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TP53 17:7669631:A (T387I) × ESCA ×
Driver potential information
Model BoostDM class BoostDM score
(ESCA) Esophageal Adenocarcinoma Passenger 0.00
Feature importance

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Feature Feature value SHAP value
Linear Clustering Score (LCS) 0.00 -0.11 Medium negative
3D Clustering in Cancer Type (3CT) 0.00 -1.82 High negative
Recurrent in PFAM Domain (DOM) 0.00 -0.88 Medium negative
PhyloP 100-way Score (PHYLOP) -0.21 -0.78 Medium negative
Stop Codon in Last Exon (NMD) 0.00 0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Methylation (METHYLATION) 0.00 -0.05 Non-significant
Post-translational Modification Site: Phosphorylation (PHOS) 1.00 0.27 Medium positive
Post-translational Modification Site: Regulatory site (REG) 1.00 0.07 Non-significant
Post-translational Modification Site: Ubiquitination (UB) 0.00 0.00 Non-significant
Consequence Type: Missense (MISSENSE) 1.00 -0.21 Medium negative
Consequence Type: Nonsense (NONSENSE) 0.00 -0.63 Medium negative
Consequence Type: Splice-affecting (SPLICE) 0.00 -0.31 Medium negative