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EGFR 7:55198818:A (Q935K) × GBM ×
Driver potential information
Model BoostDM class BoostDM score
(GBM) Glioblastoma Multiforme Passenger 0.02
Feature importance

Place the mouse pointer over a mutational feature for additional information. See the FAQs for more details about the feature importance.

Feature Feature value SHAP value
Linear Clustering Score (LCS) 0.00 -0.01 Non-significant
3D Clustering in Cancer Type (3CT) 0.00 -1.01 High negative
Recurrent in PFAM Domain (DOM) 1.00 -0.88 Medium negative
PhyloP 100-way Score (PHYLOP) 7.88 -0.07 Non-significant
Stop Codon in Last Exon (NMD) 0.00 0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Methylation (METHYLATION) 0.00 -0.02 Non-significant
Post-translational Modification Site: Phosphorylation (PHOS) 0.00 -0.04 Non-significant
Post-translational Modification Site: Regulatory site (REG) 0.00 0.00 Non-significant
Post-translational Modification Site: Ubiquitination (UB) 0.00 0.00 Non-significant
Consequence Type: Missense (MISSENSE) 1.00 0.19 Medium positive
Consequence Type: Nonsense (NONSENSE) 0.00 0.00 Non-significant
Consequence Type: Splice-affecting (SPLICE) 0.00 0.00 Non-significant