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Note: You're navigating the results of models obtained with IntOGen (2020). A new boostDM version is available here.
RHOA ST ×
Select a mutation to see further information
Mutation AA change Consequence type BoostDM score IntOGen frequency
3:49368520:T G62E missense_variant 1.00 3
3:49375465:C Y42C missense_variant 1.00 3
3:49368521:T G62R missense_variant 1.00 2
3:49375465:G Y42S missense_variant 1.00 2
3:49375474:C F39C missense_variant 1.00 2
3:49368536:C L57V missense_variant 0.98 2
3:49368523:T A61D missense_variant 0.93 2
3:49375577:A R5W missense_variant 0.75 2
3:49375472:T E40K missense_variant 1.00 1
3:49375467:C N41K missense_variant 1.00 1
3:49368530:A D59Y missense_variant 1.00 1
3:49375513:A S26I missense_variant 0.99 1
3:49375576:T R5Q missense_variant 0.99 1
3:49368526:T T60K missense_variant 0.93 1
3:49375540:T G17E missense_variant 0.77 1
3:49375489:C Y34C missense_variant 0.65 1
3:49368500:T L69M missense_variant 0.54 1
3:49375472:G E40Q missense_variant 1.00 0
3:49375467:T N41K missense_variant 1.00 0
3:49368530:T D59N missense_variant 1.00 0
3:49368530:G D59H missense_variant 1.00 0
3:49368520:G G62A missense_variant 1.00 0
3:49368521:A G62W missense_variant 1.00 0
3:49368521:G G62R missense_variant 1.00 0
3:49368524:A A61S missense_variant 1.00 0
3:49368524:G A61P missense_variant 1.00 0
3:49368524:T A61T missense_variant 1.00 0
3:49368520:A G62V missense_variant 1.00 0
3:49375465:A Y42F missense_variant 1.00 0
3:49375468:A N41I missense_variant 1.00 0
3:49375469:G N41H missense_variant 1.00 0
3:49375469:C N41D missense_variant 1.00 0
3:49375469:A N41Y missense_variant 1.00 0
3:49375468:G N41T missense_variant 1.00 0
3:49375468:C N41S missense_variant 1.00 0
3:49375473:C F39L missense_variant 1.00 0
3:49375473:T F39L missense_variant 1.00 0
3:49375471:A E40V missense_variant 1.00 0
3:49375471:G E40A missense_variant 1.00 0
3:49375471:C E40G missense_variant 1.00 0
3:49375470:G E40D missense_variant 1.00 0
3:49375470:A E40D missense_variant 1.00 0
3:49375466:T Y42N missense_variant 1.00 0
3:49375466:G Y42H missense_variant 1.00 0
3:49375466:C Y42D missense_variant 1.00 0
3:49375475:T F39I missense_variant 1.00 0
3:49375474:T F39Y missense_variant 1.00 0
3:49375474:G F39S missense_variant 1.00 0
3:49375475:G F39L missense_variant 1.00 0
3:49375475:C F39V missense_variant 1.00 0
3:49375472:A E40* stop_gained 1.00 0
3:49375513:G S26T missense_variant 0.99 0
3:49375513:T S26N missense_variant 0.99 0
3:49375576:G R5P missense_variant 0.99 0
3:49375576:A R5L missense_variant 0.99 0
3:49375451:G E47Q missense_variant 0.98 0
3:49375451:T E47K missense_variant 0.98 0
3:49368536:T L57M missense_variant 0.98 0
3:49368527:G T60P missense_variant 0.97 0
3:49368527:A T60S missense_variant 0.97 0
3:49368527:C T60A missense_variant 0.97 0
3:49368529:A D59V missense_variant 0.97 0
3:49368529:C D59G missense_variant 0.97 0
3:49368529:G D59A missense_variant 0.97 0
3:49375514:C S26G missense_variant 0.96 0
3:49375514:A S26C missense_variant 0.96 0
3:49375514:G S26R missense_variant 0.96 0
3:49375487:A V35L missense_variant 0.95 0
3:49375478:G V38L missense_variant 0.95 0
3:49375487:T V35M missense_variant 0.95 0
3:49375478:A V38L missense_variant 0.95 0
3:49375478:T V38M missense_variant 0.95 0
3:49375487:G V35L missense_variant 0.95 0
3:49375512:T S26R missense_variant 0.95 0
3:49375512:C S26R missense_variant 0.95 0
3:49368528:C D59E missense_variant 0.95 0
3:49368528:T D59E missense_variant 0.95 0
3:49368534:A L57F missense_variant 0.95 0
