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TP53 17:7669616:C (S392*) × STAD ×
Driver potential information
Model BoostDM class BoostDM score
(STAD) Stomach Adenocarcinoma Driver 0.58
Feature importance

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Feature Feature value SHAP value
Linear Clustering Score (LCS) 0.00 -0.05 Non-significant
3D Clustering in Cancer Type (3CT) 0.00 -0.53 Medium negative
Recurrent in PFAM Domain (DOM) 0.00 -0.70 Medium negative
PhyloP 100-way Score (PHYLOP) 4.29 -0.38 Medium negative
Stop Codon in Last Exon (NMD) 1.00 0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Methylation (METHYLATION) 0.00 -0.01 Non-significant
Post-translational Modification Site: Phosphorylation (PHOS) 1.00 -0.03 Non-significant
Post-translational Modification Site: Regulatory site (REG) 1.00 -0.16 Medium negative
Post-translational Modification Site: Ubiquitination (UB) 0.00 0.00 Non-significant
Consequence Type: Missense (MISSENSE) 0.00 0.38 Medium positive
Consequence Type: Nonsense (NONSENSE) 1.00 1.66 High positive
Consequence Type: Splice-affecting (SPLICE) 0.00 -0.09 Non-significant