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Note: You're navigating the results of models obtained with IntOGen (2020). A new boostDM version is available here.
PIK3CA HNSC ×
Select a mutation to see further information
Mutation AA change Consequence type BoostDM score IntOGen frequency
3:179218303:A E545K missense_variant 1.00 36
3:179218294:A E542K missense_variant 1.00 21
3:179234297:G H1047R missense_variant 1.00 14
3:179234297:T H1047L missense_variant 1.00 5
3:179234284:G M1043V missense_variant 1.00 2
3:179218307:G Q546R missense_variant 1.00 2
3:179199088:A R88Q missense_variant 0.93 2
3:179210192:C C420R missense_variant 0.90 2
3:179221146:A E726K missense_variant 0.58 2
3:179218304:G E545G missense_variant 1.00 1
3:179218306:A Q546K missense_variant 1.00 1
3:179234298:A H1047Q missense_variant 0.99 1
3:179234277:A M1040I missense_variant 0.99 1
3:179210186:A E418K missense_variant 0.89 1
3:179210285:A G451R missense_variant 0.89 1
3:179210291:A E453K missense_variant 0.88 1
3:179199036:A V71I missense_variant 0.78 1
3:179204531:C G363A missense_variant 0.75 1
3:179203765:A N345K missense_variant 0.73 1
3:179199169:T R115L missense_variant 0.57 1
3:179218294:C E542Q missense_variant 1.00 0
3:179218303:C E545Q missense_variant 1.00 0
3:179218309:C E547Q missense_variant 1.00 0
3:179218309:A E547K missense_variant 1.00 0
3:179234286:C M1043I missense_variant 1.00 0
3:179234286:T M1043I missense_variant 1.00 0
3:179234286:A M1043I missense_variant 1.00 0
3:179218282:C D538H missense_variant 1.00 0
3:179218282:T D538Y missense_variant 1.00 0
3:179218280:C R537P missense_variant 1.00 0
3:179218280:A R537Q missense_variant 1.00 0
3:179218282:A D538N missense_variant 1.00 0
3:179218280:T R537L missense_variant 1.00 0
3:179234290:A D1045N missense_variant 1.00 0
3:179234290:C D1045H missense_variant 1.00 0
3:179234303:T G1049V missense_variant 1.00 0
3:179234290:T D1045Y missense_variant 1.00 0
3:179234303:C G1049A missense_variant 1.00 0
3:179234303:A G1049D missense_variant 1.00 0
3:179234302:T G1049C missense_variant 1.00 0
3:179234302:C G1049R missense_variant 1.00 0
3:179234302:A G1049S missense_variant 1.00 0
3:179234287:T N1044Y missense_variant 1.00 0
3:179234300:T H1048L missense_variant 1.00 0
3:179234300:G H1048R missense_variant 1.00 0
3:179234300:C H1048P missense_variant 1.00 0
3:179234291:T D1045V missense_variant 1.00 0
3:179234291:G D1045G missense_variant 1.00 0
3:179234291:C D1045A missense_variant 1.00 0
3:179234288:T N1044I missense_variant 1.00 0
3:179234288:G N1044S missense_variant 1.00 0
3:179234288:C N1044T missense_variant 1.00 0
3:179234287:G N1044D missense_variant 1.00 0
3:179234287:C N1044H missense_variant 1.00 0
3:179234284:T M1043L missense_variant 1.00 0
3:179234297:C H1047P missense_variant 1.00 0
3:179234284:C M1043L missense_variant 1.00 0
3:179234285:C M1043T missense_variant 1.00 0
3:179234285:G M1043R missense_variant 1.00 0
3:179234285:A M1043K missense_variant 1.00 0
3:179234293:T A1046S missense_variant 1.00 0
3:179234293:A A1046T missense_variant 1.00 0
3:179234293:C A1046P missense_variant 1.00 0
3:179234301:A H1048Q missense_variant 1.00 0
