Top
FBXW7 4:152326168:A (L494F) × UCEC ×
Driver potential information
Model BoostDM class BoostDM score
(UCEC) Endometrial Carcinoma Passenger 0.01
Feature importance

Place the mouse pointer over a mutational feature for additional information. See the FAQs for more details about the feature importance.

Feature Feature value SHAP value
Linear Clustering Score (LCS) 0.00 -0.09 Non-significant
3D Clustering in Cancer Type (3CT) 0.00 -1.27 High negative
Recurrent in PFAM Domain (DOM) 2.00 0.34 Medium positive
PhyloP 100-way Score (PHYLOP) 1.76 -0.75 Medium negative
Stop Codon in Last Exon (NMD) 0.00 0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Methylation (METHYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Phosphorylation (PHOS) 0.00 0.00 Non-significant
Post-translational Modification Site: Regulatory site (REG) 0.00 0.00 Non-significant
Post-translational Modification Site: Ubiquitination (UB) 0.00 0.00 Non-significant
Consequence Type: Missense (MISSENSE) 1.00 0.04 Non-significant
Consequence Type: Nonsense (NONSENSE) 0.00 -0.24 Medium negative
Consequence Type: Splice-affecting (SPLICE) 0.00 0.00 Non-significant