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RB1 13:48345189:T (K164*) × GB ×
Driver potential information
Model BoostDM class BoostDM score
(GB) Glioblastoma Driver 0.99
Feature importance

Place the mouse pointer over a mutational feature for additional information. See the FAQs for more details about the feature importance.

Feature Feature value SHAP value
Linear Clustering Score (LCS) 0.00 0.00 Non-significant
3D Clustering in Cancer Type (3CT) 0.00 0.00 Non-significant
Recurrent in PFAM Domain (DOM) 1.00 0.00 Non-significant
PhyloP 100-way Score (PHYLOP) 5.86 0.19 Medium positive
Stop Codon in Last Exon (NMD) 0.00 0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Methylation (METHYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Phosphorylation (PHOS) 0.00 0.00 Non-significant
Post-translational Modification Site: Regulatory site (REG) 0.00 0.00 Non-significant
Post-translational Modification Site: Ubiquitination (UB) 0.00 0.00 Non-significant
Consequence Type: Missense (MISSENSE) 0.00 0.90 Medium positive
Consequence Type: Nonsense (NONSENSE) 1.00 1.10 High positive
Consequence Type: Splice-affecting (SPLICE) 0.00 -0.11 Medium negative