3:179234301:G H1048Q missense_variant 1.00 0
3:179218295:T E542V missense_variant 1.00 0
3:179218304:C E545A missense_variant 1.00 0
3:179218304:T E545V missense_variant 1.00 0
3:179218307:C Q546P missense_variant 1.00 0
3:179218307:T Q546L missense_variant 1.00 0
3:179218295:C E542A missense_variant 1.00 0
3:179218295:G E542G missense_variant 1.00 0
3:179218313:T K548I missense_variant 1.00 0
3:179218312:G K548E missense_variant 1.00 0
3:179218312:C K548Q missense_variant 1.00 0
3:179218310:T E547V missense_variant 1.00 0
3:179218310:G E547G missense_variant 1.00 0
3:179218310:C E547A missense_variant 1.00 0
3:179218313:C K548T missense_variant 1.00 0
3:179218313:G K548R missense_variant 1.00 0
3:179234282:T Q1042L missense_variant 1.00 0
3:179234282:C Q1042P missense_variant 1.00 0
3:179234278:C K1041Q missense_variant 1.00 0
3:179234278:G K1041E missense_variant 1.00 0
3:179234282:G Q1042R missense_variant 1.00 0
3:179234279:C K1041T missense_variant 1.00 0
3:179234279:T K1041I missense_variant 1.00 0
3:179234279:G K1041R missense_variant 1.00 0
3:179234275:C M1040L missense_variant 1.00 0
3:179234275:G M1040V missense_variant 1.00 0
3:179234275:T M1040L missense_variant 1.00 0
3:179218286:G P539R missense_variant 1.00 0
3:179218286:A P539H missense_variant 1.00 0
3:179218286:T P539L missense_variant 1.00 0
3:179218285:G P539A missense_variant 1.00 0
3:179218285:T P539S missense_variant 1.00 0
3:179218285:A P539T missense_variant 1.00 0
3:179218306:G Q546E missense_variant 1.00 0
3:179218298:G I543S missense_variant 1.00 0
3:179218298:C I543T missense_variant 1.00 0
3:179218298:A I543N missense_variant 1.00 0
3:179218291:A S541T missense_variant 1.00 0
3:179218289:A L540H missense_variant 1.00 0
3:179218289:G L540R missense_variant 1.00 0
3:179218291:G S541A missense_variant 1.00 0
3:179218291:C S541P missense_variant 1.00 0
3:179218289:C L540P missense_variant 1.00 0
3:179218300:G T544A missense_variant 0.99 0
3:179218300:T T544S missense_variant 0.99 0
3:179218300:C T544P missense_variant 0.99 0
3:179218297:C I543L missense_variant 0.99 0
3:179218297:G I543V missense_variant 0.99 0
3:179218297:T I543F missense_variant 0.99 0
3:179218283:T D538V missense_variant 0.99 0
3:179218283:C D538A missense_variant 0.99 0
3:179218283:G D538G missense_variant 0.99 0
3:179234311:G T1052A missense_variant 0.99 0
3:179234311:C T1052P missense_variant 0.99 0
3:179234311:T T1052S missense_variant 0.99 0
3:179234298:G H1047Q missense_variant 0.99 0
3:179234289:A N1044K missense_variant 0.99 0
3:179234289:G N1044K missense_variant 0.99 0
3:179218294:T E542* stop_gained 0.99 0
3:179218303:T E545* stop_gained 0.99 0
3:179234292:G D1045E missense_variant 0.99 0
3:179234292:A D1045E missense_variant 0.99 0
3:179218299:G I543M missense_variant 0.99 0
3:179234299:A H1048N missense_variant 0.99 0
3:179234299:G H1048D missense_variant 0.99 0
3:179234299:T H1048Y missense_variant 0.99 0
3:179218311:C E547D missense_variant 0.99 0
3:179218311:T E547D missense_variant 0.99 0
3:179234296:G H1047D missense_variant 0.99 0
3:179234296:A H1047N missense_variant 0.99 0
3:179234296:T H1047Y missense_variant 0.99 0
