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FOXA1 14:37591975:A (K270M) × PRAD ×
Driver potential information
Model BoostDM class BoostDM score
(PRAD) Prostate Adenocarcinoma Driver 0.92
Feature importance

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Feature Feature value SHAP value
Linear Clustering Score (LCS) 1.00 0.80 Medium positive
3D Clustering in Cancer Type (3CT) 0.00 -0.43 Medium negative
Recurrent in PFAM Domain (DOM) 0.00 -0.29 Medium negative
PhyloP 100-way Score (PHYLOP) 5.99 0.87 Medium positive
Stop Codon in Last Exon (NMD) 0.00 0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION) 1.00 0.00 Non-significant
Post-translational Modification Site: Methylation (METHYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Phosphorylation (PHOS) 0.00 0.00 Non-significant
Post-translational Modification Site: Regulatory site (REG) 0.00 0.00 Non-significant
Post-translational Modification Site: Ubiquitination (UB) 0.00 0.00 Non-significant
Consequence Type: Missense (MISSENSE) 1.00 0.12 Medium positive
Consequence Type: Nonsense (NONSENSE) 0.00 0.00 Non-significant
Consequence Type: Splice-affecting (SPLICE) 0.00 0.00 Non-significant