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CREBBP 16:3731800:T (Y1622*) × MBT ×
Driver potential information
Model BoostDM class BoostDM score
(MBT) Miscellaneous Brain Tumor Passenger 0.44
Feature importance

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Feature Feature value SHAP value
Linear Clustering Score (LCS) 0.00 -0.27 Medium negative
3D Clustering in Cancer Type (3CT) 0.00 0.00 Non-significant
Recurrent in PFAM Domain (DOM) 2.00 0.96 Medium positive
PhyloP 100-way Score (PHYLOP) -0.33 -1.26 High negative
Stop Codon in Last Exon (NMD) 0.00 0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Methylation (METHYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Phosphorylation (PHOS) 1.00 0.00 Non-significant
Post-translational Modification Site: Regulatory site (REG) 0.00 0.00 Non-significant
Post-translational Modification Site: Ubiquitination (UB) 0.00 0.00 Non-significant
Consequence Type: Missense (MISSENSE) 0.00 0.23 Medium positive
Consequence Type: Nonsense (NONSENSE) 1.00 0.21 Medium positive
Consequence Type: Splice-affecting (SPLICE) 0.00 0.00 Non-significant