3:179218301:G T544S missense_variant 0.99 0
3:179218301:T T544I missense_variant 0.99 0
3:179218301:A T544N missense_variant 0.99 0
3:179218308:C Q546H missense_variant 0.99 0
3:179218308:T Q546H missense_variant 0.99 0
3:179218292:T S541F missense_variant 0.99 0
3:179218292:A S541Y missense_variant 0.99 0
3:179218292:G S541C missense_variant 0.99 0
3:179234277:T M1040I missense_variant 0.99 0
3:179234277:C M1040I missense_variant 0.99 0
3:179218309:T E547* stop_gained 0.99 0
3:179218296:T E542D missense_variant 0.99 0
3:179218296:C E542D missense_variant 0.99 0
3:179218305:C E545D missense_variant 0.99 0
3:179218305:T E545D missense_variant 0.99 0
3:179234283:T Q1042H missense_variant 0.99 0
3:179234283:C Q1042H missense_variant 0.99 0
3:179234280:C K1041N missense_variant 0.99 0
3:179234280:T K1041N missense_variant 0.99 0
3:179234309:T W1051L missense_variant 0.99 0
3:179234305:A G1050S missense_variant 0.99 0
3:179234305:C G1050R missense_variant 0.99 0
3:179234305:T G1050C missense_variant 0.99 0
3:179234306:A G1050D missense_variant 0.99 0
3:179234306:C G1050A missense_variant 0.99 0
3:179234306:T G1050V missense_variant 0.99 0
3:179234309:C W1051S missense_variant 0.99 0
3:179234310:C W1051C missense_variant 0.99 0
3:179234310:T W1051C missense_variant 0.99 0
3:179234276:C M1040T missense_variant 0.99 0
3:179234276:A M1040K missense_variant 0.99 0
3:179234276:G M1040R missense_variant 0.99 0
3:179234294:T A1046V missense_variant 0.99 0
3:179234281:G Q1042E missense_variant 0.99 0
3:179234281:A Q1042K missense_variant 0.99 0
3:179234294:A A1046E missense_variant 0.99 0
3:179234294:G A1046G missense_variant 0.99 0
3:179218284:A D538E missense_variant 0.99 0
3:179218284:G D538E missense_variant 0.99 0
3:179218288:G L540V missense_variant 0.98 0
3:179218288:A L540I missense_variant 0.98 0
3:179218288:T L540F missense_variant 0.98 0
3:179218279:G R537G missense_variant 0.98 0
3:179218312:T K548* stop_gained 0.98 0
3:179234312:A T1052K missense_variant 0.98 0
3:179234312:T T1052I missense_variant 0.98 0
3:179234312:G T1052R missense_variant 0.98 0
3:179234308:A W1051R missense_variant 0.98 0
3:179234308:G W1051G missense_variant 0.98 0
3:179234308:C W1051R missense_variant 0.98 0
3:179234278:T K1041* stop_gained 0.98 0
3:179218306:T Q546* stop_gained 0.97 0
3:179210193:C C420S missense_variant 0.97 0
3:179210193:T C420F missense_variant 0.97 0
3:179210193:A C420Y missense_variant 0.97 0
3:179198938:C R38P missense_variant 0.94 0
3:179198938:T R38L missense_variant 0.94 0
3:179198938:A R38H missense_variant 0.94 0
3:179198940:C E39Q missense_variant 0.94 0
3:179198940:A E39K missense_variant 0.94 0
3:179204576:T C378F missense_variant 0.94 0
3:179204576:C C378S missense_variant 0.94 0
3:179204576:A C378Y missense_variant 0.94 0
3:179199088:C R88P missense_variant 0.93 0
3:179199088:T R88L missense_variant 0.93 0
3:179234281:T Q1042* stop_gained 0.93 0
3:179218279:T R537* stop_gained 0.91 0
3:179210192:A C420S missense_variant 0.90 0
3:179210192:G C420G missense_variant 0.90 0
3:179234310:A W1051* stop_gained 0.90 0
3:179234309:A W1051* stop_gained 0.90 0
3:179210285:C G451R missense_variant 0.89 0