3:49368534:G L57F missense_variant 0.95 0
3:49368526:A T60I missense_variant 0.93 0
3:49368526:C T60R missense_variant 0.93 0
3:49368523:A A61V missense_variant 0.93 0
3:49368523:C A61G missense_variant 0.93 0
3:49368535:C L57W missense_variant 0.92 0
3:49368535:G L57S missense_variant 0.92 0
3:49368531:G W58C missense_variant 0.87 0
3:49368532:A W58L missense_variant 0.87 0
3:49368532:G W58S missense_variant 0.87 0
3:49368496:G R70T missense_variant 0.87 0
3:49368479:T D76N missense_variant 0.87 0
3:49368479:G D76H missense_variant 0.87 0
3:49368502:A R68L missense_variant 0.87 0
3:49368502:G R68P missense_variant 0.87 0
3:49368502:T R68H missense_variant 0.87 0
3:49368506:A D67Y missense_variant 0.87 0
3:49368506:G D67H missense_variant 0.87 0
3:49368506:T D67N missense_variant 0.87 0
3:49368512:A D65Y missense_variant 0.87 0
3:49368512:G D65H missense_variant 0.87 0
3:49368512:T D65N missense_variant 0.87 0
3:49368515:G E64Q missense_variant 0.87 0
3:49368515:T E64K missense_variant 0.87 0
3:49368479:A D76Y missense_variant 0.87 0
3:49368473:T D78N missense_variant 0.87 0
3:49368473:G D78H missense_variant 0.87 0
3:49368473:A D78Y missense_variant 0.87 0
3:49368470:T V79I missense_variant 0.87 0
3:49368470:G V79L missense_variant 0.87 0
3:49368470:A V79F missense_variant 0.87 0
3:49368428:T E93K missense_variant 0.87 0
3:49368428:G E93Q missense_variant 0.87 0
3:49368531:A W58C missense_variant 0.87 0
3:49368548:G V53L missense_variant 0.87 0
3:49368548:T V53I missense_variant 0.87 0
3:49368496:A R70M missense_variant 0.87 0
3:49368496:T R70K missense_variant 0.87 0
3:49368545:G E54Q missense_variant 0.87 0
3:49368545:T E54K missense_variant 0.87 0
3:49368548:A V53L missense_variant 0.87 0
3:49375451:A E47* stop_gained 0.83 0
3:49375531:T C20Y missense_variant 0.77 0
3:49375531:G C20S missense_variant 0.77 0
3:49375531:A C20F missense_variant 0.77 0
3:49375586:T A2T missense_variant 0.77 0
3:49375540:A G17V missense_variant 0.77 0
3:49375540:G G17A missense_variant 0.77 0
3:49375541:G G17R missense_variant 0.77 0
3:49375541:T G17R missense_variant 0.77 0
3:49375543:A C16F missense_variant 0.77 0
3:49375543:G C16S missense_variant 0.77 0
3:49375543:T C16Y missense_variant 0.77 0
3:49375547:A A15S missense_variant 0.77 0
3:49375547:G A15P missense_variant 0.77 0
3:49375547:T A15T missense_variant 0.77 0
3:49375549:A G14V missense_variant 0.77 0
3:49375549:G G14A missense_variant 0.77 0
3:49375549:T G14E missense_variant 0.77 0
3:49375550:G G14R missense_variant 0.77 0
3:49375550:T G14R missense_variant 0.77 0
3:49375553:A D13Y missense_variant 0.77 0
3:49375553:G D13H missense_variant 0.77 0
3:49375553:T D13N missense_variant 0.77 0
3:49375555:A G12V missense_variant 0.77 0
3:49375555:G G12A missense_variant 0.77 0
3:49375555:T G12D missense_variant 0.77 0
3:49375556:A G12C missense_variant 0.77 0
3:49375556:G G12R missense_variant 0.77 0
3:49375556:T G12S missense_variant 0.77 0
3:49375559:A V11F missense_variant 0.77 0
3:49375559:G V11L missense_variant 0.77 0
3:49375559:T V11I missense_variant 0.77 0
3:49375565:A V9L missense_variant 0.77 0
3:49375565:G V9L missense_variant 0.77 0
3:49375565:T V9M missense_variant 0.77 0
3:49375583:A A3S missense_variant 0.77 0
3:49375583:G A3P missense_variant 0.77 0
3:49375583:T A3T missense_variant 0.77 0
3:49375586:A A2S missense_variant 0.77 0
3:49375586:G A2P missense_variant 0.77 0
3:49375577:C R5G missense_variant 0.75 0
3:49360271:A A174S missense_variant 0.75 0
3:49360271:G A174P missense_variant 0.75 0
