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PIK3CA 3:179209695:T (K416*) × GBM ×
Driver potential information
Model BoostDM class BoostDM score
(GBM) Glioblastoma Multiforme Driver 0.72
Feature importance

Place the mouse pointer over a mutational feature for additional information. See the FAQs for more details about the feature importance.

Feature Feature value SHAP value
Linear Clustering Score (LCS) 0.00 -0.04 Non-significant
3D Clustering in Cancer Type (3CT) 0.00 -0.75 Medium negative
Recurrent in PFAM Domain (DOM) 1.00 -0.08 Non-significant
PhyloP 100-way Score (PHYLOP) 8.89 1.20 High positive
Stop Codon in Last Exon (NMD) 0.00 0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Methylation (METHYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Phosphorylation (PHOS) 0.00 0.00 Non-significant
Post-translational Modification Site: Regulatory site (REG) 0.00 0.00 Non-significant
Post-translational Modification Site: Ubiquitination (UB) 0.00 0.00 Non-significant
Consequence Type: Missense (MISSENSE) 0.00 0.02 Non-significant
Consequence Type: Nonsense (NONSENSE) 1.00 0.08 Non-significant
Consequence Type: Splice-affecting (SPLICE) 0.00 0.00 Non-significant