3:179209597:C W383S missense_variant 0.89 0
3:179209597:T W383L missense_variant 0.89 0
3:179209598:C W383C missense_variant 0.89 0
3:179209598:T W383C missense_variant 0.89 0
3:179209602:A E385K missense_variant 0.89 0
3:179209602:C E385Q missense_variant 0.89 0
3:179209606:C W386S missense_variant 0.89 0
3:179209606:T W386L missense_variant 0.89 0
3:179209607:C W386C missense_variant 0.89 0
3:179209607:T W386C missense_variant 0.89 0
3:179209617:A D390N missense_variant 0.89 0
3:179209617:C D390H missense_variant 0.89 0
3:179209617:T D390Y missense_variant 0.89 0
3:179209632:A D395N missense_variant 0.89 0
3:179209632:C D395H missense_variant 0.89 0
3:179209632:T D395Y missense_variant 0.89 0
3:179209642:A R398H missense_variant 0.89 0
3:179209642:C R398P missense_variant 0.89 0
3:179209642:T R398L missense_variant 0.89 0
3:179209647:A A400T missense_variant 0.89 0
3:179209647:C A400P missense_variant 0.89 0
3:179209647:T A400S missense_variant 0.89 0
3:179209657:A C403Y missense_variant 0.89 0
3:179209657:C C403S missense_variant 0.89 0
3:179209657:T C403F missense_variant 0.89 0
3:179210186:C E418Q missense_variant 0.89 0
3:179210201:A A423T missense_variant 0.89 0
3:179210201:C A423P missense_variant 0.89 0
3:179210201:T A423S missense_variant 0.89 0
3:179210205:C W424S missense_variant 0.89 0
3:179210205:T W424L missense_variant 0.89 0
3:179210206:C W424C missense_variant 0.89 0
3:179210206:T W424C missense_variant 0.89 0
3:179210207:A G425R missense_variant 0.89 0
3:179210207:C G425R missense_variant 0.89 0
3:179210208:A G425E missense_variant 0.89 0
3:179210208:C G425A missense_variant 0.89 0
3:179210208:T G425V missense_variant 0.89 0
3:179210225:A D431N missense_variant 0.89 0
3:179210225:C D431H missense_variant 0.89 0
3:179210225:T D431Y missense_variant 0.89 0
3:179210243:A V437I missense_variant 0.89 0
3:179210243:C V437L missense_variant 0.89 0
3:179210243:T V437L missense_variant 0.89 0
3:179210258:A A442T missense_variant 0.89 0
3:179210258:C A442P missense_variant 0.89 0
3:179210258:T A442S missense_variant 0.89 0
3:179210271:C W446S missense_variant 0.89 0
3:179210271:T W446L missense_variant 0.89 0
3:179210272:C W446C missense_variant 0.89 0
3:179210272:T W446C missense_variant 0.89 0
3:179210276:A V448I missense_variant 0.89 0
3:179210276:C V448L missense_variant 0.89 0
3:179210276:T V448L missense_variant 0.89 0
3:179210468:A S481N missense_variant 0.89 0
3:179210468:C S481T missense_variant 0.89 0
3:179210468:T S481I missense_variant 0.89 0
3:179198942:C E39D missense_variant 0.89 0
3:179198942:T E39D missense_variant 0.89 0
3:179210322:C G463A missense_variant 0.88 0
3:179210322:T G463V missense_variant 0.88 0
3:179210431:A E469K missense_variant 0.88 0
3:179210431:C E469Q missense_variant 0.88 0
3:179210441:A C472Y missense_variant 0.88 0
3:179210441:C C472S missense_variant 0.88 0
3:179210441:T C472F missense_variant 0.88 0
3:179210321:A G463R missense_variant 0.88 0
3:179210322:A G463E missense_variant 0.88 0
3:179210313:C G460A missense_variant 0.88 0
3:179210313:T G460V missense_variant 0.88 0
3:179210315:A V461I missense_variant 0.88 0
3:179210315:C V461L missense_variant 0.88 0
