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TP53 17:7669676:C (K372R) × LUSC ×
Driver potential information
Model BoostDM class BoostDM score
(LUSC) Lung Squamous Cell Carcinoma Passenger 0.00
Feature importance

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Feature Feature value SHAP value
Linear Clustering Score (LCS) 0.00 -0.06 Non-significant
3D Clustering in Cancer Type (3CT) 0.00 -1.22 High negative
Recurrent in PFAM Domain (DOM) 0.00 -1.13 High negative
PhyloP 100-way Score (PHYLOP) 3.43 0.10 Non-significant
Stop Codon in Last Exon (NMD) 0.00 0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION) 1.00 0.24 Medium positive
Post-translational Modification Site: Methylation (METHYLATION) 1.00 0.18 Medium positive
Post-translational Modification Site: Phosphorylation (PHOS) 0.00 0.00 Non-significant
Post-translational Modification Site: Regulatory site (REG) 1.00 0.02 Non-significant
Post-translational Modification Site: Ubiquitination (UB) 1.00 0.27 Medium positive
Consequence Type: Missense (MISSENSE) 1.00 -0.14 Medium negative
Consequence Type: Nonsense (NONSENSE) 0.00 -0.44 Medium negative
Consequence Type: Splice-affecting (SPLICE) 0.00 -0.45 Medium negative