Top
TP53 17:7669682:A (K370M) × NSCLC ×
Driver potential information
Model BoostDM class BoostDM score
(NSCLC) Non-Small Cell Lung Cancer Passenger 0.00
Feature importance

Place the mouse pointer over a mutational feature for additional information. See the FAQs for more details about the feature importance.

Feature Feature value SHAP value
Linear Clustering Score (LCS) 0.00 -0.03 Non-significant
3D Clustering in Cancer Type (3CT) 0.00 -1.24 High negative
Recurrent in PFAM Domain (DOM) 0.00 -1.34 High negative
PhyloP 100-way Score (PHYLOP) 3.43 -0.39 Medium negative
Stop Codon in Last Exon (NMD) 0.00 0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION) 1.00 0.24 Medium positive
Post-translational Modification Site: Methylation (METHYLATION) 1.00 0.28 Medium positive
Post-translational Modification Site: Phosphorylation (PHOS) 0.00 0.00 Non-significant
Post-translational Modification Site: Regulatory site (REG) 1.00 -0.15 Medium negative
Post-translational Modification Site: Ubiquitination (UB) 1.00 0.23 Medium positive
Consequence Type: Missense (MISSENSE) 1.00 -0.23 Medium negative
Consequence Type: Nonsense (NONSENSE) 0.00 -0.32 Medium negative
Consequence Type: Splice-affecting (SPLICE) 0.00 -0.24 Medium negative