3:179210315:T V461F missense_variant 0.88 0
3:179210321:C G463R missense_variant 0.88 0
3:179210452:C E476Q missense_variant 0.88 0
3:179210286:A G451E missense_variant 0.88 0
3:179210286:C G451A missense_variant 0.88 0
3:179210286:T G451V missense_variant 0.88 0
3:179210452:A E476K missense_variant 0.88 0
3:179210291:C E453Q missense_variant 0.88 0
3:179210294:A D454N missense_variant 0.88 0
3:179210294:C D454H missense_variant 0.88 0
3:179210294:T D454Y missense_variant 0.88 0
3:179210312:A G460S missense_variant 0.88 0
3:179210312:C G460R missense_variant 0.88 0
3:179210312:T G460C missense_variant 0.88 0
3:179210313:A G460D missense_variant 0.88 0
3:179204575:A C378S missense_variant 0.86 0
3:179204575:C C378R missense_variant 0.86 0
3:179204575:G C378G missense_variant 0.86 0
3:179199094:T C90F missense_variant 0.86 0
3:179199094:C C90S missense_variant 0.86 0
3:179199094:A C90Y missense_variant 0.86 0
3:179198979:C E52Q missense_variant 0.78 0
3:179198979:A E52K missense_variant 0.78 0
3:179198967:C E48Q missense_variant 0.78 0
3:179198967:A E48K missense_variant 0.78 0
3:179198943:T A40S missense_variant 0.78 0
3:179198943:C A40P missense_variant 0.78 0
3:179198943:A A40T missense_variant 0.78 0
3:179198932:T C36F missense_variant 0.78 0
3:179198928:A E35K missense_variant 0.78 0
3:179198932:C C36S missense_variant 0.78 0
3:179198932:A C36Y missense_variant 0.78 0
3:179198928:C E35Q missense_variant 0.78 0
3:179199063:C E80Q missense_variant 0.78 0
3:179199063:A E80K missense_variant 0.78 0
3:179199061:T R79M missense_variant 0.78 0
3:179199061:C R79T missense_variant 0.78 0
3:179199061:A R79K missense_variant 0.78 0
3:179199057:C E78Q missense_variant 0.78 0
3:179199057:A E78K missense_variant 0.78 0
3:179199042:T V73F missense_variant 0.78 0
3:179199042:C V73L missense_variant 0.78 0
3:179199042:A V73I missense_variant 0.78 0
3:179199040:T S72I missense_variant 0.78 0
3:179199040:C S72T missense_variant 0.78 0
3:179199040:A S72N missense_variant 0.78 0
3:179199036:T V71L missense_variant 0.78 0
3:179199036:C V71L missense_variant 0.78 0
3:179199018:C E65Q missense_variant 0.78 0
3:179199018:A E65K missense_variant 0.78 0
3:179199015:T D64Y missense_variant 0.78 0
3:179199015:C D64H missense_variant 0.78 0
3:179199015:A D64N missense_variant 0.78 0
3:179198986:T R54I missense_variant 0.78 0
3:179198986:C R54T missense_variant 0.78 0
3:179198986:A R54K missense_variant 0.78 0
3:179198982:T A53S missense_variant 0.78 0
3:179198982:C A53P missense_variant 0.78 0
3:179198982:A A53T missense_variant 0.78 0
3:179199051:A E76K missense_variant 0.77 0
3:179199096:T D91Y missense_variant 0.77 0
3:179199096:C D91H missense_variant 0.77 0
3:179199096:A D91N missense_variant 0.77 0
3:179199051:C E76Q missense_variant 0.77 0
3:179198937:G R38G missense_variant 0.76 0
3:179198937:T R38C missense_variant 0.76 0
3:179198937:A R38S missense_variant 0.76 0
3:179204509:T V356F missense_variant 0.75 0
3:179204509:C V356L missense_variant 0.75 0
3:179204509:A V356I missense_variant 0.75 0
3:179204588:T R382M missense_variant 0.75 0
3:179204588:C R382T missense_variant 0.75 0
3:179204588:A R382K missense_variant 0.75 0
