Top
TP53 17:7676037:G (L111P) × CSCC ×
Driver potential information
Model BoostDM class BoostDM score
(CSCC) Cutaneous Squamous Cell Carcinoma Driver 0.74
Feature importance

Place the mouse pointer over a mutational feature for additional information. See the FAQs for more details about the feature importance.

Feature Feature value SHAP value
Linear Clustering Score (LCS) 0.00 -0.51 Medium negative
3D Clustering in Cancer Type (3CT) 1.00 0.35 Medium positive
Recurrent in PFAM Domain (DOM) 2.00 0.05 Non-significant
PhyloP 100-way Score (PHYLOP) 7.47 0.84 Medium positive
Stop Codon in Last Exon (NMD) 0.00 0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Methylation (METHYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Phosphorylation (PHOS) 0.00 0.00 Non-significant
Post-translational Modification Site: Regulatory site (REG) 0.00 0.00 Non-significant
Post-translational Modification Site: Ubiquitination (UB) 0.00 0.00 Non-significant
Consequence Type: Missense (MISSENSE) 1.00 -0.11 Medium negative
Consequence Type: Nonsense (NONSENSE) 0.00 -0.09 Non-significant
Consequence Type: Splice-affecting (SPLICE) 0.00 -0.07 Non-significant