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USP6 17:5132922:T (E70*) × SOLID ×
Driver potential information
Model BoostDM class BoostDM score
(SOLID) Solid cancer Driver 0.99
Feature importance

Place the mouse pointer over a mutational feature for additional information. See the FAQs for more details about the feature importance.

Feature Feature value SHAP value
Linear Clustering Score (LCS) 2.00 1.83 High positive
3D Clustering in Cancer Type (3CT) 0.00 -0.11 Medium negative
Recurrent in PFAM Domain (DOM) 0.00 0.01 Non-significant
PhyloP 100-way Score (PHYLOP) 2.04 0.19 Medium positive
Stop Codon in Last Exon (NMD) 0.00 0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Methylation (METHYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Phosphorylation (PHOS) 0.00 0.00 Non-significant
Post-translational Modification Site: Regulatory site (REG) 0.00 0.00 Non-significant
Post-translational Modification Site: Ubiquitination (UB) 0.00 0.00 Non-significant
Consequence Type: Missense (MISSENSE) 0.00 -0.16 Medium negative
Consequence Type: Nonsense (NONSENSE) 1.00 0.04 Non-significant
Consequence Type: Splice-affecting (SPLICE) 0.00 0.00 Non-significant