3:49360271:T A174T missense_variant 0.75 0
3:49375448:A V48L missense_variant 0.73 0
3:49375445:G D49H missense_variant 0.73 0
3:49375460:G A44P missense_variant 0.73 0
3:49375460:A A44S missense_variant 0.73 0
3:49375457:T D45N missense_variant 0.73 0
3:49375457:G D45H missense_variant 0.73 0
3:49375457:A D45Y missense_variant 0.73 0
3:49375445:A D49Y missense_variant 0.73 0
3:49375448:T V48M missense_variant 0.73 0
3:49375448:G V48L missense_variant 0.73 0
3:49375445:T D49N missense_variant 0.73 0
3:49375460:T A44T missense_variant 0.73 0
3:49368535:T L57* stop_gained 0.73 0
3:49360222:T C190Y missense_variant 0.71 0
3:49360222:A C190F missense_variant 0.71 0
3:49360222:G C190S missense_variant 0.71 0
3:49375464:C Y42* stop_gained 0.70 0
3:49375464:T Y42* stop_gained 0.70 0
3:49360313:G S160P missense_variant 0.68 0
3:49360313:T S160T missense_variant 0.68 0
3:49360313:C S160A missense_variant 0.68 0
3:49368448:C I86S missense_variant 0.68 0
3:49368448:G I86T missense_variant 0.68 0
3:49368448:T I86N missense_variant 0.68 0
3:49360331:T F154I missense_variant 0.68 0
3:49360331:G F154L missense_variant 0.68 0
3:49360331:C F154V missense_variant 0.68 0
3:49375489:G Y34S missense_variant 0.65 0
3:49375489:A Y34F missense_variant 0.65 0
3:49375481:G T37P missense_variant 0.64 0
3:49375481:C T37A missense_variant 0.64 0
3:49375481:A T37S missense_variant 0.64 0
3:49362578:A N109I missense_variant 0.55 0
3:49360237:G K185T missense_variant 0.55 0
3:49360237:C K185R missense_variant 0.55 0
3:49360237:A K185M missense_variant 0.55 0
3:49360234:C K186R missense_variant 0.55 0
3:49360234:A K186I missense_variant 0.55 0
3:49360234:G K186T missense_variant 0.55 0
3:49362578:G N109T missense_variant 0.55 0
3:49362578:C N109S missense_variant 0.55 0
3:49360265:C R176G missense_variant 0.55 0
3:49375441:A G50V missense_variant 0.54 0
3:49368539:T A56T missense_variant 0.54 0
3:49368449:A I86F missense_variant 0.54 0
3:49368449:C I86V missense_variant 0.54 0
3:49368449:G I86L missense_variant 0.54 0
3:49368539:A A56S missense_variant 0.54 0
3:49360330:C F154C missense_variant 0.54 0
3:49375441:T G50E missense_variant 0.54 0
3:49375441:G G50A missense_variant 0.54 0
3:49360330:G F154S missense_variant 0.54 0
3:49360330:T F154Y missense_variant 0.54 0
3:49360342:A R150M missense_variant 0.54 0
3:49360342:G R150T missense_variant 0.54 0
3:49360342:T R150K missense_variant 0.54 0
3:49362521:A R128M missense_variant 0.54 0
3:49360236:G K185N missense_variant 0.54 0
3:49360236:A K185N missense_variant 0.54 0
3:49368539:G A56P missense_variant 0.54 0
3:49362521:T R128K missense_variant 0.54 0
3:49362521:G R128T missense_variant 0.54 0
3:49375463:T V43M missense_variant 0.54 0
3:49375463:A V43L missense_variant 0.54 0
3:49375463:G V43L missense_variant 0.54 0
3:49368500:C L69V missense_variant 0.54 0
3:49362550:G K118N missense_variant 0.53 0
3:49362550:A K118N missense_variant 0.53 0
3:49375506:C D28E missense_variant 0.53 0
3:49375506:T D28E missense_variant 0.53 0
3:49360246:A R182I missense_variant 0.53 0
3:49360246:T R182K missense_variant 0.53 0
3:49360246:G R182T missense_variant 0.53 0
3:49375500:C F30L missense_variant 0.52 0
3:49375500:T F30L missense_variant 0.52 0
3:49362540:C R122G missense_variant 0.51 0
3:49362540:A R122W missense_variant 0.51 0
3:49362586:T F106L missense_variant 0.51 0
3:49362586:C F106L missense_variant 0.51 0
In silico saturation mutagenesis
Alt text Show figure caption
Cancer type Selected cancer type Mutational discovery Index Feature Complexity
(ST) Stomach adenocarcinoma ST 0.68 0.14