Top
TP53 17:7675064:T (S183*) × LGGNOS ×
Driver potential information
Model BoostDM class BoostDM score
(LGGNOS) Low-Grade Glioma Driver 0.78
Feature importance

Place the mouse pointer over a mutational feature for additional information. See the FAQs for more details about the feature importance.

Feature Feature value SHAP value
Linear Clustering Score (LCS) 1.00 -0.15 Medium negative
3D Clustering in Cancer Type (3CT) 0.00 -1.66 High negative
Recurrent in PFAM Domain (DOM) 2.00 0.09 Non-significant
PhyloP 100-way Score (PHYLOP) 1.11 0.35 Medium positive
Stop Codon in Last Exon (NMD) 0.00 0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Methylation (METHYLATION) 0.00 -0.03 Non-significant
Post-translational Modification Site: Phosphorylation (PHOS) 1.00 0.10 Non-significant
Post-translational Modification Site: Regulatory site (REG) 1.00 -0.03 Non-significant
Post-translational Modification Site: Ubiquitination (UB) 0.00 0.00 Non-significant
Consequence Type: Missense (MISSENSE) 0.00 0.20 Medium positive
Consequence Type: Nonsense (NONSENSE) 1.00 1.72 High positive
Consequence Type: Splice-affecting (SPLICE) 0.00 -0.05 Non-significant