Top
CREBBP 16:3757374:T (Y1204*) × MBN ×
Driver potential information
Model BoostDM class BoostDM score
(MBN) Mature B-Cell Neoplasms Driver 0.85
Feature importance

Place the mouse pointer over a mutational feature for additional information. See the FAQs for more details about the feature importance.

Feature Feature value SHAP value
Linear Clustering Score (LCS) 0.00 -0.05 Non-significant
3D Clustering in Cancer Type (3CT) 0.00 0.00 Non-significant
Recurrent in PFAM Domain (DOM) 1.00 0.27 Medium positive
PhyloP 100-way Score (PHYLOP) 1.71 -0.80 Medium negative
Stop Codon in Last Exon (NMD) 0.00 0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Methylation (METHYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Phosphorylation (PHOS) 0.00 0.00 Non-significant
Post-translational Modification Site: Regulatory site (REG) 0.00 0.00 Non-significant
Post-translational Modification Site: Ubiquitination (UB) 0.00 0.00 Non-significant
Consequence Type: Missense (MISSENSE) 0.00 0.30 Medium positive
Consequence Type: Nonsense (NONSENSE) 1.00 0.97 Medium positive
Consequence Type: Splice-affecting (SPLICE) 0.00 -0.02 Non-significant