BoostDM

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FLT3 13:28034391:C (I538M) × MNM ×

Driver potential information

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Model	BoostDM class	BoostDM score
(MNM) Myeloid Neoplasm	Passenger	0.46

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Feature importance

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Place the mouse pointer over a mutational feature for additional information. See the FAQs for more details about the feature importance.

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Feature	Feature value	SHAP value
PhyloP 100-way Score (PHYLOP)	1.71	0.73 Medium positive
Consequence Type: Missense (MISSENSE)	1.00	0.19 Medium positive
Consequence Type: Splice-affecting (SPLICE)	0.00	0.00 Non-significant
Consequence Type: Nonsense (NONSENSE)	0.00	0.00 Non-significant
Post-translational Modification Site: Ubiquitination (UB)	0.00	0.00 Non-significant
Post-translational Modification Site: Regulatory site (REG)	0.00	0.00 Non-significant
Post-translational Modification Site: Phosphorylation (PHOS)	0.00	0.00 Non-significant
Post-translational Modification Site: Methylation (METHYLATION)	0.00	0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION)	0.00	0.00 Non-significant
Stop Codon in Last Exon (NMD)	0.00	0.00 Non-significant

Showing 1 to 10 of 13 entries