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CDKN2A 9:21971044:T (D105E) × CSCC ×
Driver potential information
Model BoostDM class BoostDM score
(CSCC) Cutaneous Squamous Cell Carcinoma Passenger 0.05
Feature importance

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Feature Feature value SHAP value
Linear Clustering Score (LCS) 0.00 -1.16 High negative
3D Clustering in Cancer Type (3CT) 1.00 0.57 Medium positive
Recurrent in PFAM Domain (DOM) 0.00 0.00 Non-significant
PhyloP 100-way Score (PHYLOP) -0.67 -0.46 Medium negative
Stop Codon in Last Exon (NMD) 0.00 0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Methylation (METHYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Phosphorylation (PHOS) 0.00 0.00 Non-significant
Post-translational Modification Site: Regulatory site (REG) 0.00 0.00 Non-significant
Post-translational Modification Site: Ubiquitination (UB) 0.00 0.00 Non-significant
Consequence Type: Missense (MISSENSE) 1.00 -0.03 Non-significant
Consequence Type: Nonsense (NONSENSE) 0.00 -0.20 Medium negative
Consequence Type: Splice-affecting (SPLICE) 0.00 0.00 Non-significant