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TP53 17:7669617:G (S392P) × LIVER ×
Driver potential information
Model BoostDM class BoostDM score
(LIVER) Liver Passenger 0.00
Feature importance

Place the mouse pointer over a mutational feature for additional information. See the FAQs for more details about the feature importance.

Feature Feature value SHAP value
Linear Clustering Score (LCS) 0.00 -0.03 Non-significant
3D Clustering in Cancer Type (3CT) 0.00 -1.63 High negative
Recurrent in PFAM Domain (DOM) 0.00 -0.62 Medium negative
PhyloP 100-way Score (PHYLOP) 4.01 -0.64 Medium negative
Stop Codon in Last Exon (NMD) 0.00 0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Methylation (METHYLATION) 0.00 -0.01 Non-significant
Post-translational Modification Site: Phosphorylation (PHOS) 1.00 0.18 Medium positive
Post-translational Modification Site: Regulatory site (REG) 1.00 0.10 Non-significant
Post-translational Modification Site: Ubiquitination (UB) 0.00 0.00 Non-significant
Consequence Type: Missense (MISSENSE) 1.00 -0.30 Medium negative
Consequence Type: Nonsense (NONSENSE) 0.00 -0.17 Medium negative
Consequence Type: Splice-affecting (SPLICE) 0.00 -0.31 Medium negative