Barcelona Biomedical Genomics Lab

BBGLab is a research group integrated in the Institute for Research Biomedicine (IRB) in Barcelona, which is part of the Barcelona Institute of Science and Technology (BIST). The lab is located at the Barcelona Science Park (Parc Científic de Barcelona).

Our research is focused on the study of cancer from a genomics perspective. We are particularly interested in the identification of cancer driver mutations, genes and pathways across tumour types and in the study of their potential as therapeutic targets. See details in our group site.

BoostDM team

BoostDM has been developed by a team of scientists and engineers working in the Biomedical Genomics lab at the Institute for Research in Biomedicine (IRB Barcelona). Ferran Muiños, Francisco Martinez-Jimenez, Oriol Pich, Abel Gonzalez-Perez and Nuria Lopez-Bigas led the main conceptualization, development and validation of the method.

Latest release (2024.09.20)

Developers

Federica Brando
Miguel L. Grau
Ferran Muiños
Joan E. Ramis-Zaldívar

Others

Santiago Demajo
Paula Gomis
Stefano Pellegrini
Mònica Sánchez-Guixé

Abel Gonzalez-Perez
Nuria Lopez-Bigas

BoostDM Legacy

Developers

Francisco Martínez Jimenez
Loris Mularoni
Oriol Pich
Iker Reyes-Salazar

Others

Claudia Arnedo-Pac
David Martínez Millán
Electra Tapanari

Citation

Muiños, F., Martínez-Jiménez, F., Pich, O., Gonzalez-Perez, A. & Lopez-Bigas, N.
In silico saturation mutagenesis of cancer genes. Nature 596, 428-432 (2021).
DOI: 10.1038/s41586-021-03771-1

Watch the video of boostDM: boostDM: score all possible point mutations

Contact

For information, comments and/or suggestions, please contact us at: bbglab@irbbarcelona.org

Find all contact details in our site.