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TP53 17:7669635:A (K386*) × ENCG ×
Driver potential information
Model BoostDM class BoostDM score
(ENCG) Encapsulated Glioma Passenger 0.21
Feature importance

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Feature Feature value SHAP value
Linear Clustering Score (LCS) 0.00 -0.05 Non-significant
3D Clustering in Cancer Type (3CT) 0.00 -1.40 High negative
Recurrent in PFAM Domain (DOM) 0.00 -0.55 Medium negative
PhyloP 100-way Score (PHYLOP) 3.43 -0.35 Medium negative
Stop Codon in Last Exon (NMD) 1.00 0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION) 1.00 0.00 Non-significant
Post-translational Modification Site: Methylation (METHYLATION) 1.00 0.01 Non-significant
Post-translational Modification Site: Phosphorylation (PHOS) 0.00 0.00 Non-significant
Post-translational Modification Site: Regulatory site (REG) 1.00 -0.03 Non-significant
Post-translational Modification Site: Ubiquitination (UB) 1.00 -0.01 Non-significant
Consequence Type: Missense (MISSENSE) 0.00 0.28 Medium positive
Consequence Type: Nonsense (NONSENSE) 1.00 1.56 High positive
Consequence Type: Splice-affecting (SPLICE) 0.00 -0.04 Non-significant