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MAP3K1 5:56893565:A (S1475*) × SOLID ×
Driver potential information
Model BoostDM class BoostDM score
(SOLID) Solid cancer Driver 1.00
Feature importance

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Feature Feature value SHAP value
Linear Clustering Score (LCS) 0.00 0.00 Non-significant
3D Clustering in Cancer Type (3CT) 0.00 0.00 Non-significant
Recurrent in PFAM Domain (DOM) 2.00 -0.06 Non-significant
PhyloP 100-way Score (PHYLOP) 6.89 0.49 Medium positive
Stop Codon in Last Exon (NMD) 1.00 0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Methylation (METHYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Phosphorylation (PHOS) 0.00 0.00 Non-significant
Post-translational Modification Site: Regulatory site (REG) 0.00 0.00 Non-significant
Post-translational Modification Site: Ubiquitination (UB) 0.00 0.00 Non-significant
Consequence Type: Missense (MISSENSE) 0.00 0.23 Medium positive
Consequence Type: Nonsense (NONSENSE) 1.00 2.07 High positive
Consequence Type: Splice-affecting (SPLICE) 0.00 -0.08 Non-significant