3:179204569:T V376L missense_variant 0.75 0
3:179204569:C V376L missense_variant 0.75 0
3:179204569:A V376I missense_variant 0.75 0
3:179204567:T R375I missense_variant 0.75 0
3:179204567:C R375T missense_variant 0.75 0
3:179204519:C G359A missense_variant 0.75 0
3:179204519:A G359D missense_variant 0.75 0
3:179204518:T G359C missense_variant 0.75 0
3:179204518:C G359R missense_variant 0.75 0
3:179204518:A G359S missense_variant 0.75 0
3:179204513:T R357L missense_variant 0.75 0
3:179204513:C R357P missense_variant 0.75 0
3:179204513:A R357Q missense_variant 0.75 0
3:179204567:A R375K missense_variant 0.75 0
3:179204554:T V371L missense_variant 0.75 0
3:179204554:C V371L missense_variant 0.75 0
3:179204554:A V371M missense_variant 0.75 0
3:179204548:T D369Y missense_variant 0.75 0
3:179204548:C D369H missense_variant 0.75 0
3:179204548:A D369N missense_variant 0.75 0
3:179204546:T C368F missense_variant 0.75 0
3:179204546:C C368S missense_variant 0.75 0
3:179204546:A C368Y missense_variant 0.75 0
3:179204536:C E365Q missense_variant 0.75 0
3:179204536:A E365K missense_variant 0.75 0
3:179204533:C G364R missense_variant 0.75 0
3:179204533:A G364R missense_variant 0.75 0
3:179204531:T G363V missense_variant 0.75 0
3:179204531:A G363E missense_variant 0.75 0
3:179204530:C G363R missense_variant 0.75 0
3:179204530:A G363R missense_variant 0.75 0
3:179204519:T G359V missense_variant 0.75 0
3:179209690:C G414A missense_variant 0.75 0
3:179209681:A G411D missense_variant 0.75 0
3:179209681:C G411A missense_variant 0.75 0
3:179209689:T G414C missense_variant 0.75 0
3:179209669:A C407Y missense_variant 0.75 0
3:179209681:T G411V missense_variant 0.75 0
3:179209698:C E417Q missense_variant 0.75 0
3:179209698:A E417K missense_variant 0.75 0
3:179209690:T G414V missense_variant 0.75 0
3:179209690:A G414D missense_variant 0.75 0
3:179209669:C C407S missense_variant 0.75 0
3:179209669:T C407F missense_variant 0.75 0
3:179209674:C V409L missense_variant 0.75 0
3:179209674:A V409I missense_variant 0.75 0
3:179209684:T R412L missense_variant 0.75 0
3:179209684:C R412P missense_variant 0.75 0
3:179209684:A R412Q missense_variant 0.75 0
3:179209674:T V409F missense_variant 0.75 0
3:179209689:C G414R missense_variant 0.75 0
3:179209689:A G414S missense_variant 0.75 0
3:179209680:A G411S missense_variant 0.75 0
3:179209680:C G411R missense_variant 0.75 0
3:179209680:T G411C missense_variant 0.75 0
3:179203765:G N345K missense_variant 0.73 0
3:179198941:T E39V missense_variant 0.69 0
3:179198941:C E39A missense_variant 0.69 0
3:179198941:G E39G missense_variant 0.69 0
3:179234242:T D1029Y missense_variant 0.67 0
3:179234242:C D1029H missense_variant 0.67 0
3:179234242:A D1029N missense_variant 0.67 0
3:179230306:A L956M missense_variant 0.62 0
3:179230306:G L956V missense_variant 0.62 0
3:179199743:C V136L missense_variant 0.58 0
3:179199743:A V136I missense_variant 0.58 0
3:179199740:C E135Q missense_variant 0.58 0
3:179199740:A E135K missense_variant 0.58 0
3:179199734:T D133Y missense_variant 0.58 0
3:179199734:C D133H missense_variant 0.58 0
3:179199734:A D133N missense_variant 0.58 0
