Top
CREBBP 16:3728115:T (P2311Q) × BRAIN ×
Driver potential information
Model BoostDM class BoostDM score
(BRAIN) CNS/Brain Driver 0.85
Feature importance

Place the mouse pointer over a mutational feature for additional information. See the FAQs for more details about the feature importance.

Feature Feature value SHAP value
Linear Clustering Score (LCS) 0.00 -0.10 Non-significant
3D Clustering in Cancer Type (3CT) 0.00 0.00 Non-significant
Recurrent in PFAM Domain (DOM) 0.00 -0.63 Medium negative
PhyloP 100-way Score (PHYLOP) 9.40 1.77 High positive
Stop Codon in Last Exon (NMD) 0.00 0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Methylation (METHYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Phosphorylation (PHOS) 0.00 0.00 Non-significant
Post-translational Modification Site: Regulatory site (REG) 0.00 0.00 Non-significant
Post-translational Modification Site: Ubiquitination (UB) 0.00 0.00 Non-significant
Consequence Type: Missense (MISSENSE) 1.00 -0.20 Medium negative
Consequence Type: Nonsense (NONSENSE) 0.00 -0.11 Medium negative
Consequence Type: Splice-affecting (SPLICE) 0.00 0.00 Non-significant