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VHL 3:10142148:G (L101V) × RCC ×
Driver potential information
Model BoostDM class BoostDM score
(RCC) Renal Cell Carcinoma Passenger 0.01
Feature importance

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Feature Feature value SHAP value
Linear Clustering Score (LCS) 2.00 -0.07 Non-significant
3D Clustering in Cancer Type (3CT) 0.00 0.00 Non-significant
Recurrent in PFAM Domain (DOM) 2.00 0.71 Medium positive
PhyloP 100-way Score (PHYLOP) 1.27 -2.11 High negative
Stop Codon in Last Exon (NMD) 0.00 0.00 Non-significant
Post-translational Modification Site: Acetylation (ACETYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Methylation (METHYLATION) 0.00 0.00 Non-significant
Post-translational Modification Site: Phosphorylation (PHOS) 0.00 -0.02 Non-significant
Post-translational Modification Site: Regulatory site (REG) 0.00 -0.02 Non-significant
Post-translational Modification Site: Ubiquitination (UB) 0.00 0.00 Non-significant
Consequence Type: Missense (MISSENSE) 1.00 -0.15 Medium negative
Consequence Type: Nonsense (NONSENSE) 0.00 -0.46 Medium negative
Consequence Type: Splice-affecting (SPLICE) 0.00 0.00 Non-significant