3:179199728:T V131F missense_variant 0.58 0
3:179199728:C V131L missense_variant 0.58 0
3:179199728:A V131I missense_variant 0.58 0
3:179199722:T D129Y missense_variant 0.58 0
3:179199722:C D129H missense_variant 0.58 0
3:179199722:A D129N missense_variant 0.58 0
3:179218217:A R516K missense_variant 0.58 0
3:179218217:T R516I missense_variant 0.58 0
3:179218222:A A518T missense_variant 0.58 0
3:179218222:C A518P missense_variant 0.58 0
3:179218222:T A518S missense_variant 0.58 0
3:179218226:A R519K missense_variant 0.58 0
3:179218226:C R519T missense_variant 0.58 0
3:179218226:T R519I missense_variant 0.58 0
3:179218228:A D520N missense_variant 0.58 0
3:179218228:C D520H missense_variant 0.58 0
3:179218228:T D520Y missense_variant 0.58 0
3:179199899:T G188W missense_variant 0.58 0
3:179199899:C G188R missense_variant 0.58 0
3:179199899:A G188R missense_variant 0.58 0
3:179199893:T D186Y missense_variant 0.58 0
3:179199893:C D186H missense_variant 0.58 0
3:179199893:A D186N missense_variant 0.58 0
3:179199863:C E176Q missense_variant 0.58 0
3:179199863:A E176K missense_variant 0.58 0
3:179199851:C E172Q missense_variant 0.58 0
3:179199851:A E172K missense_variant 0.58 0
3:179199833:T V166F missense_variant 0.58 0
3:179199833:C V166L missense_variant 0.58 0
3:179199833:A V166I missense_variant 0.58 0
3:179199824:T A163S missense_variant 0.58 0
3:179199824:C A163P missense_variant 0.58 0
3:179199824:A A163T missense_variant 0.58 0
3:179199819:T S161I missense_variant 0.58 0
3:179199819:C S161T missense_variant 0.58 0
3:179199819:A S161N missense_variant 0.58 0
3:179199798:T R154M missense_variant 0.58 0
3:179199798:C R154T missense_variant 0.58 0
3:179199798:A R154K missense_variant 0.58 0
3:179199791:T D152Y missense_variant 0.58 0
3:179199791:C D152H missense_variant 0.58 0
3:179199791:A D152N missense_variant 0.58 0
3:179199788:T V151L missense_variant 0.58 0
3:179199788:C V151L missense_variant 0.58 0
3:179199788:A V151M missense_variant 0.58 0
3:179199782:C E149Q missense_variant 0.58 0
3:179199782:A E149K missense_variant 0.58 0
3:179199777:T C147F missense_variant 0.58 0
3:179199777:C C147S missense_variant 0.58 0
3:179199777:A C147Y missense_variant 0.58 0
3:179199773:T V146F missense_variant 0.58 0
3:179199773:C V146L missense_variant 0.58 0
3:179199773:A V146I missense_variant 0.58 0
3:179221086:A V706I missense_variant 0.58 0
3:179221086:C V706L missense_variant 0.58 0
3:179221086:T V706F missense_variant 0.58 0
3:179221089:A E707K missense_variant 0.58 0
3:179221089:C E707Q missense_variant 0.58 0
3:179221092:A A708T missense_variant 0.58 0
3:179221092:C A708P missense_variant 0.58 0
3:179221092:T A708S missense_variant 0.58 0
3:179221097:A M709I missense_variant 0.58 0
3:179221097:C M709I missense_variant 0.58 0
3:179221097:T M709I missense_variant 0.58 0
3:179221098:A E710K missense_variant 0.58 0
3:179221098:C E710Q missense_variant 0.58 0
3:179221119:A D717N missense_variant 0.58 0
3:179221119:C D717H missense_variant 0.58 0
3:179221119:T D717Y missense_variant 0.58 0
3:179221134:A E722K missense_variant 0.58 0
3:179221134:C E722Q missense_variant 0.58 0
3:179221143:A D725N missense_variant 0.58 0
