BoostDM

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KRAS 12:25225679:A (Q129*) × NSCLC ×

Driver potential information

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Model	BoostDM class	BoostDM score
(NSCLC) Non-Small Cell Lung Cancer	Passenger	0.01

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Feature importance

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Place the mouse pointer over a mutational feature for additional information. See the FAQs for more details about the feature importance.

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Feature	Feature value	SHAP value
Consequence Type: Nonsense (NONSENSE)	1.00	0.82 Medium positive
Consequence Type: Splice-affecting (SPLICE)	0.00	0.00 Non-significant
Post-translational Modification Site: Ubiquitination (UB)	0.00	0.00 Non-significant
Post-translational Modification Site: Regulatory site (REG)	0.00	0.00 Non-significant
Post-translational Modification Site: Phosphorylation (PHOS)	0.00	0.00 Non-significant
Post-translational Modification Site: Methylation (METHYLATION)	0.00	0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION)	0.00	0.00 Non-significant
Stop Codon in Last Exon (NMD)	0.00	0.00 Non-significant
3D Clustering in Cancer Type (3CT)	0.00	-2.31 High negative
PhyloP 100-way Score (PHYLOP)	8.12	-0.31 Medium negative

Showing 1 to 10 of 13 entries