L908* | stop_gained | 0.99 | 0 |
| 5:56881912:A | C904* | stop_gained | 0.99 | 0 |
| 5:56881879:G | Y893* | stop_gained | 0.99 | 0 |
| 5:56885996:A | Y1349* | stop_gained | 0.99 | 0 |
| 5:56885996:G | Y1349* | stop_gained | 0.99 | 0 |
| 5:56881879:A | Y893* | stop_gained | 0.99 | 0 |
| 5:56883634:G | Y1258* | stop_gained | 0.99 | 0 |
| 5:56883634:A | Y1258* | stop_gained | 0.99 | 0 |
| 5:56859764:G | L228* | stop_gained | 0.99 | 0 |
| 5:56859764:A | L228* | stop_gained | 0.99 | 0 |
| 5:56872720:A | Y501* | stop_gained | 0.99 | 0 |
| 5:56815667:T | K32* | stop_gained | 0.99 | 0 |
| 5:56881111:G | Y736* | stop_gained | 0.99 | 0 |
| 5:56815655:T | G28* | stop_gained | 0.99 | 0 |
| 5:56881111:A | Y736* | stop_gained | 0.99 | 0 |
| 5:56872681:A | C488* | stop_gained | 0.99 | 0 |
| 5:56815608:A | S12* | stop_gained | 0.99 | 0 |
| 5:56865369:A | C355* | stop_gained | 0.99 | 0 |
| 5:56879006:A | Y664* | stop_gained | 0.99 | 0 |
| 5:56879006:G | Y664* | stop_gained | 0.99 | 0 |
| 5:56872720:G | Y501* | stop_gained | 0.99 | 0 |
| 5:56815730:T | E53* | stop_gained | 0.99 | 0 |
| 5:56893605:A | C1488* | stop_gained | 0.99 | 0 |
| 5:56865456:A | E384E | splice_region_variant | 0.87 | 0 |
| 5:56856750:C | V211V | splice_region_variant | 0.82 | 0 |
| 5:56856750:A | V211V | splice_region_variant | 0.82 | 0 |
| 5:56856750:T | V211V | splice_region_variant | 0.82 | 0 |
| 5:56888357:A | K1463K | splice_region_variant | 0.82 | 0 |
| 5:56883679:A | Q1273Q | splice_region_variant | 0.82 | 0 |
| 5:56886062:G | K1371K | splice_region_variant | 0.79 | 0 |
| 5:56878982:G | K656K | splice_region_variant | 0.75 | 0 |
In silico saturation mutagenesis
| Cancer type | Selected cancer type | Mutational discovery Index | Feature Complexity |
|---|---|---|---|
| (BRCA) Breast adenocarcinoma | BRCA | 0.23 | 0.05 |