3:179221143:C D725H missense_variant 0.58 0
3:179221143:T D725Y missense_variant 0.58 0
3:179199756:T R140L missense_variant 0.58 0
3:179221146:C E726Q missense_variant 0.58 0
3:179221157:C K729N missense_variant 0.58 0
3:179221157:T K729N missense_variant 0.58 0
3:179199756:C R140P missense_variant 0.58 0
3:179199756:A R140Q missense_variant 0.58 0
3:179199749:T D138Y missense_variant 0.58 0
3:179199749:C D138H missense_variant 0.58 0
3:179199749:A D138N missense_variant 0.58 0
3:179199743:T V136L missense_variant 0.58 0
3:179210476:A V484I missense_variant 0.58 0
3:179210476:C V484L missense_variant 0.58 0
3:179210476:T V484L missense_variant 0.58 0
3:179210488:A D488N missense_variant 0.58 0
3:179210488:C D488H missense_variant 0.58 0
3:179210488:T D488Y missense_variant 0.58 0
3:179210503:A E493K missense_variant 0.58 0
3:179210503:C E493Q missense_variant 0.58 0
3:179210506:A E494K missense_variant 0.58 0
3:179210506:C E494Q missense_variant 0.58 0
3:179210512:A A496T missense_variant 0.58 0
3:179210512:C A496P missense_variant 0.58 0
3:179210512:T A496S missense_variant 0.58 0
3:179210531:A R502Q missense_variant 0.58 0
3:179210531:C R502P missense_variant 0.58 0
3:179210531:T R502L missense_variant 0.58 0
3:179210533:A E503K missense_variant 0.58 0
3:179210533:C E503Q missense_variant 0.58 0
3:179210539:A G505R missense_variant 0.58 0
3:179210539:C G505R missense_variant 0.58 0
3:179210540:A G505E missense_variant 0.58 0
3:179210540:C G505A missense_variant 0.58 0
3:179210540:T G505V missense_variant 0.58 0
3:179218217:C R516T missense_variant 0.58 0
3:179199169:C R115P missense_variant 0.57 0
3:179199169:A R115Q missense_variant 0.57 0
3:179230307:G L956W missense_variant 0.57 0
3:179230307:C L956S missense_variant 0.57 0
3:179199177:T G118C missense_variant 0.56 0
3:179199177:C G118R missense_variant 0.56 0
3:179199177:A G118S missense_variant 0.56 0
3:179199087:G R88G missense_variant 0.56 0
3:179199714:A C126Y missense_variant 0.55 0
3:179199714:T C126F missense_variant 0.55 0
3:179199716:A E127K missense_variant 0.55 0
3:179199716:C E127Q missense_variant 0.55 0
3:179199706:C M123I missense_variant 0.55 0
3:179199706:T M123I missense_variant 0.55 0
3:179199714:C C126S missense_variant 0.55 0
3:179199690:A G118D missense_variant 0.55 0
3:179199690:C G118A missense_variant 0.55 0
3:179199690:T G118V missense_variant 0.55 0
3:179199695:A A120T missense_variant 0.55 0
3:179199695:C A120P missense_variant 0.55 0
3:179199695:T A120S missense_variant 0.55 0
3:179199701:A G122S missense_variant 0.55 0
3:179199701:C G122R missense_variant 0.55 0
3:179199701:T G122C missense_variant 0.55 0
3:179199702:A G122D missense_variant 0.55 0
3:179199702:C G122A missense_variant 0.55 0
3:179199702:T G122V missense_variant 0.55 0
3:179199706:A M123I missense_variant 0.55 0
3:179210194:G C420W missense_variant 0.54 0
3:179199095:G C90W missense_variant 0.54 0
3:179204577:G C378W missense_variant 0.51 0
In silico saturation mutagenesis
Alt text Show figure caption
Cancer type Selected cancer type Mutational discovery Index Feature Complexity
(HNSC) Head and neck squamous cell carcinoma HNSC 0.64 0.19